| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5853577 | Food and Chemical Toxicology | 2012 | 6 Pages |
Abstract
⺠Coleus forskohlii root extract (CFE) induced activities of hepatic drug metabolizing enzymes (CYPs and GST) in mice. ⺠CFE increased mRNA expression of CYPs and GST with dose related responses. ⺠Intake of two different sources of CFE showed similar response toward inductions of CYPs. ⺠Induction of CYPs by CFE was detected at 1 week of feeding and rapidly recovered after discontinuation. ⺠Forskolin was not involved in the marked induction of CYPs by CFE.
Related Topics
Life Sciences
Agricultural and Biological Sciences
Food Science
Authors
Nantiga Virgona, Kaori Yokotani, Yuko Yamazaki, Fumio Shimura, Tsuyoshi Chiba, Yuko Taki, Shizuo Yamada, Kazumasa Shinozuka, Masatsune Murata, Keizo Umegaki,