Lantana macrophylla Schauer (Verbenaceae) ethanolic extract induces activation of ERK1/2 and p38 MAPKs pathway and Ca2+ imbalance in human trophoblasts derived cell lines

Article ID	Journal	Published Year	Pages	File Type
5853657	Food and Chemical Toxicology	2012	12 Pages	PDF

Abstract

âº Lantana macrophylla affects placental calcium transport. âº Placental cell turnover can be affected by Lantana species. âº Trophoblast MAPK pathway are regulated by L. macrophylla.

Keywords

Verbenaceae TBST HBSS SFK NCX HRP HPL TRPV GAPDH EGTA PMCA ECL TCTP RIPA FCS PBS p38 nuclear magnetic resonance 1,25-(OH)2D3 BeWo BSA cAMP DMSO ERK1/2 JEG-3 MAPK Na+/Ca2+ exchanger [Ca2+]i Cyclic adenosine monophosphate Radio immunoprecipitation assay bovine serum albumin ethylene glycol tetraacetic acid Ultraviolet HCG enhanced chemiluminescence Tris-buffered saline Tween-20 NMR Ca2+ uptake Dimethyl sulfoxide fetal calf serum plasma membrane calcium ATPase intracellular Ca2+ concentration phosphate buffer saline Human placental lactogen LAn MEM Hank’s balanced salt solution HCG, Human chorionic gonadotropin Vitamin D3 transient receptor potential vanilloid Horseradish peroxidase Translationally controlled tumor protein mitogen-activated protein kinase glyceraldehyde-3-phosphate dehydrogenase

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Lantana macrophylla Schauer (Verbenaceae) ethanolic extract induces activation of ERK1/2 and p38 MAPKs pathway and Ca2+ imbalance in human trophoblasts derived cell lines

Authors

Aline O. da ConceiçÃ£o, Fernando F. de Oliveira, Rosilene A. de Oliveira, Ademir Junior, Larissa Takser, Carlos Reyes-Moreno, Julie Lafond,