4-Methylthio-3-butenyl isothiocyanate mediates nuclear factor (erythroid-derived 2)-like 2 activation by regulating reactive oxygen species production in human esophageal epithelial cells

Article ID	Journal	Published Year	Pages	File Type
8548528	Food and Chemical Toxicology	2018	7 Pages	PDF

Keywords

Kelch like ECH associated protein 1 GCLC NQO1 HMOX1 SAPK AITC BITC AP-1 ITCs PEITC 4-Methylthio-3-butenyl isothiocyanate ERK NAC GSH mitogen-activated protein kinase-activated protein kinase Nrf2 Jnk MAPKAPK keap1 c-Jun N-terminal kinase MAPK NAD(P)H quinone dehydrogenase 1 ROS Isothiocyanates Isothiocyanate nuclear factor (erythroid-derived 2)-like 2 heme oxygenase 1 activator protein-1 mitogen-activated protein kinase Stress-activated protein kinase Phenethyl isothiocyanate Chemoprevention glutamate-cysteine ligase catalytic subunit extracellular signal-regulated kinase Glutathione Reactive oxygen species

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4-Methylthio-3-butenyl isothiocyanate mediates nuclear factor (erythroid-derived 2)-like 2 activation by regulating reactive oxygen species production in human esophageal epithelial cells

Authors

Tadashi Hirata, Young-Man Cho, Isamu Suzuki, Takeshi Toyoda, Jun-ichi Akagi, Yasushi Nakamura, Satoshi Numazawa, Kumiko Ogawa,