Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7305348 | Appetite | 2018 | 8 Pages |
Abstract
There is evidence that oat β-glucan lowers appetite and ad libitum eating; however, not all studies are consistent, and the underpinning mechanisms are not entirely understood. We investigated the effects of 4â¯g high molecular weight (MW) oat β-glucan on ad libitum eating, subjective appetite, glycemia, insulinemia and plasma GLP-1 responses in 33 normal-weight subjects (22 female/11 male, mean age (y): 26.9â¯Â±â¯1.0, BMI (kg/m2): 23.5â¯Â±â¯0.4). The study followed a randomised double-blind, cross-over design with subjects fed two test breakfasts with and without oat β-glucan followed by an ad libitum test meal on two different days. Blood samples and ratings for subjective appetite were collected postprandially at regular time intervals. Oat β-glucan increased feelings of fullness (pâ¯=â¯0.048) and satiety (pâ¯=â¯0.034), but did not affect energy and amount eaten at the ad libitum test meal. There was a treatment by time interaction for plasma GLP-1, plasma insulin and blood glucose. GLP-1 was significantly reduced at 90â¯min (pâ¯=â¯0.021), blood glucose at 30â¯min (pâ¯=â¯0.008) and plasma insulin at 30 and 60â¯min (pâ¯=â¯0.002 and 0.017, respectively) following the oat β-glucan breakfast when compared with the control breakfast. Four grams of high MW oat β-glucan lowers appetite but not ad libitum eating and beneficially modulates postprandial glycaemia, it does however, not increase plasma GLP-1 secretion.
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Authors
Suzanne M.M. Zaremba, Iain F. Gow, Sandra Drummond, Jane T. McCluskey, Robert E. Steinert,