Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5854108 | Food and Chemical Toxicology | 2011 | 6 Pages |
Abstract
⺠The protective effects of rhein on Acetaminophen (APAP)-induced hepatotoxicity and nephrotoxicity in rats were investigated in this study. ⺠The histopathological damage of liver and kidney could be significantly ameliorated by rhein treatment. ⺠The protective effects of rhein against liver and kidney injuries might result from the amelioration of APAP-induced oxidative stress.
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Authors
Yan-Ling Zhao, Guang-De Zhou, Hong-Bo Yang, Jia-Bo Wang, Li-Mei Shan, Rui-sheng Li, Xiao-He Xiao,