Principles of covalent binding of reactive metabolites and examples of activation of bis-electrophiles by conjugation Fulltext Access 10 Pages 2005
Reduced effectiveness of HMR 1098 in blocking cardiac sarcolemmal KATP channels during metabolic stress Fulltext Access 10 Pages 2005
TGF-β1 induces cardiac hypertrophic responses via PKC-dependent ATF-2 activation Fulltext Access 10 Pages 2005
A calcium channel blocker amlodipine increases coronary blood flow via both adenosine- and NO-dependent mechanisms in ischemic hearts Fulltext Access 10 Pages 2005
A comparative serial echocardiographic analysis of cardiac structure and function in rats subjected to pressure or volume overload Fulltext Access 10 Pages 2005
Tachycardia increases NADPH oxidase activity and RyR2 S-glutathionylation in ventricular muscle Fulltext Access 10 Pages 2005
Isoproterenol does not enhance Ca-dependent Na/Ca exchange current in intact rabbit ventricular myocytes Fulltext Access 10 Pages 2005
Macrophage colony-stimulating factor expression in retrovirally transduced cells is dependent upon both the adherence status of the target cells and its 5â² flanking untranslated region Fulltext Access 10 Pages 2005
Competitive inhibition of the dengue virus NS3 serine protease by synthetic peptides representing polyprotein cleavage sites Fulltext Access 10 Pages 2005
The novel structure and chemistry of iron-sulfur clusters in the adenosylmethionine-dependent radical enzyme biotin synthase Fulltext Access 10 Pages 2005
The enzymology of cystathionine biosynthesis: strategies for the control of substrate and reaction specificity Fulltext Access 10 Pages 2005
Regulatory network of lipid-sensing nuclear receptors: roles for CAR, PXR, LXR, and FXR Fulltext Access 10 Pages 2005
Transgenic overexpression of SUR1 in the heart suppresses sarcolemmal KATP Fulltext Access 10 Pages 2005
Redox regulation of nerve growth factor-induced neuronal differentiation of PC12 cells through modulation of the nerve growth factor receptor, TrkA Fulltext Access 10 Pages 2005
BCL11A-dependent recruitment of SIRT1 to a promoter template in mammalian cells results in histone deacetylation and transcriptional repression Fulltext Access 10 Pages 2005
The Gly-Arg-rich C-terminal domain of pea nucleolin is a DNA helicase that catalytically translocates in the 5â²- to 3â²-direction Fulltext Access 10 Pages 2005
Purification, characterization cloning, and sequencing of metalloendopeptidase from Streptomyces septatus TH-2 Fulltext Access 10 Pages 2005
Ascorbate peroxidase, a scavenger of hydrogen peroxide in glyoxysomal membranes Fulltext Access 10 Pages 2005
Pyridinium cationic lipids in gene delivery: an in vitro and in vivo comparison of transfection efficiency versus a tetraalkylammonium congener Fulltext Access 10 Pages 2005
Interactions of mammalian cytochrome P450, NADPH-cytochrome P450 reductase, and cytochrome b5 enzymes Fulltext Access 10 Pages 2005
Inhibitory effect of conjugated eicosapentaenoic acid on human DNA topoisomerases I and II Fulltext Access 10 Pages 2005
A collection of bovine cDNA probes for gene expression profiling in muscle Fulltext Access 10 Pages 2005
DNA microarray-based detection and identification of Chlamydia and Chlamydophila spp. Fulltext Access 10 Pages 2005
Quantification of ALS1 gene expression in Candida albicans biofilms by RT-PCR using hybridisation probes on the LightCycler⢠Fulltext Access 10 Pages 2005
Angiotensin II increases phosphodiesterase 5A expression in vascular smooth muscle cells: A mechanism by which angiotensin II antagonizes cGMP signaling Fulltext Access 10 Pages 2005
Focus on Kir6.2: a key component of the ATP-sensitive potassium channel Fulltext Access 10 Pages 2005
Cyclooxygenase-2 promotes early atherosclerotic lesion formation in ApoE-deficient and C57BL/6 mice Fulltext Access 10 Pages 2005
Claudin-5 localizes to the lateral membranes of cardiomyocytes and is altered in utrophin/dystrophin-deficient cardiomyopathic mice Fulltext Access 10 Pages 2005
Rapid stimulation causes electrical remodeling in cultured atrial myocytes Fulltext Access 10 Pages 2005
Gαq-coupled receptors in human atrium function through protein kinase C ε and δ Fulltext Access 10 Pages 2005
Effects of menadione and its derivative on cultured cardiomyocytes with mitochondrial disorders Fulltext Access 10 Pages 2005
N-glycosylation influences the latency and catalytic properties of mammalian purple acid phosphatase Fulltext Access 10 Pages 2005
7-Ketocholesterol predisposes human aorta smooth muscle cells to Fas-mediated death Fulltext Access 10 Pages 2005
Resveratrol enhances neovascularization in the infarcted rat myocardium through the induction of thioredoxin-1, heme oxygenase-1 and vascular endothelial growth factor Fulltext Access 10 Pages 2005
Soluble factors released by endothelial progenitor cells promote migration of endothelial cells and cardiac resident progenitor cells Fulltext Access 10 Pages 2005
Interleukin-1β attenuates β-very low-density lipoprotein uptake and its receptor expression in vascular smooth muscle cells Fulltext Access 10 Pages 2005
Role of c-Jun NH2-terminal kinase in G-protein-coupled receptor agonist-induced cardiac plasminogen activator inhibitor-1 expression Fulltext Access 10 Pages 2005
SIH-a novel lipophilic iron chelator-protects H9c2 cardiomyoblasts from oxidative stress-induced mitochondrial injury and cell death Fulltext Access 10 Pages 2005
Differential functional effects of two 5-HT4 receptor isoforms in adult cardiomyocytes Fulltext Access 10 Pages 2005
Time-dependent changes in myocardial structure following discrete injury in mice deficient of matrix metalloproteinase-3 Fulltext Access 10 Pages 2005
Young MLP deficient mice show diastolic dysfunction before the onset of dilated cardiomyopathy Fulltext Access 10 Pages 2005
Site-directed mutagenesis and spectroscopic studies of the iron-binding site of (S)-2-hydroxypropylphosphonic acid epoxidase Fulltext Access 10 Pages 2005
Mangiferin, a natural occurring glucosyl xanthone, increases susceptibility of rat liver mitochondria to calcium-induced permeability transition Fulltext Access 10 Pages 2005
Apical uptake and transepithelial transport of sphingosine monomers through intact human intestinal epithelial cells: Physicochemical and molecular modeling studies Fulltext Access 10 Pages 2005
Intercalation into the DNA double helix and in vivo biological activity of water-soluble planar [Pt(diimine)(N,N-dihydroxyethyl-Nâ²-benzoylthioureato)]+Clâ complexes: A study of their thermal stability, their CD spectra and their gel mobility Fulltext Access 10 Pages 2005
Efficient expression, purification, and characterization of C-terminally tagged, recombinant human asparagine synthetase Fulltext Access 10 Pages 2005
Doxorubicin increases intracellular hydrogen peroxide in PC3 prostate cancer cells Fulltext Access 10 Pages 2005
Display of somatostatin-related peptides in the complementarity determining regions of an antibody light chain Fulltext Access 10 Pages 2005
Two enzymes, BtaA and BtaB, are sufficient for betaine lipid biosynthesis in bacteria Fulltext Access 10 Pages 2005
Characterization of thimet- and neurolysin-like activities in Escherichia coli M3A peptidases and description of a specific substrate Fulltext Access 10 Pages 2005
Enhanced fusion of myoblasts with myofibers for efficient gene delivery induced by a partially purified protein fraction from rat muscle extract Fulltext Access 10 Pages 2005
Properties of human and rabbit cytosolic serine hydroxymethyltransferase are changed by single nucleotide polymorphic mutations Fulltext Access 10 Pages 2005
Human intestinal and lung cell lines exposed to β-carotene show a large variation in intracellular levels of β-carotene and its metabolites Fulltext Access 10 Pages 2005
A novel homodimeric lectin from Astragalus mongholicus with antifungal activity Fulltext Access 10 Pages 2005
Kinetics and crystal structure of human purine nucleoside phosphorylase in complex with 7-methyl-6-thio-guanosine Fulltext Access 10 Pages 2005
Studies on the transglucosylation reactions of cassava and Thai rosewood β-glucosidases using 2-deoxy-2-fluoro-glycosyl-enzyme intermediates Fulltext Access 10 Pages 2005
Solute diffusivity correlates with mechanical properties and matrix density of compressed articular cartilage Fulltext Access 10 Pages 2005
Enzymatic characterization of human mitochondrial C1-tetrahydrofolate synthase Fulltext Access 10 Pages 2005
A possible restriction of ferro- and ferricyanide oxidoreductase activities of rat liver mitochondria by the outer membrane Fulltext Access 10 Pages 2005
Aminoethylation in model peptides reveals conditions for maximizing thiol specificity Fulltext Access 10 Pages 2005
Trp-262 is a key residue for the hydrolytic and transglucosidic reactivity of the Aspergillus niger family 3 β-glucosidase: Substitution results in enzymes with mainly transglucosidic activity Fulltext Access 10 Pages 2005
A region C-terminal to the proline-rich core of p47phox regulates activation of the phagocyte NADPH oxidase by interacting with the C-terminal SH3 domain of p67phox Fulltext Access 10 Pages 2005
Optimal control of coupled spin dynamics: design of NMR pulse sequences by gradient ascent algorithms Fulltext Access 10 Pages 2005
Backbone-only restraints for fast determination of the protein fold: The role of paramagnetism-based restraints. Cytochrome b562 as an example Fulltext Access 10 Pages 2005
Evaluation of spin trapping agents and trapping conditions for detection of cell-generated reactive oxygen species Fulltext Access 10 Pages 2005
Distinct but overlapping functions of Hsp70, Hsp90, and an Hsp70 nucleotide exchange factor during protein biogenesis in yeast Fulltext Access 10 Pages 2005
The N-terminal membrane anchor domain of the membrane-bound prostacyclin synthase involved in the substrate presentation of the coupling reaction with cyclooxygenase Fulltext Access 10 Pages 2005
A protective association between catalase and isocitrate lyase in peroxisomes Fulltext Access 10 Pages 2005
Measurement and characterization of C-3 epimerization activity toward vitamin D3 Fulltext Access 10 Pages 2005
On the difference in stability between horse and sperm whale myoglobins Fulltext Access 10 Pages 2005
Porin and cytochrome oxidase containing contact sites involved in the oxidation of cytosolic NADH Fulltext Access 10 Pages 2005
The influence of substrate on the spectral properties of oxyferrous wild-type and T252A cytochrome P450-CAM Fulltext Access 10 Pages 2005
Probing prime substrate binding sites of human dipeptidyl peptidase-IV using competitive substrate approach Fulltext Access 10 Pages 2005
The pro-sequence domain of streptopain directs the folding of the mature enzyme Fulltext Access 10 Pages 2005
Activation of sphingomyelinase from Bacillus cereus by Zn2+ hitherto accepted as a strong inhibitor Fulltext Access 10 Pages 2005
Overexpression of manganese superoxide dismutase protects against ATP depletion-mediated cell death of proximal tubule cells Fulltext Access 10 Pages 2005
Detection of intracellular lactate with localized diffusion {1H-13C}-spectroscopy in rat glioma in vivo Fulltext Access 10 Pages 2005
Identification of a novel zebrafish SULT1 cytosolic sulfotransferase: Cloning, expression, characterization, and developmental expression study Fulltext Access 10 Pages 2005
Analysis of the stability and function of nucleoplasmin through cysteine mutants Fulltext Access 10 Pages 2005
Purification and characterization of a novel ATP-independent type I DNA topoisomerase from a marine methylotroph Fulltext Access 10 Pages 2005
Supraphysiological concentrations of 5-aminolevulinic acid dimerize in solution to produce superoxide radical anions via a protonated dihydropyrazine intermediate Fulltext Access 10 Pages 2005
CYP35: Xenobiotically induced gene expression in the nematode Caenorhabditis elegans Fulltext Access 10 Pages 2005
Elevated cAMP level attenuates 2-deoxy-d-ribose-induced oxidative damage in pancreatic β-cells Fulltext Access 10 Pages 2005
Serine proteinase over-expression in relation to deltamethrin resistance in Culex pipiens pallens Fulltext Access 10 Pages 2005
Human CD69 associates with an N-terminal fragment of calreticulin at the cell surface Fulltext Access 10 Pages 2005
Purification, cloning, and functional expression of phenylalanine aminomutase: The first committed step in Taxol side-chain biosynthesis Fulltext Access 10 Pages 2005
1α,25-Dihydroxy-vitamin D3 in combination with 17β-estradiol lowers the cortical expression of heat shock protein-27 following experimentally induced focal cortical ischemia in rats Fulltext Access 10 Pages 2005