| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6398384 | Food Research International | 2013 | 9 Pages |
The interaction of the antioxidant Quercetin with the hydroxyl radical (generated by Fenton's reaction) in presence of cationic (DDEAB, DTPB), nonionic (Brij30), anionic (SDBS, SDS) and their mixed binary and ternary surfactant systems (DDEAB-Brij30, DTPB-Brij30, SDBS-Brij30, SDS-Brij30, DDEAB-DTPB-Brij30, SDBS-SDS-Brij30) was followed by spectrophotometric and tensiometric methods to evaluate oxidation kinetics and hydroxyl radical scavenging activity (RSA) of Quercetin. The analysis of the data was done using the first order kinetic model. Coefficient of Determination (R2) was used as a statistical measure for comparison of the experimental values with the model simulated values. The rate of oxidation of Quercetin was found to depend on nature and concentration of the surfactant used. The rate constant of oxidation reaction (k) observed in different micellar systems with varying surfactant concentration exhibits the same trend as that of the RSA. Both k and RSA values of Quercetin were higher within ionic micelles than in nonionic micelles. In mixed binary micelles the values were intermediate between those for single surfactant systems except in DTPB-Brij30 where the values were higher. However, these values exhibited enhancement in mixed ternary cationic-cationic-nonionic surfactant systems when compared with anionic-anionic-nonionic mixed systems. The results are explained on the basis of compartmentalization and orientation of Quercetin in micellar nanostructures.
⺠Radical scavenging activity of Quercetin was studied in various mixed surfactants. ⺠Degradation rate was higher in cationic than in nonionic and anionic surfactants. ⺠RSA in the binary surfactant mixtures was intermediate than in single surfactants. ⺠In nonionic-cationic-cationic ternary systems the degradation rates were higher.
