| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5854107 | Food and Chemical Toxicology | 2011 | 8 Pages |
Abstract
⺠We use rat during developmental d-galactose exposure to induce hearing loss. ⺠We examine effect of β-carotene on hearing loss in newborn rats. ⺠d-Galactose induces hair cell apoptosis mediated by activation of caspase-3. ⺠β-Carotene prevents hearing loss and exhibits anti-apoptoic property.
Keywords
MDAPNDGSHDPOAEGSH-Pxβ-carotenedistortion product otoacoustic emissionterminal deoxynucleotidyl transferase-mediated dUTP nick end-labelingTUNELApoptosisgestational daypostnatal daySODOtotoxicitySuper Oxide DismutasemalondialdehydeNewbornCaspase-3high performance liquid chromatographyHPLCGlutathioneglutathione peroxidase
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Authors
Fei Yu, Shuai Hao, Yue Zhao, Hui Yang, Xiao-lan Fan, Jun Yang,