Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8547923 | Food and Chemical Toxicology | 2018 | 9 Pages |
Abstract
- Furocoumarins are photoactive compounds occurring naturally in numerous plant species.
- Furocoumarins can form DNA crosslinks when photoactivated, thereby disrupting DNA replication.
- Phototherapy using furocoumarins with UVA have been associated with increased skin cancer risk.
- Estimates of the level of exposure to dietary furocoumarins are highly variable.
- Potential risks associated with dietary furocoumarin exposure have not been fully clarified.
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Authors
Melissa M. Melough, Eunyoung Cho, Ock K. Chun,