Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8502455 | Meat Science | 2018 | 27 Pages |
Abstract
Fatty acid-binding protein 4 (FABP4) participates in fatty-acid transportation and variation in the gene has been reported to affect fat deposition in mammals. To assess the effects of variation in FABP4 on carcass and growth traits in sheep, two regions of the gene were investigated in 749 New Zealand Romney lambs. Five variants (A1â¯ââ¯E1) were found in region-1 (exon 2â¯ââ¯intron 2) and three variants (A2â¯ââ¯C2) were found in region-2 (exon 3â¯ââ¯intron 3). A1 was associated with a decrease in leg meat yield, loin meat yield and total meat yield, whereas A2 was associated with a decrease in weaning-weight and pre-weaning growth-rate. Haplotype A1-A2 was found to be associated with a decrease in birth-weight, pre-weaning growth-rate, hot carcass weight, loin meat yield, shoulder meat yield and total meat yield, while haplotype A1-B2 was associated with increased fat depth at the 12th rib (V-GR). Taken together, this supports the contention that variation in FABP4 affects growth and meat production in sheep.
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Authors
Wei Yan, Huitong Zhou, Jiang Hu, Yuzhu Luo, Jon G.H. Hickford,