Structure based design of 4-(3-aminomethylphenyl)piperidinyl-1-amides: novel, potent, selective, and orally bioavailable inhibitors of βII tryptase Fulltext Access 14 Pages 2005
Determination of mycotoxins in bovine milk by liquid chromatography tandem mass spectrometry Fulltext Access 14 Pages 2005
A hybrid LC-Gel-MS method for proteomics research and its application to protease functional pathway mapping Fulltext Access 14 Pages 2005
Effects of pure n-alkanes and crude oil on bacterial phospholipid classes and molecular species determined by electrospray ionization mass spectrometry Fulltext Access 14 Pages 2005
Validation and implementation of a liquid chromatography/tandem mass spectrometry assay to quantitate dimethyl benzoylphenylurea (BPU) and its five metabolites in human plasma and urine for clinical pharmacology studies Fulltext Access 14 Pages 2005
Synthesis and biological evaluation of new symmetrical derivatives as cytotoxic agents and apoptosis inducers Fulltext Access 14 Pages 2005
Role of proteomics in taxonomy: the Mytilus complex as a model of study Fulltext Access 14 Pages 2005
Synthesis and inhibitory activity of benzoic acid and pyridine derivatives on influenza neuraminidase Fulltext Access 14 Pages 2005
Lysine–spermine conjugates: hydrophobic polyamine amides as potent lipopolysaccharide sequestrants Fulltext Access 14 Pages 2005
Synthesis of potent and selective inhibitors of Candida albicans N-myristoyltransferase based on the benzothiazole structure Fulltext Access 14 Pages 2005
Synthesis of 13C-labeled γ-hydroxybutyrates for EPR studies with 4-hydroxybutyryl-CoA dehydratase Fulltext Access 14 Pages 2005
Synthesis and pharmacological evaluation of benzamide derivatives as selective 5-HT4 receptor agonists Fulltext Access 14 Pages 2005
1-Substituted pyrazolo[1,5-c]quinazolines as novel Gly/NMDA receptor antagonists: Synthesis, biological evaluation, and molecular modeling study Fulltext Access 14 Pages 2005
Insight into 2-phenylpyrazolo[1,5-a]pyrimidin-3-yl acetamides as peripheral benzodiazepine receptor ligands: Synthesis, biological evaluation and 3D-QSAR investigation Fulltext Access 14 Pages 2005
Application of immobilized enzyme reactor in on-line high performance liquid chromatography: A review Fulltext Access 14 Pages 2005
Recent advances in the design and construction of helical coordination polymers Fulltext Access 14 Pages 2005
Structure, solution equilibria and magnetic properties of copper(II) complexes with new sulfurated triazoline derivatives of α-amino acids Fulltext Access 14 Pages 2005
Halogenated rhenacarboranes: optoelectronic behavior of the iodinated rhenacarborane complex anion [3,3,3-(CO)3-8-I-closo-3,1,2-ReC2B9H10]â Fulltext Access 14 Pages 2005
First high-nuclearity palladium halide/carbonyl/phosphine cluster, [Pd12(μ3-I)2(μ4-I)3(μ2-CO)6(PEt3)6]+ monocation containing an octacapped octahedral Pd6(μ3-Pd)6(μ3-I)2 fragment: structure-to-synthesis generation from different synthetic routes Fulltext Access 14 Pages 2005
New reactions and new products derived from α-deprotonated Fischer-type carbene complexes Fulltext Access 14 Pages 2005
New cationic palladium (II) and rhodium (I) complexes of [Ph2PCH2C(Ph)N(2,6-Me2C6H3)] Fulltext Access 14 Pages 2005
Synthesis, characterization and Schlenk equilibrium studies of methylmagnesium compounds with O- and N-donor ligands - the unexpected behavior of [MgMeBr(pmdta)] (pmdta = N,N,Nâ²,Nâ³,Nâ³-pentamethyldiethylenetriamine) Fulltext Access 14 Pages 2005
Chemotaxonomic analysis of Astragalus caprinus (Fabaceae) based on the flavonic patterns Fulltext Access 14 Pages 2005
Tracking the source of Bacillus thuringiensis Cry1Ab endotoxin in the environment Fulltext Access 14 Pages 2005
Chalcones and other flavonoids from Asarum sensu lato (Aristolochiaceae) Fulltext Access 14 Pages 2005
Synthesis and structure of N-arylimines of β-tellurocyclohexenals with the intramolecular coordination N â Te bonds Fulltext Access 14 Pages 2005
Imino- and bis-imino-pyridines with N-ter-butyl-N-aminoxyl group: synthesis, oxidation and use as ligand towards M2+ ( Mn, Ni, Zn) and Gd3+ Fulltext Access 14 Pages 2005
Cation templation of Mn2+/[Mo(CN)7]4â system: Formation of pseudo-dimorphs (NH4)2Mn3(H2O)4[Mo(CN)7]2 · nH2O (n = 4, 5) Fulltext Access 14 Pages 2005
Synthesis, spectroscopic characterization, crystal, molecular and electronic structure of the [{ReOBr2(pyz)2}2(μ-O)] and [{ReOBr2}2(μ-O)(μ-pyd)2] complexes Fulltext Access 14 Pages 2005
Structure–affinity relationship studies of non-competitive NMDA receptor antagonists derived from dexoxadrol and etoxadrol Fulltext Access 14 Pages 2005
Hantzsch 1,4-dihydropyridines containing a diazen-1-ium-1,2-diolate nitric oxide donor moiety to study calcium channel antagonist structure-activity relationships and nitric oxide release Fulltext Access 14 Pages 2005
A new type of ketolides bearing an N-aryl-alkyl acetamide moiety at the C-9 iminoether synthesis and structure–activity relationships Fulltext Access 14 Pages 2005
Substrate specificity of the bovine serum amine oxidase and in situ characterisation of aminoaldehydes by NMR spectroscopy Fulltext Access 14 Pages 2005
Potent antitumor 9-anilinoacridines bearing an alkylating N-mustard residue on the anilino ring: synthesis and biological activity Fulltext Access 14 Pages 2005
Mechanism and structure–activity relationships of norspermidine-based peptidic inhibitors of trypanothione reductase Fulltext Access 14 Pages 2005
Bis(amino)allenylidene complexes by displacement of the MeO group in methoxy allenylidene complexes of chromium and tungsten. Synthesis, DFT calculations and solid-state structures of new bis(amino)allenylidene complexes Fulltext Access 14 Pages 2005
Diphenylcyclohexylamine derivatives as new potent multidrug resistance (MDR) modulators Fulltext Access 14 Pages 2005
α-cycloalkyl-substituted Ï-keto-dicarboxylic acids as lipid regulating agents Fulltext Access 14 Pages 2005
New bromo-, triflato-, and hydridotricarbonylrhenium(I) complexes with diphosphinite ligands: Structural, spectral and protonation studies of various hydrides Fulltext Access 14 Pages 2005
Asymmetric C–H insertion of Rh(II) stabilized carbenoids into acetals: A C–H activation protocol as a Claisen condensation equivalent Fulltext Access 14 Pages 2005
Oxidative addition of aryl chlorides to palladium N-heterocyclic carbene complexes and their role in catalytic arylamination Fulltext Access 14 Pages 2005
Formation of chiral ionic liquids and imidazol-2-ylidene metal complexes from the proteinogenic aminoacid l-histidine Fulltext Access 14 Pages 2005
Imino Diels–Alder reaction of boronates: A new route to 3,4-dihydroquinolines Fulltext Access 14 Pages 2005
Selective anti-tubercular purines: Synthesis and chemotherapeutic properties of 6-aryl- and 6-heteroaryl-9-benzylpurines Fulltext Access 14 Pages 2005
Discovery of 1,7-cyclized indoles as a new class of potent and highly selective human β3-adrenergic receptor agonists with high cell permeability Fulltext Access 14 Pages 2005
Nuclear receptor antagonists designed based on the helix-folding inhibition hypothesis Fulltext Access 14 Pages 2005
Terpene trilactones from Gingko biloba: From ancient times to the 21st century Fulltext Access 14 Pages 2005
Selective inhibitors of GABA uptake: synthesis and molecular pharmacology of 4-N-methylamino-4,5,6,7-tetrahydrobenzo[d]isoxazol-3-ol analogues Fulltext Access 14 Pages 2005
Isocoumarins as estrogen receptor beta selective ligands: Isomers of isoflavone phytoestrogens and their metabolites Fulltext Access 14 Pages 2005
QSAR modeling of blood:air and tissue:air partition coefficients using theoretical descriptors Fulltext Access 14 Pages 2005
Synthesis and pharmacological evaluation of side chain modified glutamic acid analogues of the neuroprotective agent glycyl-l-prolyl-l-glutamic acid (GPE) Fulltext Access 14 Pages 2005
Synthesis of 17β-estradiol-linked platinum(II) complexes and their cytocidal activity on estrogen-dependent and -independent breast tumor cells Fulltext Access 15 Pages 2005
Synthesis and cytotoxic activity of carboxamide derivatives of benzo[b][1,6]naphthyridin-(5H)ones Fulltext Access 15 Pages 2005
Synthesis of 4-(1-oxo-isoindoline) and 4-(5,6-dimethoxy-1-oxo-isoindoline)-substituted phenoxypropanolamines and their β1-, β2-adrenergic receptor binding studies Fulltext Access 15 Pages 2005
Synthesis and pharmacological evaluation of 4H-1,4-benzothiazine-2-carbonitrile 1,1-dioxide and N-(2-cyanomethylsulfonylphenyl)acylamide derivatives as potential activators of ATP sensitive potassium channels Fulltext Access 15 Pages 2005
Inhibitory activity of polyhydroxycarboxylate chelators against recombinant NF-κB p50 protein-DNA binding Fulltext Access 15 Pages 2005
Phylogenetic relationships between Afrotropical and Palaearctic Crocidura species inferred from Inter-SINE-PCR Fulltext Access 15 Pages 2005
The expression of the NADPH oxidase subunit p22phox is regulated by a redox-sensitive pathway in endothelial cells Fulltext Access 15 Pages 2005
N-Acyl-N-alkyl-sulfonamide anchors derived from Kenner's safety-catch linker: powerful tools in bioorganic and medicinal chemistry Fulltext Access 15 Pages 2005
Induction of endothelial cell apoptosis by lipid hydroperoxide-derived bifunctional electrophiles Fulltext Access 15 Pages 2005
The inside and outside protonation of a 15-membered O2N2-macrocycle. Synthesis and structural characterization of the protonated ligand salts Fulltext Access 15 Pages 2005
Stereoselective synthesis of E-64 and related cysteine proteases inhibitors from 2,3-epoxyamides Fulltext Access 15 Pages 2005
Concise syntheses of arabinogalactans with β-(1â6)-linked galactopyranose backbones and α-(1â3)- and α-(1â2)-linked arabinofuranose side chains Fulltext Access 15 Pages 2005
A novel class of sodium/calcium exchanger inhibitor: design, synthesis, and structure–activity relationships of 3,4-dihydro-2(1H)-quinazolinone derivatives Fulltext Access 15 Pages 2005
Self-assembly of diorganotin(IV) 2-{[(E)-1-(2-oxyaryl)alkylidene]amino}acetates: An investigation of structures by X-ray diffraction, solution and solid-state tin NMR, and electrospray ionization MS Fulltext Access 15 Pages 2005
Catalytic dehydrogenation of cyclooctane with titanium, zirconium and hafnium metallocene complexes Fulltext Access 15 Pages 2005
Synthesis and property of BrCCH- and BrCCBr-coordinated tetrairon clusters Fulltext Access 15 Pages 2005
Metal-containing ionic liquids and ionic liquid crystals based on imidazolium moiety Fulltext Access 15 Pages 2005
Olefin metathesis in room temperature ionic liquids using imidazolium-tagged ruthenium complexes Fulltext Access 15 Pages 2005
Trifluoroethanol: key solvent for palladium-catalyzed polymerization reactions Fulltext Access 15 Pages 2005
Discovery of an N-(2-aminopyridin-4-ylmethyl)nicotinamide derivative: a potent and orally bioavailable NCX inhibitor Fulltext Access 15 Pages 2005
Structure activity studies of the serine-AIB dipeptide domain in 2,3-dihydroisothiazole based growth hormone secretagogues Fulltext Access 15 Pages 2005
Molecular modeling, design, synthesis, and biological evaluation of novel 3′,4′-dicamphanoyl-(+)-cis-khellactone (DCK) analogs as potent anti-HIV agents Fulltext Access 15 Pages 2005
C3′-cis-Substituted carboxycyclopropyl glycines as metabotropic glutamate 2/3 receptor agonists: Synthesis and SAR studies Fulltext Access 15 Pages 2005
Synthesis, solution structure, and bioactivity of six new simplified analogues of the natural cyclodepsipeptide jaspamide Fulltext Access 15 Pages 2005
Complexes derived from hydrolytically 'unstable' hydrazone ligands - Some unexpected products Fulltext Access 15 Pages 2005
Novel 3-amino-2-hydroxy acids containing protease inhibitors. Part 1: Synthesis and kinetic characterization as aminopeptidase P inhibitors Fulltext Access 15 Pages 2005
2,9-Disubstituted-N6-(arylcarbamoyl)-8-azaadenines as new selective A3 adenosine receptor antagonists: Synthesis, biochemical and molecular modelling studies Fulltext Access 15 Pages 2005
Two novel series of allocolchicinoids with modified seven membered B-rings: design, synthesis, inhibition of tubulin assembly and cytotoxicity Fulltext Access 15 Pages 2005
Structure–activity relationships and molecular modelling of 5-arylidene-2,4-thiazolidinediones active as aldose reductase inhibitors Fulltext Access 15 Pages 2005
A physically interpretable quantum-theoretic QSAR for some carbonic anhydrase inhibitors with diverse aromatic rings, obtained by a new QSAR procedure Fulltext Access 15 Pages 2005
Copolymerization of ethylene/unsaturated alcohols using nickel catalysts: effect of the ligand on the activity and comonomer incorporation Fulltext Access 15 Pages 2005
Preparation of α-substituted γ-alkoxyallylstannanes from β-tributylstannyl acrolein acetals: scope of the method and primary rationalization of the obtained results Fulltext Access 15 Pages 2005
Syntheses, crystal structures and coordination modes of tri- and di-organotin derivatives with 2-mercapto-4-methylpyrimidine Fulltext Access 15 Pages 2005
4-Silapiperidine and 4-silapiperidinium derivatives: syntheses and structural characterization Fulltext Access 15 Pages 2005
New syntheses of ansa-metallocenes or unbridged substituted metallocenes by the respective reductive dimerization of fulvenes with Group 4 metal divalent halides or with Group 4 metal dichloride dihydrides Fulltext Access 15 Pages 2005