Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8547293 | Food and Chemical Toxicology | 2018 | 8 Pages |
Abstract
Differences in toothpaste consumption depending on gender and on age were highlighted. As an example, frequency data were higher in adult women (2.0 dayâ1 on average) than in adult men (1.8 dayâ1 on average); amount per use data were higher in adult men (1.2â¯g on average) than in adult women (0.9â¯g on average). The frequency of use and the amount of toothpaste used per application increased with age. The exposure to toothpaste decreased with age. Children aged 2-6 were the most exposed to toothpaste with a P95 value equal to 8.2â¯mg/kgâ¯bw/day. Adult's P95 exposure value was equal to 2.8â¯mg/kgâ¯bw/day. Exposure values were in the same order of magnitude for both genders in children and in adults. These new data will be useful for safety assessors, especially children data which remain scarce.
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Authors
Marie-Pierre Gomez-Berrada, Anne-Sophie Ficheux, Inès Boudières, Myriam Chiter, Aurélie Rielland, Dominique De Javel, Alain-Claude Roudot, Pierre-Jacques Ferret,