Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5853547 | Food and Chemical Toxicology | 2012 | 4 Pages |
Abstract
⺠Furan reduced the %DNA in comet tails of turkey egg hepatocytes at 24 h. ⺠Finding of reduced comet tails indicates DNA-protein crosslinks. ⺠Proteinase digestion increased comet tails, showing DNA strand breaks. ⺠1,3-Propanediol (PD) was not toxic and induced DNA-protein crosslinks. ⺠Furan and PD produced DNA damage in turkey egg hepatocytes.
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Authors
Alan M. Jeffrey, Klaus D. Brunnemann, Jian-Dong Duan, Josef Schlatter, Gary M. Williams,