Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8409092 | Current Opinion in Food Science | 2018 | 16 Pages |
Abstract
Many functional foods have been developed which propose to lower circulating cholesterol concentrations, such as plant sterols or β-glucan. However, response to these foods is often highly variable between individuals, with some benefiting from cholesterol lowering and while others do not. One of the potential causes of this inter-individual variability in response could be genetics. This review looks at the associations between the single nucleotide polymorphism rs3808607 in the Cytochrome P450 Family 7 Subfamily A Member 1 (CYP7A1) gene, and variability in the response of circulation cholesterol concentrations following the consumption of various functional foods.
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Authors
Yongbo She, Dylan S MacKay, James D House, Peter JH Jones,