Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8428727 | Trends in Food Science & Technology | 2018 | 25 Pages |
Abstract
Bacterial cellulose shows good biocompatibility and hemocompatibility. CNC oxidation provides biologically beneficial impacts; for instance, the TEMPO- and periodate-oxidized CNCs have been shown to regulate some blood metabolic variables and improve the degradability in simulated human blood plasma, respectively. Spherical and carboxyl-bearing cellulose nanoparticles can be isolated through ammonium persulfate digestion. The sphericity of particles results in faster cellular uptake. Negatively-charged CNCs are non-mucoadhesive and thus upon ingestion can penetrate into the buccal and intestinal mucosa. One may augment the absorption of CNCs by targeted receptor-mediated endocytosis. It was postulated that sodium bicarbonate secretion into the duodenum can alter CNCs surface chemistry and influence CNC interaction with gut microbiota.
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Authors
Roya Koshani, Ashkan Madadlou,