| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5853612 | Food and Chemical Toxicology | 2012 | 7 Pages |
Abstract
⺠Consumers worldwide could benefit from expanded use of gum ghatti in food products. ⺠Gum ghatti was tested in a full battery of GLP compliant genotoxicity assays. ⺠Tests included Ames, chromosome aberration, and in vivo micronucleus/Comet assays. ⺠No evidence of genotoxicity was observed up to concentrations exceeding the maximum levels recommended by OECD guidelines. ⺠Gum ghatti is safe for human consumption at higher than currently accepted limits.
Keywords
JECFAGLPMN-RETLMWJaCVAMOECDFDAGumChromosome damageDNA damageUS Food and Drug Administrationstandard deviationChoChinese Hamster OvaryGood Laboratory PracticeMutagenicityRETstandard error of the meanmicronucleated reticulocytesOrganization for Economic Cooperation and DevelopmentJoint FAO/WHO Expert Committee on Food AdditivesSEMICHFood additivemicronucleus or micronucleilow molecular weightInternational Conference on Harmonization
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Authors
Cheryl A. Hobbs, Carol Swartz, Robert Maronpot, Jeffrey Davis, Leslie Recio, Shim-mo Hayashi,