Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5853731 | Food and Chemical Toxicology | 2011 | 10 Pages |
Abstract
⺠Rats and mice were administered Kava Kava by gavage for two weeks, thirteen weeks or two years. ⺠Prechronic studies revealed dose-related increases in liver weights and hepatocellular hypertrophy. ⺠Dose-related increases in non-neoplastic lesions seen in rats and mice in chronic studies. ⺠Additionally, hepatocarcinogenecity seen in male and female mice with chronic exposure.
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Authors
Mamta Behl, Abraham Nyska, Rajendra S. Chhabra, Gregory S. Travlos, Laurene M. Fomby, Barney R. Sparrow, Milton R. Hejtmancik, Po C. Chan,