Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8521029 | Journal of Food and Drug Analysis | 2018 | 8 Pages |
Abstract
81NC-8, an isosteviol derivative, exhibited inhibitory activity against the secretion of HBsAg and HBeAg. The action mechanism of NC-8 was distinct from those of typical HBV inhibitors. For further drug development, a bioanalytical method development, validation, and application to pharmacokinetic investigations of NC-8 were carried out.
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Authors
Baxter Hepburn Kachingwe, Yow-Shieng Uang, Tsurng-Juhn Huang, Li-Hsuan Wang, Shwu-Jiuan Lin,