Depletion of Rab32 decreases intracellular lipid accumulation and induces lipolysis through enhancing ATGL expression in hepatocytes Fulltext Access 18 Pages 2016
Conformational modulation mediated by polyglutamine expansion in CAG repeat expansion disease-associated proteins Fulltext Access 18 Pages 2016
An ultrasensitive assay format for detecting ULK1 inhibition by monitoring the phosphorylation status of Atg13 Fulltext Access 18 Pages 2016
Phenotyping hepatocellular metabolism using uniformly labeled carbon-13 molecular probes and LC-HRMS stable isotope tracing Fulltext Access 18 Pages 2016
AT13148, a first-in-class multi-AGC kinase inhibitor, potently inhibits gastric cancer cells both in vitro and in vivo Fulltext Access 18 Pages 2016
Activation of mPTP-dependent mitochondrial apoptosis pathway by a novel pan HDAC inhibitor resminostat in hepatocellular carcinoma cells Fulltext Access 18 Pages 2016
Long non-coding RNA TUG1 acts as a miR-26a sponge in human glioma cells Fulltext Access 18 Pages 2016
RNA interference targeting CYP76AH1 in hairy roots of Salvia miltiorrhiza reveals its key role in the biosynthetic pathway of tanshinones Fulltext Access 18 Pages 2016
Efficient biallelic mutation in porcine parthenotes using a CRISPR-Cas9 system Fulltext Access 18 Pages 2016
The role of Wnt regulation in heart development, cardiac repair and disease: A tissue engineering perspective Fulltext Access 18 Pages 2016
Cyp1b1 affects external control of mouse hepatocytes, fatty acid homeostasis and signaling involving HNF4α and PPARα Fulltext Access 18 Pages 2016
Noninvasive diagnosis and monitoring of mutations by deep sequencing of circulating tumor DNA in esophageal squamous cell carcinoma Fulltext Access 18 Pages 2016
Neuroprotective effects of Wnt/β-catenin signaling pathway against Aβ -induced tau protein over-phosphorylation in PC12 cells Fulltext Access 18 Pages 2016
A bispecific antibody (ScBsAbAgn-2/TSPO) target for Ang-2 and TSPO resulted in therapeutic effects against glioblastomas Fulltext Access 18 Pages 2016
Targeting colorectal cancer cells by a novel sphingosine kinase 1 inhibitor PF-543 Fulltext Access 18 Pages 2016
Trichostatin A enhances estrogen receptor-alpha repression in MCF-7 breast cancer cells under hypoxia Fulltext Access 18 Pages 2016
Involvement of the Lhcx protein Fcp6 of the diatom Cyclotella meneghiniana in the macro-organisation and structural flexibility of thylakoid membranes Fulltext Access 18 Pages 2016
En route from artificial to natural: Evaluation of inhibitors of mannose-specific adhesion of E. coli under flow Fulltext Access 18 Pages 2016
Structure and function of α-crystallins: Traversing from in vitro to in vivo Fulltext Access 18 Pages 2016
Ferrous iron and α-ketoglutarate-dependent dioxygenases in the biosynthesis of microbial natural products Fulltext Access 18 Pages 2016
SC79 rescues osteoblasts from dexamethasone though activating Akt-Nrf2 signaling Fulltext Access 18 Pages 2016
3β-Hydroxy-urs-12-en-28-oic acid prolongs lifespan in C. elegans by modulating JNK-1 Fulltext Access 18 Pages 2016
GSK621 activates AMPK signaling to inhibit LPS-induced TNFα production Fulltext Access 18 Pages 2016
mTOR inhibition sensitizes ONC201-induced anti-colorectal cancer cell activity Fulltext Access 18 Pages 2016
Rational design of liposomal drug delivery systems, a review: Combined experimental and computational studies of lipid membranes, liposomes and their PEGylation Fulltext Access 19 Pages 2016
Inward open characterization of EmrD transporter with molecular dynamics simulation Fulltext Access 19 Pages 2016
A combination of luxR1 and luxR2 genes activates Pr-promoters of psychrophilic Aliivibrio logei lux-operon independently of chaperonin GroEL/ES and protease Lon at high concentrations of autoinducer Fulltext Access 19 Pages 2016
Targeting of the human F8 at the multicopy rDNA locus in Hemophilia a patient-derived iPSCs using TALENickases Fulltext Access 19 Pages 2016
Phosphatase and tensin homologue (PTEN)-induced putative kinase 1 reduces pancreatic β-cells apoptosis in glucotoxicity through activation of autophagy Fulltext Access 19 Pages 2016
MicroRNA-126 increases chemosensitivity in drug-resistant gastric cancer cells by targeting EZH2 Fulltext Access 19 Pages 2016
Exogenous S100A8 protein inhibits PDGF-induced migration of airway smooth muscle cells in a RAGE-dependent manner Fulltext Access 19 Pages 2016
Heterologous gene expression and functional analysis of a type III polyketide synthase from Aspergillus niger NRRL 328 Fulltext Access 19 Pages 2016
Alpha-synuclein activates BV2 microglia dependent on its aggregation state Fulltext Access 19 Pages 2016
An integrated wave modelling framework for extreme and rare events for climate change in coastal areas – the case of Rethymno, Crete Fulltext Access 19 Pages 2016
TAGLN2, a novel regulator involved in Hepatitis B virus transcription and replication Fulltext Access 19 Pages 2016
Hit 'em where it hurts: The growing and structurally diverse family of peptides that target lipid-II Fulltext Access 19 Pages 2016
CD147 induces up-regulation of vascular endothelial growth factor in U937-derived foam cells through PI3K/AKT pathway Fulltext Access 19 Pages 2016
Autophagy prevention sensitizes AKTi-1/2-induced anti-hepatocellular carcinoma cell activity in vitro and in vivo Fulltext Access 19 Pages 2016
Therapeutic efficacy of an anti-PD-L1 antibody based immunocytokine in a metastatic mouse model of colorectal cancer Fulltext Access 19 Pages 2016
Long non-coding RNA CCAT1 promotes glioma cell proliferation via inhibiting microRNA-410 Fulltext Access 19 Pages 2016
TRPV4 is endogenously expressed in vertebrate spermatozoa and regulates intracellular calcium in human sperm Fulltext Access 19 Pages 2016
Downregulated long non-coding RNA MEG3 in breast cancer regulates proliferation, migration and invasion by depending on p53's transcriptional activity Fulltext Access 19 Pages 2016
Application of histogram analysis for the evaluation of vascular permeability in glioma by the K2 parameter obtained with the dynamic susceptibility contrast method: Comparisons with Ktrans obtained with the dynamic contrast enhance method and cerebral bl Fulltext Access 19 Pages 2016
Hydrophobic interactions between the S5 segment and the pore helix stabilizes the closed state of Slo2.1 potassium channels Fulltext Access 19 Pages 2016
Hydrated nonpolar solute volumes: Interplay between size, Attractiveness, and molecular structure Fulltext Access 19 Pages 2016
Activation of the Wnt/β-catenin pathway in pancreatic beta cells during the compensatory islet hyperplasia in prediabetic mice Fulltext Access 19 Pages 2016
Survival fraction and phenotype alterations of Xenopus laevis embryos at 3Â Gy, 150Â kV X-ray irradiation Fulltext Access 20 Pages 2016
Activating AMP-activated protein kinase by an α1 selective activator compound 13 attenuates dexamethasone-induced osteoblast cell death Fulltext Access 20 Pages 2016
miR-320a regulates cell proliferation and apoptosis in multiple myeloma by targeting pre-B-cell leukemia transcription factor 3 Fulltext Access 20 Pages 2016
Identification of the Raptor-binding motif on Arabidopsis S6 kinase and its use as a TOR signaling suppressor Fulltext Access 20 Pages 2016
RIP3-dependent necrosis induced inflammation exacerbates atherosclerosis Fulltext Access 20 Pages 2016
iTRAQ-based chromatin proteomic screen reveals CHD4-dependent recruitment of MBD2 to sites of DNA damage Fulltext Access 20 Pages 2016
Mefloquine effectively targets gastric cancer cells through phosphatase-dependent inhibition of PI3K/Akt/mTOR signaling pathway Fulltext Access 20 Pages 2016
Dipeptidyl peptidase-4 inhibitor MK-626 restores insulin secretion through enhancing autophagy in high fat diet-induced mice Fulltext Access 20 Pages 2016
Ikaros limits follicular B cell activation by regulating B cell receptor signaling pathways Fulltext Access 20 Pages 2016
13C kinetic isotope effects on the reaction of a flavin amine oxidase determined from whole molecule isotope effects Fulltext Access 20 Pages 2016
Targeting of the BLT2 in chronic myeloid leukemia inhibits leukemia stem/progenitor cell function Fulltext Access 20 Pages 2016
Hepatic FTO expression is increased in NASH and its silencing attenuates palmitic acid-induced lipotoxicity Fulltext Access 20 Pages 2016
Long non-coding RNA HOTAIR promotes ischemic infarct induced by hypoxia through up-regulating the expression of NOX2 Fulltext Access 20 Pages 2016
pySAPC, a python package for sparse affinity propagation clustering: Application to odontogenesis whole genome time series gene-expression data Fulltext Access 20 Pages 2016
Identification of pyrrolo[3,2-c]pyridin-4-amine compounds as a new class of entry inhibitors against influenza viruses in vitro Fulltext Access 20 Pages 2016
miR-625 suppresses cell proliferation and migration by targeting HMGA1 in breast cancer Fulltext Access 20 Pages 2016
Modeling, molecular docking, probing catalytic binding mode of acetyl-CoA malate synthase G in Brucella melitensis 16M Fulltext Access 20 Pages 2016
Overexpression of GhSARP1 encoding a E3 ligase from cotton reduce the tolerance to salt in transgenic Arabidopsis Fulltext Access 20 Pages 2016
Endoplasmic reticulum-mitochondrial interaction mediated by mitofusin-1 or mitofusin-2 is not required for lipid droplet formation or adipocyte differentiation Fulltext Access 20 Pages 2016
Arsenic and 17-β-estradiol bind to each other and neutralize each other's signaling effects Fulltext Access 20 Pages 2016
Open reading frames 1a and 1b of the porcine reproductive and respiratory syndrome virus (PRRSV) collaboratively initiate viral minus-strand RNA synthesis Fulltext Access 20 Pages 2016
GLP-1 analogue improves hepatic lipid accumulation by inducing autophagy via AMPK/mTOR pathway Fulltext Access 20 Pages 2016
Pluripotency induction in HEK293T cells by concurrent expression of STELLA, OCT4 and NANOS2 Fulltext Access 20 Pages 2016
Molecular evidence for the coordination of nitrogen and carbon metabolisms, revealed by a study on the transcriptional regulation of the agl3EFG operon that encodes a putative carbohydrate transporter in Streptomyces coelicolor Fulltext Access 20 Pages 2016
A novel, rapid and efficient method of cloning functional antigen-specific T-cell receptors from single human and mouse T-cells Fulltext Access 20 Pages 2016
Crystal structures of Staphylococcal SaeR reveal possible DNA-binding modes Fulltext Access 20 Pages 2016
Evaluating the stability of pharmacophore features using molecular dynamics simulations Fulltext Access 21 Pages 2016
MAPK13 is preferentially expressed in gynecological cancer stem cells and has a role in the tumor-initiation Fulltext Access 21 Pages 2016
Type 1 5â²-deiodinase activity is inhibited by oxidative stress and restored by alpha-lipoic acid in HepG2 cells Fulltext Access 21 Pages 2016
Vesicular monoamine transporter 2 (Vmat2) knockdown elicits anxiety-like behavior in zebrafish Fulltext Access 21 Pages 2016
Long noncoding RNA H19 regulates EZH2 expression by interacting with miR-630 and promotes cell invasion in nasopharyngeal carcinoma Fulltext Access 21 Pages 2016
Carvedilol promotes mitochondrial biogenesis by regulating the PGC-1/TFAM pathway in human umbilical vein endothelial cells (HUVECs) Fulltext Access 21 Pages 2016
Expanded polyglutamine embedded in the endoplasmic reticulum causes membrane distortion and coincides with Bax insertion Fulltext Access 21 Pages 2016
Toll-like receptor-6 (TLR6) deficient mice are protected from myocardial fibrosis induced by high fructose feeding through anti-oxidant and inflammatory signaling pathway Fulltext Access 21 Pages 2016
Anisomycin-induced GATA-6 degradation accompanying a decrease of proliferation of colorectal cancer cell Fulltext Access 21 Pages 2016
Co-transforming bar and CsLEA enhanced tolerance to drought and salt stress in transgenic alfalfa (Medicago sativa L.) Fulltext Access 21 Pages 2016
Neuroprotective effect of sulfated polysaccharide isolated from sea cucumber Stichopus japonicus on 6-OHDA-induced death in SH-SY5Y through inhibition of MAPK and NF-κB and activation of PI3K/Akt signaling pathways Fulltext Access 21 Pages 2016
Licoflavonol is an inhibitor of the type three secretion system of Salmonella enterica serovar Typhimurium Fulltext Access 21 Pages 2016
Circular RNA expression alterations are involved in OGD/R-induced neuron injury Fulltext Access 21 Pages 2016
RETRACTED: Ghrelin protects infarcted myocardium by induction of autophagy and AMP-activated protein kinase pathway Fulltext Access 21 Pages 2016