QSAR analyses on ginkgolides and their analogues using CoMFA, CoMSIA, and HQSAR Fulltext Access 10 Pages 2005
The discovery and preparation of disubstituted novel amino-aryl-piperidine-based renin inhibitors Fulltext Access 10 Pages 2005
Synthesis, biological evaluation and molecular modelling studies on benzothiadiazine derivatives as PDE4 selective inhibitors Fulltext Access 10 Pages 2005
Synthesis and antiviral activity of novel acyclic nucleosides in the 5-alkynyl- and 6-alkylfuro[2,3-d]pyrimidine series Fulltext Access 10 Pages 2005
Antimycobacterial compounds. Optimization of the BM 212 structure, the lead compound for a new pyrrole derivative class Fulltext Access 10 Pages 2005
Design, synthesis and preliminary biological evaluation of zatebradine analogues as potential blockers of the hyperpolarization-activated current Fulltext Access 10 Pages 2005
QSTR with extended topochemical atom indices. Part 5: Modeling of the acute toxicity of phenylsulfonyl carboxylates to Vibrio fischeri using genetic function approximation Fulltext Access 10 Pages 2005
In vitro evaluation of the anti-estrogenic activity of hydroxyl substituted diphenylnaphthyl alkene ligands for the estrogen receptor Fulltext Access 10 Pages 2005
Optimization of a coagulation factor VIIa inhibitor found in factor Xa inhibitor library Fulltext Access 10 Pages 2005
Design, development and synthesis of mixed bioconjugates of piperic acid-glycine, curcumin-glycine/alanine and curcumin-glycine-piperic acid and their antibacterial and antifungal properties Fulltext Access 10 Pages 2005
Human telomerase inhibition and cytotoxicity of regioisomeric disubstituted amidoanthraquinones and aminoanthraquinones Fulltext Access 10 Pages 2005
Identification of the minimal glycopeptide core recognized by T cells in a model for rheumatoid arthritis Fulltext Access 10 Pages 2005
Facile synthesis of the heptasaccharide repeating unit of O-deacetylated GXM of C. neoformans serotype B Fulltext Access 10 Pages 2005
Cyclic sulfamide HIV-1 protease inhibitors, with sidechains spanning from P2/P2â² to P1/P1â² Fulltext Access 10 Pages 2005
Synthesis and structure-activity relationships of benzyloxyphenyl derivatives as a novel class of NCX inhibitors: effects on heart failure Fulltext Access 10 Pages 2005
Synthesis, biological evaluation, and molecular modeling of novel thioacridone derivatives related to the anticancer alkaloid acronycine Fulltext Access 10 Pages 2005
Gene selection from microarray data for cancer classification-a machine learning approach Fulltext Access 10 Pages 2005
A macroscopic kinetic model for DNA polymerase elongation and high-fidelity nucleotide selection Fulltext Access 10 Pages 2005
GAME: A simple and efficient whole genome alignment method using maximal exact match filtering Fulltext Access 10 Pages 2005
Parameter estimation in modulated, unbranched reaction chains within biochemical systems Fulltext Access 10 Pages 2005
Rheological characterisation of primary and binary interactive bioadhesive gels composed of cellulose derivatives designed as ophthalmic viscosurgical devices Fulltext Access 10 Pages 2005
Effect of functionalization of multilayered polyelectrolyte films on motoneuron growth Fulltext Access 10 Pages 2005
Synthesis of C-5-thioglycopyranosides and their sulfonium derivatives from 1-C-(2â²-oxoalkyl)-5-S-acetylglycofuranosides Fulltext Access 10 Pages 2005
Analysis of acidic carbohydrates as their quaternary ammonium or phosphonium salts by matrix-assisted laser desorption/ionization mass spectrometry Fulltext Access 10 Pages 2005
Arabinosyl and glucosyl residues as structural features of acetylated galactomannans from green and roasted coffee infusions Fulltext Access 10 Pages 2005
Crystal structure and solid state 13C NMR analysis of nitrophenyl 2,3,4,6-tetra-O-acetyl-β-d-gluco- and d-galactopyranosides Fulltext Access 10 Pages 2005
Determination of the three-dimensional structure of oligosaccharides in the solid state from experimental 13C NMR data and ab initio chemical shift surfaces Fulltext Access 10 Pages 2005
Structural analysis of carrageenans from the red alga, Callophyllis hombroniana Mont. Kütz (Kallymeniaceae, Rhodophyta) Fulltext Access 10 Pages 2005
Revised structures for the capsular polysaccharides from Staphylococcus aureus Types 5 and 8, components of novel glycoconjugate vaccines Fulltext Access 10 Pages 2005
Studies toward a conjugate vaccine for anthrax. Synthesis and characterization of anthrose [4,6-dideoxy-4-(3-hydroxy-3-methylbutanamido)-2-O-methyl-d-glucopyranose] and its methyl glycosides Fulltext Access 10 Pages 2005
Carbohydrate, glycolipid, and lipid components from the photobiont (Scytonema sp.) of the lichen, Dictyomema glabratum Fulltext Access 10 Pages 2005
Characteristics of degraded cellulose obtained from steam-exploded wheat straw Fulltext Access 10 Pages 2005
Structural analysis of the lipopolysaccharide of Pasteurella multocida strain VP161: identification of both Kdo-P and Kdo-Kdo species in the lipopolysaccharide Fulltext Access 10 Pages 2005
Synthesis of heptasaccharide and nonasaccharide analogues of the lentinan repeating unit Fulltext Access 10 Pages 2005
Synthesis and radioiodination of some daunorubicin and doxorubicin derivatives Fulltext Access 10 Pages 2005
Characterization of biodegradable drug delivery vehicles with the adhesive properties of leukocytes II: effect of degradation on targeting activity Fulltext Access 10 Pages 2005
High-performance size-exclusion chromatography (HPSEC) and fluorophore-assisted carbohydrate electrophoresis (FACE) to describe the chain-length distribution of debranched starch Fulltext Access 10 Pages 2005
Synthesis of glycosyl amino acids by light-induced coupling of photoreactive amino acids with glycosylamines and 1-C-aminomethyl glycosides Fulltext Access 10 Pages 2005
Isolation, characterization and structural determination of a unique type of arabinogalactan from an immunostimulatory extract of Chlorella pyrenoidosa Fulltext Access 10 Pages 2005
De- and rehydration behavior of α,α-trehalose dihydrate under humidity-controlled atmospheres Fulltext Access 10 Pages 2005
The chemical synthesis of 2-deoxy-2-fluorodisaccharide probes of the hen egg white lysozyme mechanism Fulltext Access 10 Pages 2005
Cytotoxic and antitumoral properties in a series of new, ring D modified, olivacine analogues Fulltext Access 10 Pages 2005
Berberine, a strong polyriboadenylic acid binding plant alkaloid: spectroscopic, viscometric, and thermodynamic study Fulltext Access 10 Pages 2005
Design, modelling, synthesis and biological evaluation of peptidomimetic phosphinates as inhibitors of matrix metalloproteinases MMP-2 and MMP-8 Fulltext Access 10 Pages 2005
Design, synthesis, and biological evaluation of N-acetyl-2-(or 3-)carboxymethylbenzenesulfonamides as cyclooxygenase isozyme inhibitors Fulltext Access 10 Pages 2005
A new structural alternative in benzo[b]furans for antimicrobial activity Fulltext Access 10 Pages 2005
Density-functional theory and ab initio Hartree–Fork studies on the structural parameters and chemical activity of the free radicals generated by benzoquinone and hydroquinone Fulltext Access 10 Pages 2005
Synthesis and antitumor evaluation of novel 5-substituted-4-hydroxy-8-nitroquinazolines as EGFR signaling-targeted inhibitors Fulltext Access 10 Pages 2005
Synthesis and antitrichinellosis activity of some 2-substituted-[1,3]thiazolo[3,2-a]benzimidazol-3(2H)-ones Fulltext Access 10 Pages 2005
Design, synthesis, and biological characterization of potential antiatherogenic nitric oxide releasing tocopherol analogs Fulltext Access 10 Pages 2005
Synthesis and evaluation of bifunctional nitrocatechol inhibitors of pig liver catechol-O-methyltransferase Fulltext Access 10 Pages 2005
A cyclic PNA-based compound targeting domain IV of HCV IRES RNA inhibits in vitro IRES-dependent translation Fulltext Access 10 Pages 2005
Synthetic multifunctional pores that open and close in response to chemical stimulation Fulltext Access 10 Pages 2005
Furoxan analogues of the histamine H3-receptor antagonist imoproxifan and related furazan derivatives Fulltext Access 10 Pages 2005
Design, synthesis, and biological evaluation of linear 1-(4-, 3- or 2-methylsulfonylphenyl)-2-phenylacetylenes: A novel class of cyclooxygenase-2 inhibitors Fulltext Access 10 Pages 2005
Homology modelling and active-site-mutagenesis study of the catalytic domain of the pneumococcal phosphorylcholine esterase Fulltext Access 10 Pages 2005
Structure–activity studies of uptake and phototoxicity with heavy-chalcogen analogues of tetramethylrosamine in vitro in chemosensitive and multidrug-resistant cells Fulltext Access 10 Pages 2005
9-Oxime-3-ketolides: Modification at the C-11,12-diol moiety and antibacterial activities against key respiratory pathogens Fulltext Access 10 Pages 2005
Antitumor activity and distribution of pyrroloiminoquinones in the sponge genus Zyzzya Fulltext Access 10 Pages 2005
Synthesis and cytotoxicity of epoxide and pyrazole analogs of the combretastatins Fulltext Access 10 Pages 2005
Synthesis of 5-haloethynyl- and 5-(1,2-dihalo)vinyluracil nucleosides: Antiviral activity and cellular toxicity Fulltext Access 10 Pages 2005
Preparation of highly substituted γ-lactam follicle stimulating hormone receptor agonists Fulltext Access 10 Pages 2005
An anionic inositol phosphate glycan pseudotetrasaccharide exhibits high insulin-mimetic activity in rat adipocytes Fulltext Access 10 Pages 2005
Optimized N-phenyl-N′-(2-chloroethyl)ureas as potential antineoplastic agents: Synthesis and growth inhibition activity Fulltext Access 10 Pages 2005
Aza-bicyclic amino acid carboxamides as α4β1/α4β7 integrin receptor antagonists Fulltext Access 10 Pages 2005
Structural characterization of the carbohydrate backbone of the lipooligosaccharide of the marine bacterium Arenibacter certesii strain KMM 3941T Fulltext Access 10 Pages 2005
Fixation of distal femoral osteotomies with self-reinforced polymer/bioactive glass rods: an experimental study on rabbits Fulltext Access 10 Pages 2005
Tethering poly(ethylene glycol)s to improve the surface biocompatibility of poly(acrylonitrile-co-maleic acid) asymmetric membranes Fulltext Access 10 Pages 2005
The effect of PEGT/PBT scaffold architecture on the composition of tissue engineered cartilage Fulltext Access 10 Pages 2005
Mesoscopic spatial designs of nano- and microfiber meshes for tissue-engineering matrix and scaffold based on newly devised multilayering and mixing electrospinning techniques Fulltext Access 10 Pages 2005
The effects of collagen fiber orientation on the flexural properties of pericardial heterograft biomaterials Fulltext Access 10 Pages 2005
Characterization of aqueous dispersions of Fe3O4 nanoparticles and their biomedical applications Fulltext Access 10 Pages 2005
Intracellular protein phosphorylation in adherent U937 monocytes mediated by various culture conditions and fibronectin-derived surface ligands Fulltext Access 10 Pages 2005
Effect of low oxygen concentrations on growth and α-amylase production of Aspergillus oryzae in model solid-state fermentation systems Fulltext Access 10 Pages 2005
Cloneless genomic DNA analysis: an efficient and simple methods for de novo genomic sequencing projects and gap filling Fulltext Access 10 Pages 2005
Degenerate oligonucleotide gene shuffling (DOGS) and random drift mutagenesis (RNDM): Two complementary techniques for enzyme evolution Fulltext Access 10 Pages 2005
Donepezil–tacrine hybrid related derivatives as new dual binding site inhibitors of AChE Fulltext Access 10 Pages 2005
Characterisation of Ca– and Al–pectate gels by thermal analysis and FT-IR spectroscopy Fulltext Access 10 Pages 2005
Action pattern of Valencia orange PME de-esterification of high methoxyl pectin and characterization of modified pectins Fulltext Access 10 Pages 2005
Galactans from cystocarpic plants of the red seaweed Callophyllis variegata (Kallymeniaceae, Gigartinales) Fulltext Access 10 Pages 2005
Structural modification of phenylpropanoid-derived compounds and the effects on their participation in redox processes Fulltext Access 10 Pages 2005
Design, synthesis, and biological evaluation of N-acetyl-2-carboxybenzenesulfonamides: a novel class of cyclooxygenase-2 (COX-2) inhibitors Fulltext Access 10 Pages 2005
Zidampidine, an aryl phosphate derivative of AZT: in vivo pharmacokinetics, metabolism, toxicity, and anti-viral efficacy against hemorrhagic fever caused by Lassa virus Fulltext Access 10 Pages 2005
Improved synthesis of daunomycin conjugates with triplex-forming oligonucleotides. The polypurine tract of HIV-1 as a target Fulltext Access 10 Pages 2005
Dual DNA recognition codes of a short peptide derived from the basic leucine zipper protein EmBP1 Fulltext Access 10 Pages 2005
Novel cytotoxic monotetrahydrofuranic Annonaceous acetogenins from Annona montana Fulltext Access 10 Pages 2005