Causes and solutions to “globesity”: The new fa(s)t alarming global epidemic

Article ID	Journal	Published Year	Pages	File Type
9955032	Food and Chemical Toxicology	2018	84 Pages	PDF

Keywords

AMPK STAT3 LKB1 NF-κB ACC MCR CAT EMA Nrf2 FAS GAPDH ALT FFM HFD NPY AgRP POMC BAT LDL-C IGF-I SIRT sirtuin CCK HDL-C SDC1 NTS eCB GLP-1 PKC CART AP2 DIO pro-opiomelanocortin GIP MCP1 GLUT4 Neuromedin U PYY SOCS WHtR RBP4 IFNγ LPL WHR SREBPs HSL FGF-21 SPARC MSH PLIN1 PTP1B NMU FSTL1 FDA NNMT Superoxide dismutase (EC 1.15.1.1)LIF ACTH catalase (EC 1.11.1.6)glutathione peroxidase (EC 1.11.1.9)OXM BDNF keap1 C/EBP C/EBP homologous protein GSH-Px PPARs TZDs Ucp1 AST endocannabinoid Apoe apolipoprotein E Food and Drugs Administration Chronic low-grade inflammation insulin-like growth factor I Novel targets interferon γ interleukin White adipose tissue brown adipose tissue Triglycerides fat mass tumor necrosis factor-α CHOP thiazolidinediones Fat Free Mass Pharmacotherapy cocaine- and amphetamine-regulated transcript FTO Waist circumference Hip Circumference high-fat diet diet induced obesity World Health Organization SOD suppressors of cytokine signaling Intestinal epithelial cells Metabolic syndrome body mass index BMI leukemia inhibitory factor fibroblast growth factor 21 Brain-derived neurotrophic factor TNF-α nuclear factor kappaB Contents Arc high-density lipoprotein cholesterol PVN signal transducer and activator of transcription 3 METS Obesity Clinical studies Insulin resistance HPA Waist to height ratio Waist to hip ratio Glucose transporter type 4 Nitric oxide nucleus of the solitary tract arcuate nucleus paraventricular nucleus adrenocorticotropic hormone Melanocyte-stimulating hormone hypothalamic-pituitary-adrenal body weight Pancreatic polypeptide monocyte chemoattractant protein 1 secreted protein acidic and rich in cysteine uncoupling protein 1 Kelch-like ECH-associated protein 1 Adipocyte fatty acid-binding protein sterol regulatory element-binding proteins Retinol binding protein 4 Perilipin 1 glucagon-like peptide-1 peptide YY glucose-dependent insulinotropic peptide agouti-related peptide WAT total cholesterol Low-density lipoprotein cholesterol IECs WHO cholecystokinin GABA gamma-amino-butyric acid Medicinal plants Peroxisome proliferator-activated receptors melanocortin receptors Neuropeptide Y

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Causes and solutions to “globesity”: The new fa(s)t alarming global epidemic

Authors

Liliya V. Vasileva, Andrey S. Marchev, Milen I. Georgiev,