Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5853598 | Food and Chemical Toxicology | 2012 | 11 Pages |
Abstract
⺠LJ provided protection of SH-SY5Y cells from the cytotoxicity induced by 6-OHDA. ⺠LJ inhibited 6-OHDA-induced mitochondria membrane dysfunction in SH-SY5Y cells. ⺠LJ protected 6-OHDA-induced the activation of MAPKs, PI3K/Akt, and NF-κB. ⺠LJ is a possible candidate that can target oxidative stress associated with PD.
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Authors
Seung-Hwan Kwon, Sa-Ik Hong, Yang-Hee Jung, Min-Jung Kim, Sun-Yeou Kim, Hyoung-Chun Kim, Seok-Yong Lee, Choon-Gon Jang,