Cotranslocational Degradation Protects the Stressed Endoplasmic Reticulum from Protein Overload Fulltext Access 13 Pages 2006
C. elegans SIR-2.1 Interacts with 14-3-3 Proteins to Activate DAF-16 and Extend Life Span Fulltext Access 13 Pages 2006
EphB Receptors Coordinate Migration and Proliferation in the Intestinal Stem Cell Niche Fulltext Access 13 Pages 2006
An Allosteric Mechanism for Activation of the Kinase Domain of Epidermal Growth Factor Receptor Fulltext Access 13 Pages 2006
Nef-Mediated Suppression of T Cell Activation Was Lost in a Lentiviral Lineage that Gave Rise to HIV-1 Fulltext Access 13 Pages 2006
Blimp1 Defines a Progenitor Population that Governs Cellular Input to the Sebaceous Gland Fulltext Access 13 Pages 2006
Real-Time Observation of RecA Filament Dynamics with Single Monomer Resolution Fulltext Access 13 Pages 2006
FOXP3 Controls Regulatory T Cell Function through Cooperation with NFAT Fulltext Access 13 Pages 2006
Distinct Ubiquitin-Ligase Complexes Define Convergent Pathways for the Degradation of ER Proteins Fulltext Access 13 Pages 2006
Regulation of Body Pigmentation by the Abdominal-B Hox Protein and Its Gain and Loss in Drosophila Evolution Fulltext Access 13 Pages 2006
Comparative Oncogenomics Identifies NEDD9 as a Melanoma Metastasis Gene Fulltext Access 13 Pages 2006
Cleavage at the Caspase-6 Site Is Required for Neuronal Dysfunction and Degeneration Due to Mutant Huntingtin Fulltext Access 13 Pages 2006
The Crystal Structure of the Exon Junction Complex Reveals How It Maintains a Stable Grip on mRNA Fulltext Access 13 Pages 2006
A C. elegans Model of Nicotine-Dependent Behavior: Regulation by TRP-Family Channels Fulltext Access 13 Pages 2006
A Dynamic Epicardial Injury Response Supports Progenitor Cell Activity during Zebrafish Heart Regeneration Fulltext Access 13 Pages 2006
Distinct Behavioral Responses to Ethanol Are Regulated by Alternate RhoGAP18B Isoforms Fulltext Access 13 Pages 2006
Presenilin-Dependent ErbB4 Nuclear Signaling Regulates the Timing of Astrogenesis in the Developing Brain Fulltext Access 13 Pages 2006
Tcf3 Governs Stem Cell Features and Represses Cell Fate Determination in Skin Fulltext Access 13 Pages 2006
SIN1/MIP1 Maintains rictor-mTOR Complex Integrity and Regulates Akt Phosphorylation and Substrate Specificity Fulltext Access 13 Pages 2006
Deubiquitinating Enzyme Ubp6 Functions Noncatalytically to Delay Proteasomal Degradation Fulltext Access 13 Pages 2006
A Dynamically Localized Protease Complex and a Polar Specificity Factor Control a Cell Cycle Master Regulator Fulltext Access 13 Pages 2006
Innate Immunity Gone Awry: Linking Microbial Infections to Chronic Inflammation and Cancer Fulltext Access 13 Pages 2006
A Global Map of p53 Transcription-Factor Binding Sites in the Human Genome Fulltext Access 13 Pages 2006
Ephrin-B2 Controls Cell Motility and Adhesion during Blood-Vessel-Wall Assembly Fulltext Access 13 Pages 2006
Embryonic Dorsal-Ventral Signaling: Secreted Frizzled-Related Proteins as Inhibitors of Tolloid Proteinases Fulltext Access 13 Pages 2006
Identification of a Bacterial Type III Effector Family with G Protein Mimicry Functions Fulltext Access 13 Pages 2006
Virus-Induced Abl and Fyn Kinase Signals Permit Coxsackievirus Entry through Epithelial Tight Junctions Fulltext Access 13 Pages 2006
Structure of DDB1 in Complex with a Paramyxovirus V Protein: Viral Hijack of a Propeller Cluster in Ubiquitin Ligase Fulltext Access 13 Pages 2006
The Crystal Structure of Yeast Protein Disulfide Isomerase Suggests Cooperativity between Its Active Sites Fulltext Access 13 Pages 2006
Genome-wide Prediction of Mammalian Enhancers Based on Analysis of Transcription-Factor Binding Affinity Fulltext Access 13 Pages 2006
The E3 Ubiquitin Ligase Itch Couples JNK Activation to TNFα-induced Cell Death by Inducing c-FLIPL Turnover Fulltext Access 13 Pages 2006
Endoplasmic Reticulum Stress Activates Cleavage of CREBH to Induce a Systemic Inflammatory Response Fulltext Access 13 Pages 2006
Measurement of Conformational Changes accompanying Desensitization in an Ionotropic Glutamate Receptor Fulltext Access 13 Pages 2006
Bruno Acts as a Dual Repressor of oskar Translation, Promoting mRNA Oligomerization and Formation of Silencing Particles Fulltext Access 13 Pages 2006
Asymmetric Segregation of the Tumor Suppressor Brat Regulates Self-Renewal in Drosophila Neural Stem Cells Fulltext Access 13 Pages 2006
Crystal Structure of the Ubiquitin Binding Domains of Rabex-5 Reveals Two Modes of Interaction with Ubiquitin Fulltext Access 13 Pages 2006
A Genetic Screen Implicates miRNA-372 and miRNA-373 As Oncogenes in Testicular Germ Cell Tumors Fulltext Access 13 Pages 2006
Cyld Inhibits Tumor Cell Proliferation by Blocking Bcl-3-Dependent NF-κB Signaling Fulltext Access 13 Pages 2006
A Landmark Protein Essential for Establishing and Perpetuating the Polarity of a Bacterial Cell Fulltext Access 13 Pages 2006
Ligands for Clathrin-Mediated Endocytosis Are Differentially Sorted into Distinct Populations of Early Endosomes Fulltext Access 13 Pages 2006
CRIg: A Macrophage Complement Receptor Required for Phagocytosis of Circulating Pathogens Fulltext Access 13 Pages 2006
Surface-induced changes in protein adsorption and implications for cellular phenotypic responses to surface interaction Fulltext Access 13 Pages 2006
Strategies and results of atomic force microscopy in the study of cellular adhesion Fulltext Access 13 Pages 2006
The orientation effect of gramicidin A on bicelles and Eu3+-doped bicelles as studied by solid-state NMR and FT-IR spectroscopy Fulltext Access 13 Pages 2006
Combining precision spin-probe partitioning with time-resolved fluorescence quenching to study micelles: Application to micelles of pure lysomyristoylphosphatidylcholine (LMPC) and LMPC mixed with sodium dodecyl sulfate Fulltext Access 13 Pages 2006
Multi-component analysis of marine lipids in fish gonads with emphasis on phospholipids using high resolution NMR spectroscopy Fulltext Access 13 Pages 2006
NMR and HPLC-MS/MS analysis of synthetically prepared linoleic acid diol glucuronides Fulltext Access 13 Pages 2006
Effect of silicon level on rate, quality and progression of bone healing within silicate-substituted porous hydroxyapatite scaffolds Fulltext Access 13 Pages 2006
Poly (d,l-lactic acid) macroporous guidance scaffolds seeded with Schwann cells genetically modified to secrete a bi-functional neurotrophin implanted in the completely transected adult rat thoracic spinal cord Fulltext Access 13 Pages 2006
Temperature-responsive hydroxybutyl chitosan for the culture of mesenchymal stem cells and intervertebral disk cells Fulltext Access 13 Pages 2006
A new in vivo screening model for posterior spinal bone formation: Comparison of ten calcium phosphate ceramic material treatments Fulltext Access 13 Pages 2006
Longevity and the evolution of the mitochondrial DNA-coded proteins in mammals Fulltext Access 13 Pages 2006
Porous Ti6Al4V scaffold directly fabricating by rapid prototyping: Preparation and in vitro experiment Fulltext Access 13 Pages 2006
Effect of surface-adsorbed proteins and phosphorylation inhibitor AG18 on intracellular protein expression in adherent macrophages Fulltext Access 13 Pages 2006
Biomimetic modification of titanium dental implant model surfaces using the RGDSP-peptide sequence: A cell morphology study Fulltext Access 13 Pages 2006
The use of poly(ethylene glycol) hydrogels to investigate the impact of ECM chemistry and mechanics on smooth muscle cells Fulltext Access 13 Pages 2006
Finalizing the properties of porous scaffolds of aliphatic polyesters through radiation sterilization Fulltext Access 13 Pages 2006
Differential inflammatory macrophage response to rutile and titanium particles Fulltext Access 13 Pages 2006
In vivo behavior of calcium phosphate scaffolds with four different pore sizes Fulltext Access 13 Pages 2006
Cyclic flexure and laminar flow synergistically accelerate mesenchymal stem cell-mediated engineered tissue formation: Implications for engineered heart valve tissues Fulltext Access 13 Pages 2006
Tissue engineering-based cartilage repair with allogenous chondrocytes and gelatin–chondroitin–hyaluronan tri-copolymer scaffold: A porcine model assessed at 18, 24, and 36 weeks Fulltext Access 13 Pages 2006
The uptake of titanium ions by hydroxyapatite particles—structural changes and possible mechanisms Fulltext Access 13 Pages 2006
Phosphoproteomic profiling of human SH-SY5Y neuroblastoma cells during response to 6-hydroxydopamine-induced oxidative stress Fulltext Access 13 Pages 2006
Presenilins Form ER Ca2+ Leak Channels, a Function Disrupted by Familial Alzheimer's Disease-Linked Mutations Fulltext Access 13 Pages 2006
Transcription of bxd Noncoding RNAs Promoted by Trithorax Represses Ubx in cis by Transcriptional Interference Fulltext Access 13 Pages 2006
A Bir1-Sli15 Complex Connects Centromeres to Microtubules and Is Required to Sense Kinetochore Tension Fulltext Access 13 Pages 2006
TRPV1+ Sensory Neurons Control β Cell Stress and Islet Inflammation in Autoimmune Diabetes Fulltext Access 13 Pages 2006
Hsp90 Cochaperone Aha1 Downregulation Rescues Misfolding of CFTR in Cystic Fibrosis Fulltext Access 13 Pages 2006
Crystal Structure of the DsbB-DsbA Complex Reveals a Mechanism of Disulfide Bond Generation Fulltext Access 13 Pages 2006
The Highly Conserved LepA Is a Ribosomal Elongation Factor that Back-Translocates the Ribosome Fulltext Access 13 Pages 2006
Genome-wide High-Resolution Mapping and Functional Analysis of DNA Methylation in Arabidopsis Fulltext Access 13 Pages 2006
A Complexin/Synaptotagmin 1 Switch Controls Fast Synaptic Vesicle Exocytosis Fulltext Access 13 Pages 2006
S100A1-deficient male mice exhibit increased exploratory activity and reduced anxiety-related responses Fulltext Access 13 Pages 2006
New perspectives on the role of SERCA2's Ca2+ affinity in cardiac function Fulltext Access 13 Pages 2006
Uniqueness of the mechanism of protein import into the peroxisome matrix: Transport of folded, co-factor-bound and oligomeric proteins by shuttling receptors Fulltext Access 13 Pages 2006
Opposite effect of caveolin-1 in the metabolism of high-density and low-density lipoproteins Fulltext Access 13 Pages 2006
Coordinated intracellular translocation of phosphoinositide-specific phospholipase C-δ with the cell cycle Fulltext Access 13 Pages 2006
Phosphoinositide-specific phospholipase C (PI-PLC) β1 and nuclear lipid-dependent signaling Fulltext Access 13 Pages 2006
Molecular probes for sensing the cholesterol composition of subcellular organelle membranes Fulltext Access 13 Pages 2006
Genomic structure, alternative maturation and tissue expression of the human BBOX1 gene Fulltext Access 13 Pages 2006
Solvent-dependent structure of two tryptophan-rich antimicrobial peptides and their analogs studied by FTIR and CD spectroscopy Fulltext Access 13 Pages 2006
Detection of protein carbonyls in aging liver tissue: A fluorescence-based proteomic approach Fulltext Access 13 Pages 2006