| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5854119 | Food and Chemical Toxicology | 2011 | 6 Pages |
Abstract
⺠Hyperhomocysteinemia leads to a decrease of hepatic Nqo1 activity. ⺠Hyperhomocysteinemia leads to an increase of hepatic total Nat activity. ⺠Red wine polyphenol extract could counteract these variations of activity. ⺠Total hepatic Nat activity correlates with nitrotyrosine-modified protein levels.
Keywords
ERKNQO1SMZCBSp-aminosalicylic acidPON1NATXMEAHR2-AF2-aminofluoreneEpRENAD(P)H:quinone oxidoreductaseROStHcySulfamethazinecystathionine beta synthaseelectrophile response elementMicePAStotal plasma homocysteinehomocysteineParaoxonase-1PolyphenolsLiverextracellular signal-regulated kinaseReactive oxygen speciesarylhydrocarbon receptor
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Authors
Christophe Noll, Julien Dairou, Clémentine Ripoll, Jean-Louis Paul, Jean-Marie Dupret, Jean-Maurice Delabar, Fernando Rodrigues-Lima, Nathalie Janel,