Engineered emulsions for obesity treatment

Pectin and alginate-enriched milk protein-stabilized emulsions may form emulgel lumps in the stomach; however, more efficient tactics are required to guaranty the intragastric gelation and pass of emulsions as stable through the upper small intestine. Cellulose nanocrystals (CNCs) are highly acid and digestion-resistant particles with documented ability to form Pickering emulsions. Surface carboxylation of CNCs by food-grade methods and fabrication of carboxylated CNC-stabilized emulsions would yield intragastrically gel-able and intestinally non-digestible foodstuffs for obesity treatment. A wisely designed emulsion can release enveloped pre-hydrolyzed oil cargo into the ileum for the lymphatic absorption.