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Molecular Biology Research Articles

Substrate-trapping techniques in the identification of cellular PTP targets
Fulltext Access 10 Pages 2005
Quantitative measurements of NO reaction kinetics with a Clark-type electrode
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Effects of mechanistically distinct NF-κB inhibitors on glial inducible nitric-oxide synthase expression
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Nitrosative stress results in irreversible inhibition of purified mitochondrial complexes I and III without modification of cofactors
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Over-expression of human lysosomal α-mannosidase in mouse embryonic stem cells
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Mitochondrial voltage-dependent anion channel gene family in Drosophila melanogaster: Complex patterns of evolution, genomic organization, and developmental expression
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Downregulation of myelination, energy, and translational genes in Menkes disease brain
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Rapid, species-specific detection of uropathogen 16S rDNA and rRNA at ambient temperature by dot-blot hybridization and an electrochemical sensor array
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A homology model for human α-l-iduronidase: Insights into human disease
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White matter involvement in mitochondrial diseases
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The use of yeast mitochondria to study the properties of wild-type and mutant human mitochondrial ornithine transporter
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Methods for identifying extracellular ligands of RPTPs
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Yeast substrate-trapping system for isolating substrates of protein tyrosine phosphatases: Isolation of substrates for protein tyrosine phosphatase receptor type z
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TGF-β1 enhances degradation of IFN-γ-induced iNOS protein via proteasomes in RAW 264.7 cells
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Use of fluorescent sphingolipid analogs to study lipid transport along the endocytic pathway
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Development of experimental designs for atherosclerosis studies in mice
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Regulatory interfaces between the stress protein response and other gene expression programs in the cell
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SDR grafting-a new approach to antibody humanization
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Advanced electrochemical sensors for cell cancer monitoring
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Aptamers with fluorescence-signaling properties
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Gene discovery in neuropharmacological and behavioral studies using Affymetrix microarray data
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Use of minigene systems to dissect alternative splicing elements
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Fluorescence approaches for monitoring interactions of Rho GTPases with nucleotides, regulators, and effectors
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In vitro and in vivo assays to assess the functions of calnexin and calreticulin in ER protein folding and quality control
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Glycoprotein reglucosylation
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Optimization of BLyS production and purification from Escherichia coli
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Accumulation of ubiquitin-conjugated cytokeratin fragments in tumor cells
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Plasma free amino acid profile in cancer patients
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Dynamics of colorectal cancer
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Natural selection in neoplastic progression of Barrett's esophagus
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High-level heterologous expression and properties of a novel lipase from Ralstonia sp. M1
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Optimisation of insect cell growth in deep-well blocks: development of a high-throughput insect cell expression screen
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Tetracycline-regulated highly inducible expression of the human prion protein in murine 3T3 cells
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Development of an inducible protein expression system based on the protozoan host Leishmania tarentolae
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Open reading frame yjbI of Bacillus subtilis codes for truncated hemoglobin
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Overexpression and purification of recombinant human interferon alpha2b in Escherichia coli
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Characterization of 16 human G protein-coupled receptors expressed in baculovirus-infected insect cells
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PEGylated murine Granulocyte-macrophage colony-stimulating factor: Production, purification, and characterization
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Biochemical and pathological evaluation of long-lived mice with globoid cell leukodystrophy after bone marrow transplantation
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The propeptide is not required to produce catalytically active neutral protease from Bacillus stearothermophilus
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Characterization of a recombinant granzyme B derivative as a “restriction” protease
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Comparative evaluation of two purification methods of anti-CD19-c-myc-His6-Cys scFv
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Optimization of expression and purification of two biologically active chimeric fusion proteins that consist of human interleukin-13 and Pseudomonas exotoxin in Escherichia coli
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Bacterial expression and enzymatic activity analysis of ME1, a ribosome-inactivating protein from Mirabilis expansa
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Multidrug transporter MexB of Pseudomonas aeruginosa: overexpression, purification, and initial structural characterization
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Cloning and characterization of the rat HIF-1α prolyl-4-hydroxylase-1 gene
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Improving expression and solubility of rice proteins produced as fusion proteins in Escherichia coli
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Tight transcriptional regulation of foreign genes in insect cells using an ecdysone receptor-based inducible system
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Rate of transport of l-arginine is independent of the expression of inducible nitric oxide synthase in HEK 293 cells
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Super-induction of HO-1 in macrophages stimulated with lipopolysaccharide by prior depletion of glutathione decreases iNOS expression and NO production
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Cyclin-dependent kinase 11p58 interacts with HBO1 and enhances its histone acetyltransferase activity
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High frequency single-mode resonators for EPR spectroscopy enabling rotations of the sample about two orthogonal axes
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Structural anisotropy and internal magnetic fields in trabecular bone: Coupling solution and solid dipolar interactions
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An analytical methodology for magnetic field control in unilateral NMR
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Cumulative “roof effect” in high-resolution in vivo 31P NMR spectra of human calf muscle and the Clebsch-Gordan coefficients of ATP at 1.5 T
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Tendon xanthomas in familial hypercholesterolemia are associated with a differential inflammatory response of macrophages to oxidized LDL
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Sumoylation of the nucleocapsid protein of severe acute respiratory syndrome coronavirus
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Alternative signaling pathways: When, where and why?
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Proteolytic mechanisms in necrotic cell death and neurodegeneration
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Proteasome plasticity
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Arabidopsis thaliana MTP1 is a Zn transporter in the vacuolar membrane which mediates Zn detoxification and drives leaf Zn accumulation
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HER2 signaling downregulation by trastuzumab and suppression of the PI3K/Akt pathway: An unexpected effect on TRAIL-induced apoptosis
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Proteolytic cleavage of ALF into α- and β-subunits that form homologous and heterologous complexes with somatic TFIIA and TRF2 in male germ cells
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On-resonance low B1 pulses for imaging of the effects of PARACEST agents
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Tubulin cofactor A gene silencing in mammalian cells induces changes in microtubule cytoskeleton, cell cycle arrest and cell death
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RNA silencing in Drosophila
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Preventing transcriptional gene silencing by active DNA demethylation
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Pathways through the small RNA world of plants
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Transgenic mice expressing bovine PrP with a four extra repeat octapeptide insert mutation show a spontaneous, non-transmissible, neurodegenerative disease and an expedited course of BSE infection
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SNARE-mediated membrane traffic modulates RhoA-regulated focal adhesion formation
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Interactions of DC-SIGN with Mac-1 and CEACAM1 regulate contact between dendritic cells and neutrophils
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Optical biosensor provides insights for bradykinin B2 receptor signaling in A431 cells
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Eckol isolated from Ecklonia cava attenuates oxidative stress induced cell damage in lung fibroblast cells
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Roles for lysine residues of the MH2 domain of Smad3 in transforming growth factor-β signaling
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Polyomavirus EGFP-pseudocapsids: Analysis of model particles for introduction of proteins and peptides into mammalian cells
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Chronic depletion of glutathione (GSH) and minimal modification of LDL in vivo: its prevention by glutathione mono ester (GME) therapy
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Effect of optimal dietary therapy upon visual function in children with long-chain 3-hydroxyacyl CoA dehydrogenase and trifunctional protein deficiency
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The genetic basis of bone marrow failure syndromes in children
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Optic atrophies in metabolic disorders
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Genetic and genomic systems to study methylmalonic acidemia
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Potential structure/function relationships of predicted secondary structural elements of tau
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β-Carotene interaction with NNK in the AJ-mouse model: Effects on cell proliferation, tumor formation and retinoic acid responsive genes
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Towards a better understanding of carotenoid metabolism in animals
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Towards a model to explain the intragenic complementation in the heteromultimeric protein propionyl-CoA carboxylase
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The protective effect of α-crystallin against acute inflammation in mice
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Suppressive effects of dietary curcumin on the increased activity of renal ornithine decarboxylase in mice treated with a renal carcinogen, ferric nitrilotriacetate
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The effect of short-term kaempferol exposure on reactive oxygen levels and integrity of human (HL-60) leukaemic cells
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Cardiac volume overload rapidly induces oxidative stress-mediated myocyte apoptosis and hypertrophy
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Endotoxin recognition: In fish or not in fish?
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Cloning, characterization and DNA immunization of an Onchocerca volvulus glyceraldehyde-3-phosphate dehydrogenase (Ov-GAPDH)
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The hepatitis B virus X protein up-regulates lymphotoxin α expression in hepatocytes
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Inhibition of rat brain mitochondrial electron transport chain activity by dopamine oxidation products during extended in vitro incubation: Implications for Parkinson's disease
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HIV-1 interaction with human mannose receptor (hMR) induces production of matrix metalloproteinase 2 (MMP-2) through hMR-mediated intracellular signaling in astrocytes
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SIMQUADNMR: a program for simulation and interpretation of multiple quantum-filtered NMR spectra of quadrupolar nuclei
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Numerical simulation of PRESS localized MR spectroscopy
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Computing the B1 field of the toroidal MRI coil
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Homo-nuclear 13C J-decoupling in uniformly 13C-enriched solid proteins
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NMR spectroscopy in inhomogeneous B0 and B1 fields with non-linear correlation
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Magnetic resonance in systems with equivalent spin-1/2 nuclides. Part 1
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Planar microresonators for EPR experiments
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