Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8428847 | Trends in Food Science & Technology | 2016 | 33 Pages |
Abstract
During the past two decades, much attention has been focused on the antibacterial and antifungal potential of allicin against multi-drug resistant microorganisms. Despite promising in vitro results, the in vivo activity of allicin has not yet been well documented in preclinical and clinical efficacy trials. Due to some adverse effects, further studies are required to confirm the potential therapeutic use of allicin as an antimicrobial agent. Pharmacokinetic studies should be performed in order to improve the bioavailability of allicin by employing different delivery systems.
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Authors
Anna Marchese, Ramona Barbieri, Ana Sanches-Silva, Maria Daglia, Seyed Fazel Nabavi, Nematollah Jonaidi Jafari, Morteza Izadi, Marjan Ajami, Seyed Mohammad Nabavi,