Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5853541 | Food and Chemical Toxicology | 2012 | 7 Pages |
Abstract
⺠NiO NP applications are accompanied by limited safety regulations & toxicity data. ⺠NiO NP-induced cytotoxicity and oxidative stress in HEp-2 and MCF-7 cells. ⺠NiO NP-induced caspapse-3 activation and DNA fragmentation in both types of cells. ⺠Curcumin attenuated NiO NP-induced cytotoxicity in both types of cells. ⺠Curcumin also ameliorated NiO NP-induced ROS & LPO generation and GSH depletion.
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Authors
Maqsood A. Siddiqui, Maqusood Ahamed, Javed Ahmad, M.A. Majeed Khan, Javed Musarrat, Abdulaziz A. Al-Khedhairy, Salman A. Alrokayan,