| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5854285 | Food and Chemical Toxicology | 2010 | 4 Pages |
Abstract
Lead is a persistent and common environmental contaminant, which chiefly plays a significant role in modern industry. Coenzyme Q acts as electron and proton carrier in mitochondria and functions as an antioxidant in its reduced form (ubiquinol). To investigate the hazardous effects of lead on the coenzyme Q level, rats were injected i.p. with lead acetate (5Â mg/kg b.wt. daily for 6Â weeks). Our results showed that the levels of both oxidized (ubiquinone) and reduced (ubiquinol) forms of coenzyme Q9 and Q10 in serum, brain, liver and kidney of lead-treated rats are quite different depending on the organ tissue type.
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Authors
Gamil M. Abdallah, El-Sayed M. El-Sayed, Osama M. Abo-Salem,