Knockdown of fascin-1 expression suppresses cell migration and invasion of non-small cell lung cancer by regulating the MAPK pathway Fulltext Access 6 Pages 2018
Dual inhibition of mTORC1 and mTORC2 perturbs cytoskeletal organization and impairs endothelial cell elongation Fulltext Access 6 Pages 2018
Detection of substrate binding of a collagen-specific molecular chaperone HSP47 in solution using fluorescence correlation spectroscopy Fulltext Access 6 Pages 2018
Snapshots of catalysis: Structure of covalently bound substrate trapped in Mycobacterium tuberculosis thiazole synthase (ThiG) Fulltext Access 6 Pages 2018
miR-199a-5p inhibits the progression of papillary thyroid carcinoma by targeting SNAI1 Fulltext Access 6 Pages 2018
Establishment of mouse gingival junctional epithelial cell line using a bioengineered tooth system Fulltext Access 6 Pages 2018
Quantitative monitoring of two simultaneously binding species using Label-Enhanced surface plasmon resonance Fulltext Access 6 Pages 2018
The UBA domain of SnRK1 promotes activation and maintains catalytic activity Fulltext Access 6 Pages 2018
Biosynthetic machinery for C25,C25-diether archaeal lipids from the hyperthermophilic archaeon Aeropyrum pernix Fulltext Access 6 Pages 2018
Pol I DNA polymerases stimulate DNA end-joining by Escherichia coli DNA ligase Fulltext Access 6 Pages 2018
Neurokinin B and serum albumin limit copper binding to mammalian gonadotropin releasing hormone Fulltext Access 6 Pages 2018
Crystal structure of a substrate-binding protein from Rhodothermus marinus reveals a single α/β-domain Fulltext Access 6 Pages 2018
Increased cerebrospinal fluid complement C5 levels in major depressive disorder and schizophrenia Fulltext Access 6 Pages 2018
The C2â²- and C3â²-endo equilibrium for AMP molecules bound in the cystathionine-beta-synthase domain Fulltext Access 6 Pages 2018
GATA3 acetylation at K119 by CBP inhibits cell migration and invasion in lung adenocarcinoma Fulltext Access 6 Pages 2018
Activation of calcium-sensing receptor-mediated autophagy in angiotensinII-induced cardiac fibrosis in vitro Fulltext Access 6 Pages 2018
GhoT of the GhoT/GhoS toxin/antitoxin system damages lipid membranes by forming transient pores Fulltext Access 6 Pages 2018
Serum levels of IL-17 are elevated in patients with acute gouty arthritis Fulltext Access 6 Pages 2018
Polyphyllin I inhibits gastric cancer cell proliferation by downregulating the expression of fibroblast activation protein alpha (FAP) and hepatocyte growth factor (HGF) in cancer-associated fibroblasts Fulltext Access 6 Pages 2018
A unified mechanism for plant polyketide biosynthesis derived from in silico modeling Fulltext Access 6 Pages 2018
Disruption of LRRK2 in Zebrafish leads to hyperactivity and weakened antibacterial response Fulltext Access 6 Pages 2018
Crystal structure of heat shock protein 15 (Hsp15) from Vibrio cholerae: Novel mode of trimerization and nucleic acid binding properties Fulltext Access 6 Pages 2018
Splicing activator RNPS1 suppresses errors in pre-mRNA splicing: A key factor for mRNA quality control Fulltext Access 6 Pages 2018
Cloning and functional characterization of a p-coumaroyl quinate/shikimate 3â²-hydroxylase from potato (Solanum tuberosum) Fulltext Access 6 Pages 2018
Binding of PICK1 PDZ domain with calcineurin B regulates osteoclast differentiation Fulltext Access 6 Pages 2018
Fenofibrate inhibits mTOR-p70S6K signaling and simultaneously induces cell death in human prostate cancer cells Fulltext Access 6 Pages 2018
Keratin 13 gene is epigenetically suppressed during transforming growth factor-β1-induced epithelial-mesenchymal transition in a human keratinocyte cell line Fulltext Access 6 Pages 2018
Escherichia coli single-stranded DNA binding protein SSB promotes AlkB-mediated DNA dealkylation repair Fulltext Access 6 Pages 2018
The pathogenic role of MEF2D-SS18 fusion gene in B-cell acute lymphoblastic leukemia Fulltext Access 6 Pages 2018
Transient activation of Wnt/β-catenin signaling reporter in fibrotic scar formation after compression spinal cord injury in adult mice Fulltext Access 6 Pages 2018
The protective effect of nicorandil on cardiomyocyte apoptosis after coronary microembolization by activating Nrf2/HO-1 signaling pathway in rats Fulltext Access 6 Pages 2018
Overstretching partially alkyne functionalized dsDNA using near infrared optical tweezers Fulltext Access 6 Pages 2018
Piperlongumine and some of its analogs inhibit selectively the human immunoproteasome over the constitutive proteasome Fulltext Access 6 Pages 2018
Tamoxifen activates hypothalamic l-dopa synthesis to stimulate ovarian estrogen production in chicken Fulltext Access 6 Pages 2018
Low levels of TSC22 enhance tumorigenesis by inducing cell proliferation in colorectal cancer Fulltext Access 6 Pages 2018
Secretion of GLP-1 but not GIP is potently stimulated by luminal d-Allulose (d-Psicose) in rats Fulltext Access 6 Pages 2018
Preservation of rat hearts in subfreezing temperature isochoric conditions to - 8â¯Â°C and 78â¯MPa Fulltext Access 6 Pages 2018
The level of decoy epitope in PCV2 vaccine affects the neutralizing activity of sera in the immunized animals Fulltext Access 6 Pages 2018
Use of CK-548 and CK-869 as Arp2/3 complex inhibitors directly suppresses microtubule assembly both in vitro and in vivo Fulltext Access 6 Pages 2018
KSHV vIRF4 enhances BCL6 transcription via downregulation of IRF4 expression Fulltext Access 6 Pages 2018
Characterization of human ATP-binding cassette protein subfamily D reconstituted into proteoliposomes Fulltext Access 6 Pages 2018
The interaction between calcineurin and α-synuclein is regulated by calcium and calmodulin Fulltext Access 6 Pages 2018
Casein kinase 2 phosphorylates and stabilizes C/EBPβ in pancreatic β cells Fulltext Access 6 Pages 2018
Characterisation of the biological response of Saccharomyces cerevisiae to the loss of an allele of the eukaryotic initiation factor 4A Fulltext Access 6 Pages 2018
General misincorporation frequency: Re-evaluation of the fidelity of DNA polymerases Fulltext Access 6 Pages 2018
High expression of A-type lamin in the leading front is required for Drosophila thorax closure Fulltext Access 6 Pages 2018
Oncostatin M induces tumorigenic properties in non-transformed human prostate epithelial cells, in part through activation of signal transducer and activator of transcription 3 (STAT3) Fulltext Access 6 Pages 2018
Establishment of the cross-clade antigen detection system for H5 subtype influenza viruses using peptide monoclonal antibodies specific for influenza virus H5 hemagglutinin Fulltext Access 6 Pages 2018
Djhsp90s are crucial regulators during planarian regeneration and tissue homeostasis Fulltext Access 6 Pages 2018
Protective effect of ALDH2 against cyclophosphamide-induced acute hepatotoxicity via attenuating oxidative stress and reactive aldehydes Fulltext Access 6 Pages 2018
Protective effects of kenpaullone on cardiomyocytes following H2O2-induced oxidative stress are attributed to inhibition of connexin 43 degradation by SGSM3 Fulltext Access 6 Pages 2018
Reactive oxygen species participate in liver function recovery during compensatory growth in zebrafish (Danio rerio) Fulltext Access 6 Pages 2018
Interleukin-23 promotes the migration and invasion of gastric cancer cells by inducing epithelial-to-mesenchymal transition via the STAT3 pathway Fulltext Access 6 Pages 2018
Liraglutide attenuates NLRP3 inflammasome-dependent pyroptosis via regulating SIRT1/NOX4/ROS pathway in H9c2 cells Fulltext Access 6 Pages 2018
Loop engineering reveals the importance of active-site-decorating loops and gating residue in substrate affinity modulation of arginine deiminase (an anti-tumor enzyme) Fulltext Access 6 Pages 2018
The blocking of aquaporin-3 (AQP3) impairs extravillous trophoblast cell migration Fulltext Access 6 Pages 2018
Leucokinin signaling regulates hunger-driven reduction of behavioral responses to noxious heat in Drosophila Fulltext Access 6 Pages 2018
The guanine nucleotide-binding protein α subunit protein ChGnaq positively regulates Hsc70 transcription in Crassostrea hongkongensis Fulltext Access 6 Pages 2018
A potential risk factor of essential hypertension in case-control study: Circular RNA hsa_circ_0037911 Fulltext Access 6 Pages 2018
Genetic overexpression of COMP-Ang1 impairs BM microenvironment and induces senescence of BM HSCs Fulltext Access 6 Pages 2018
Arginase controls soluble vascular endothelial growth factor receptor 1 (sFlt1) to maintain pregnancy homeostasis Fulltext Access 6 Pages 2018
Isolation and identification of two new alleles of STICHEL in Arabidopsis Fulltext Access 6 Pages 2018
The crystal structure and oligomeric form of Escherichia colil,d-carboxypeptidase A Fulltext Access 6 Pages 2018
Radiation resistance of the lung adenocarcinoma is related to the AKT-Onzin-POU5F1 axis Fulltext Access 6 Pages 2018
Circular RNA circC3P1 suppresses hepatocellular carcinoma growth and metastasis through miR-4641/PCK1 pathway Fulltext Access 6 Pages 2018
PIL5 represses floral transition in Arabidopsis under long day conditions Fulltext Access 6 Pages 2018
Arginase overexpression and NADPH oxidase stimulation underlie impaired vasodilation induced by advanced glycation end products Fulltext Access 6 Pages 2018
Altered metabolism of synthetic cannabinoid JWH-018 by human cytochrome P450 2C9 and variants Fulltext Access 6 Pages 2018
First description of a novel mitochondrial mutation in the MT-TI gene associated with multiple mitochondrial DNA deletion and depletion in family with severe dilated mitochondrial cardiomyopathy Fulltext Access 6 Pages 2018
Cytochrome C oxydase deficiency: SURF1 gene investigation in patients with Leigh syndrome Fulltext Access 6 Pages 2018
Cell endogenous activities of fukutin and FKRP coexist with the ribitol xylosyltransferase, TMEM5 Fulltext Access 6 Pages 2018
A missense mutation in the plasminogen gene, within the plasminogen kringle 3 domain, in hereditary angioedema with normal C1 inhibitor Fulltext Access 6 Pages 2018
Stereoselective effects of lactate enantiomers on the enhancement of 3T3-L1 adipocyte differentiation Fulltext Access 6 Pages 2018
Physiological validation of photochemical reflectance index (PRI) as a photosynthetic parameter using Arabidopsis thaliana mutants Fulltext Access 6 Pages 2018
Effects of doxorubicin on sperm DNA methylation in mouse models of testicular toxicity Fulltext Access 6 Pages 2018
A rat model of SHPT with bone abnormalities in CKD induced by adenine and a high phosphorus diet Fulltext Access 6 Pages 2018
AMPK activation by pterostilbene contributes to suppression of hepatic gluconeogenic gene expression and glucose production in H4IIE cells Fulltext Access 6 Pages 2018
Protective effect of methylallyl sulfone in the development of cigarette smoke extract-induced apoptosis in rats and HFL-1 cells Fulltext Access 6 Pages 2018
Short-term mastication after weaning upregulates GABAergic signalling and reduces dendritic spine in thalamus Fulltext Access 6 Pages 2018
Cytochalasin E increased the sensitivity of human lung cancer A549â¯cells to bortezomib via inhibition of autophagy Fulltext Access 6 Pages 2018
The anti-tumor effect of ginsenoside Rh4 in MCF-7 breast cancer cells in vitro and in vivo Fulltext Access 6 Pages 2018
Overexpression of a novel transcriptional repressor GmMYB3a negatively regulates salt-alkali tolerance and stress-related genes in soybean Fulltext Access 6 Pages 2018
Knockdown of survivin results in inhibition of epithelial to mesenchymal transition in retinal pigment epithelial cells by attenuating the TGFβ pathway Fulltext Access 6 Pages 2018
The inhibitory effect of Cordycepin on the proliferation of cisplatin-resistant A549 lung cancer cells Fulltext Access 6 Pages 2018
Enrichment of glioma stem cell-like cells on 3D porous scaffolds composed of different extracellular matrix Fulltext Access 6 Pages 2018
Loquacious-PD removes phosphate inhibition of Dicer-2 processing of hairpin RNAs into siRNAs Fulltext Access 6 Pages 2018
RD-05, a novel anti-CD154 antibody, efficiently inhibits generation of anti-drug antibody without the risk of thrombus formation in non-human primates Fulltext Access 6 Pages 2018
Deficiency of voltage-gated proton channel Hv1 attenuates streptozotocin-induced β-cell damage Fulltext Access 6 Pages 2018
Arabidopsis non-TZF gene AtC3H17 functions as a positive regulator in salt stress response Fulltext Access 6 Pages 2018
An FBXO40 knockout generated by CRISPR/Cas9 causes muscle hypertrophy in pigs without detectable pathological effects Fulltext Access 6 Pages 2018
Inhibiting 6-phosphogluconate dehydrogenase reverses doxorubicin resistance in anaplastic thyroid cancer via inhibiting NADPH-dependent metabolic reprogramming Fulltext Access 6 Pages 2018
Z-FL-COCHO, a cathepsin S inhibitor, enhances oxaliplatin-induced apoptosis through upregulation of Bim expression Fulltext Access 6 Pages 2018