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Daneshyari Molecular Medicine Journas Latest Articles

Molecular Medicine Research Articles

[186Re]Liposomal doxorubicin (Doxil): in vitro stability, pharmacokinetics, imaging and biodistribution in a head and neck squamous cell carcinoma xenograft model
Fulltext Access 10 Pages 2009
Food allergy/hypersensitivity: Antigenicity or timing?
Fulltext Access 10 Pages 2009
The remodeling of connexin in the hypertrophied right ventricular in pulmonary arterial hypertension and the effect of a dual ET receptor antagonist (bosentan)
Fulltext Access 10 Pages 2009
Histological expression of angiogenic factors: VEGF, PDGFRα, and HIF-1α in Hodgkin lymphoma
Fulltext Access 10 Pages 2009
The challenge of apocrine proliferations of the breast: A morphologic approach
Fulltext Access 10 Pages 2009
Biopsies of colorectal clinical polyps – emergence of diagnostic information on deeper levels
Fulltext Access 10 Pages 2009
Hepatocyte growth factor suppresses tumor cell apoptosis in nasopharyngeal carcinoma by upregulating Bcl-2 protein expression
Fulltext Access 10 Pages 2009
Expression of xenobiotic and steroid hormone metabolizing enzymes in hepatocellular tumors of the non-cirrhotic liver
Fulltext Access 10 Pages 2009
CD24 expression has a prognostic impact in breast carcinoma
Fulltext Access 10 Pages 2009
[18F]Fallypride dopamine D2 receptor studies using delayed microPET scans and a modified Logan plot
Fulltext Access 10 Pages 2009
Tumor targeting and SPECT imaging properties of an 111In-labeled galectin-3 binding peptide in prostate carcinoma
Fulltext Access 10 Pages 2009
18F-Labeled benzylideneaniline derivatives as new ligands for β-amyloid plaque imaging in Alzheimer's disease
Fulltext Access 10 Pages 2009
Vitamin C enters mouse T cells as dehydroascorbic acid in vitro and does not recapitulate in vivo vitamin C effects
Fulltext Access 10 Pages 2009
Cu(II) bis(thiosemicarbazone) radiopharmaceutical binding to serum albumin: further definition of species dependence and associated substituent effects
Fulltext Access 10 Pages 2009
Evaluation of an anti-p185HER2 (scFv-CH2-CH3)2 fragment following radioiodination using two different residualizing labels: SGMIB and IB-Mal-d-GEEEK
Fulltext Access 10 Pages 2009
Synthesis, radiolabeling, in vitro and in vivo evaluation of [18F]-FPECMO as a positron emission tomography radioligand for imaging the metabotropic glutamate receptor subtype 5
Fulltext Access 10 Pages 2009
Radiolabeled annexin V for imaging apoptosis in radiated human follicular thyroid carcinomas — is an individualized protocol necessary?
Fulltext Access 10 Pages 2009
Mono and bis-6-arylbenzimidazo[1,2-c]quinazolines: A new class of antimicrobial agents
Fulltext Access 10 Pages 2009
Total synthesis and anticancer activity of highly potent novel glycolipid derivatives
Fulltext Access 10 Pages 2009
Graphical contents list
Fulltext Access 10 Pages 2009
Conformationally constrained analogues of N′-(4-tert-butylbenzyl)-N-(4-methylsulfonylaminobenzyl)thiourea as TRPV1 antagonists
Fulltext Access 10 Pages 2009
Molecular modeling and inhibition of phospholipase A2 by polyhydroxy phenolic compounds
Fulltext Access 10 Pages 2009
Quantitative structure–activity relationship (QSAR) of aryl alkenyl amides/imines for bacterial efflux pump inhibitors
Fulltext Access 10 Pages 2009
Prediction of CCR5 receptor binding affinity of substituted 1-(3,3-diphenylpropyl)-piperidinyl amides and ureas based on the heuristic method, support vector machine and projection pursuit regression
Fulltext Access 10 Pages 2009
Ablation of Stat3 by siRNA Alters Gene Expression Profiles in JEG-3 Cells: A Systems Biology Approach
Fulltext Access 10 Pages 2009
Cutaneous distribution of plasmacytoid dendritic cells in lupus erythematosus. Selective tropism at the site of epithelial apoptotic damage
Fulltext Access 10 Pages 2009
Rheological and Physiological Consequences of Conversion of the Maternal Spiral Arteries for Uteroplacental Blood Flow during Human Pregnancy
Fulltext Access 10 Pages 2009
Fuel utilization by hypothalamic neurons: roles for ROS
Fulltext Access 10 Pages 2009
IGF-dependent and IGF-independent actions of IGF-binding protein-1 and -2: implications for metabolic homeostasis
Fulltext Access 10 Pages 2009
Leptin Acts via Leptin Receptor-Expressing Lateral Hypothalamic Neurons to Modulate the Mesolimbic Dopamine System and Suppress Feeding
Fulltext Access 10 Pages 2009
Ablation of Neutral Cholesterol Ester Hydrolase 1 Accelerates Atherosclerosis
Fulltext Access 10 Pages 2009
The Control of Food Intake: Behavioral versus Molecular Perspectives
Fulltext Access 10 Pages 2009
Differential Placental Gene Expression in Severe Preeclampsia
Fulltext Access 10 Pages 2009
Novel Soluble Flt-1 Isoforms in Plasma and Cultured Placental Explants from Normotensive Pregnant and Preeclamptic Women
Fulltext Access 10 Pages 2009
Altered Global Gene Expression in First Trimester Placentas of Women Destined to Develop Preeclampsia
Fulltext Access 10 Pages 2009
Differential Placental Hormone Gene Expression during Pregnancy in a Transgenic Mouse Containing the Human Growth Hormone/Chorionic Somatomammotropin Locus
Fulltext Access 10 Pages 2009
Regioselective synthesis of dispiro[1H-indene-2,3′-pyrrolidine-2′,3″-[3H]indole]-1,2″(1″H)-diones of potential anti-tumor properties
Fulltext Access 10 Pages 2009
The Isolation and Characterization of a Novel Telomerase Immortalized First Trimester Trophoblast Cell Line, Swan 71
Fulltext Access 10 Pages 2009
The proprotein convertase furin in human trophoblast: Possible role in promoting trophoblast cell migration and invasion
Fulltext Access 10 Pages 2009
Identification of critical antibody-binding sites in the HIV-1 gp41 six-helix bundle core as potential targets for HIV-1 fusion inhibitors
Fulltext Access 10 Pages 2009
The pharmacodynamic effect of sirolimus: Individual variation of cytokine mRNA expression profiles in human whole blood samples
Fulltext Access 10 Pages 2009
The variation in cytoplasmic distribution of mouse peritoneal macrophage during phagocytosis modulated by mangiferin, an immunomodulator
Fulltext Access 10 Pages 2009
Antitumor efficacy induced by human ovarian cancer cells secreting IL-21 alone or combination with GM-CSF cytokines in nude mice model
Fulltext Access 10 Pages 2009
Free intracellular Ca2+ regulates bacterial lipopolysaccharide induction of iNOS in human macrophages
Fulltext Access 10 Pages 2009
Microbicidal property of B1 cell derived mononuclear phagocyte
Fulltext Access 10 Pages 2009
Delayed recruitment of lymphocytes into the lungs of CD30-deficient mice during aerogenic Mycobacterium avium infections
Fulltext Access 10 Pages 2009
Zymosan treatment of mouse mast cells enhances dectin-1 expression and induces dectin-1-dependent reactive oxygen species (ROS) generation
Fulltext Access 10 Pages 2009
Synthesis and in vitro trichomonicidal, giardicidal and amebicidal activity of N-acetamide(sulfonamide)-2-methyl-4-nitro-1H-imidazoles
Fulltext Access 10 Pages 2009
Assessing the chemical diversity of an hsp90 database
Fulltext Access 10 Pages 2009
Cyclocondensation reaction of heterocyclic carbonyl compounds, Part XIII: Synthesis and cytotoxic activity of some 3,7-diaryl-5-(3,4,5-trimethoxyphenyl)pyrazolo[4,3-e][1,2,4]triazines
Fulltext Access 10 Pages 2009
Design, synthesis and pharmacological evaluation of new 1-[3-(4-arylpiperazin-1-yl)-2-hydroxy-propyl]-3,3-diphenylpyrrolidin-2-one derivatives with antiarrhythmic, antihypertensive, and α-adrenolytic activity
Fulltext Access 10 Pages 2009
Facile synthesis and in vitro properties of 1-alkyl- and 1-alkyl-N-propargyl-1,2,3,4-tetrahydroisoquinoline derivatives on PC12 cells
Fulltext Access 10 Pages 2009
Preparation and antitubercular activities in vitro and in vivo of novel Schiff bases of isoniazid
Fulltext Access 10 Pages 2009
S- and C-nucleosidoquinazoline as new nucleoside analogs with potential analgesic and anti-inflammatory activity
Fulltext Access 10 Pages 2009
Physicochemical properties and membrane interactions of anti-apoptotic derivatives 2-(4-fluorophenyl)-3-(pyridin-4-yl)imidazo[1,2-a]pyridine depending on the hydroxyalkylamino side chain length and conformation: An NMR and ESR study
Fulltext Access 10 Pages 2009
Discovering a new analogue of thalidomide which may be used as a potent modulator of TNF-α production
Fulltext Access 10 Pages 2009
Synthesis and anticonvulsant activity of new N-[(4-arylpiperazin-1-yl)-alkyl] derivatives of 3-phenyl-pyrrolidine-2,5-dione
Fulltext Access 10 Pages 2009
Synthesis of glycose carbamides and evaluation of the induction of erythroid differentiation of human erythroleukemic K562 cells
Fulltext Access 10 Pages 2009
Synthesis and in vitro anticancer activity of 2,4-azolidinedione-acetic acids derivatives
Fulltext Access 10 Pages 2009
Synthesis and antitumor activity of novel dithiocarbamate substituted chromones
Fulltext Access 10 Pages 2009
Discovery of a new family of bis-8-hydroxyquinoline substituted benzylamines with pro-apoptotic activity in cancer cells: Synthesis, structure–activity relationship, and action mechanism studies
Fulltext Access 10 Pages 2009
Comparative chemometric modeling of cytochrome 3A4 inhibitory activity of structurally diverse compounds using stepwise MLR, FA-MLR, PLS, GFA, G/PLS and ANN techniques
Fulltext Access 10 Pages 2009
Novel derivatives of 6-mercaptopurine: Synthesis, characterization and antiproliferative activities of S-allylthio-mercaptopurines
Fulltext Access 10 Pages 2009
Synthesis and anticancer activity of N-bis(trifluoromethyl)alkyl-N′-thiazolyl and N-bis(trifluoromethyl)alkyl-N′-benzothiazolyl ureas
Fulltext Access 10 Pages 2009
Design, cytotoxic and fluorescent properties of novel N-phosphorylalkyl substituted E,E-3,5-bis(arylidene)piperid-4-ones
Fulltext Access 10 Pages 2009
Synthesis, biological evaluation and molecular modeling of oxoisoaporphine and oxoaporphine derivatives as new dual inhibitors of acetylcholinesterase/butyrylcholinesterase
Fulltext Access 10 Pages 2009
Large ring 1,3-bridged 2-azetidinones: Experimental and theoretical studies
Fulltext Access 10 Pages 2009
Studies on chemical structure modification and biology of a natural product, Gambogic acid (I): Synthesis and biological evaluation of oxidized analogues of gambogic acid
Fulltext Access 10 Pages 2009
New acyclic nucleosides analogues as potential analgesic, anti-inflammatory, anti-oxidant and anti-microbial derived from pyrimido[4,5-b]quinolines
Fulltext Access 10 Pages 2009
Modeling the activity of furin inhibitors using artificial neural network
Fulltext Access 10 Pages 2009
Crystal structures, antioxidation and DNA binding properties of Dy(III) complexes with Schiff-base ligands derived from 8-hydroxyquinoline-2-carboxaldehyde and four aroylhydrazines
Fulltext Access 10 Pages 2009
Design, synthesis and biological evaluation of novel fluorinated docetaxel analogues
Fulltext Access 10 Pages 2009
Synthesis, biological evaluation and 2D-QSAR analysis of benzoxazoles as antimicrobial agents
Fulltext Access 10 Pages 2009
Application of desirability-based multi(bi)-objective optimization in the design of selective arylpiperazine derivates for the 5-HT1A serotonin receptor
Fulltext Access 10 Pages 2009
Synthesis, pharmacological and antiviral activity of 1,3-thiazepine derivatives
Fulltext Access 10 Pages 2009
Synthesis and in vitro antitumor activities of novel 4-anilinoquinazoline derivatives
Fulltext Access 10 Pages 2009
Synthesis, antiarrhythmic and anticoagulant activities of novel thiazolo derivatives from methyl 2-(thiazol-2-ylcarbamoyl)acetate
Fulltext Access 11 Pages 2009
Design, synthesis and evaluation of novel uracil acetamide derivatives as potential inhibitors of Plasmodium falciparum dUTP nucleotidohydrolase
Fulltext Access 11 Pages 2009
Synthesis of 2-styrylchromones as a novel class of antiproliferative agents targeting carcinoma cells
Fulltext Access 11 Pages 2009
Discovery of novel acetanilide derivatives as potent and selective β3-adrenergic receptor agonists
Fulltext Access 11 Pages 2009
Synthesis and characterization of dinuclear macrocyclic cobalt(II), copper(II) and zinc(II) complexes derived from 2,2,2′,2′-S,S[bis(bis-N,N-2-thiobenzimidazolyloxalato-1,2-ethane)]: DNA binding and cleavage studies
Fulltext Access 11 Pages 2009
Phenethyl pyridines with non-polar internal substitutents as selective ligands for estrogen receptor beta
Fulltext Access 11 Pages 2009
Primaquine dipeptide derivatives bearing an imidazolidin-4-one moiety at the N-terminus as potential antimalarial prodrugs
Fulltext Access 11 Pages 2009
Synthesis and evaluation of some novel isochroman carboxylic acid derivatives as potential anti-diabetic agents
Fulltext Access 11 Pages 2009
Design, synthesis and AChE inhibitory activity of indanone and aurone derivatives
Fulltext Access 11 Pages 2009
Fragment and knowledge-based design of selective GSK-3β inhibitors using virtual screening models
Fulltext Access 11 Pages 2009
Synthesis and activity of fibrillogenesis peptide inhibitors related to the 17–21 β-amyloid sequence
Fulltext Access 11 Pages 2009
Substituted quinolinyl chalcones and quinolinyl pyrimidines as a new class of anti-infective agents
Fulltext Access 11 Pages 2009
Hansch analysis of substituted benzoic acid benzylidene/furan-2-yl-methylene hydrazides as antimicrobial agents
Fulltext Access 11 Pages 2009
Synthesis, HIV-RT inhibitory activity and SAR of 1-benzyl-1H-1,2,3-triazole derivatives of carbohydrates
Fulltext Access 11 Pages 2009
Tetrahydronaphthyl azole oxime ethers: The conformationally rigid analogues of oxiconazole as antibacterials
Fulltext Access 11 Pages 2009
Anti-trypanosomatid benzofuroxans and deoxygenated analogues: Synthesis using polymer-supported triphenylphosphine, biological evaluation and mechanism of action studies
Fulltext Access 11 Pages 2009
New derivatives of 3,5-substituted-1,4,2-dioxazoles: Synthesis and activity against Entamoeba histolytica
Fulltext Access 11 Pages 2009
Design and in silico screening of combinatorial library of antimalarial analogs of triclosan inhibiting Plasmodium falciparum enoyl-acyl carrier protein reductase
Fulltext Access 11 Pages 2009
Synthesis and evaluation of pyrido[1,2-a]pyrimidines as inhibitors of nitric oxide synthases
Fulltext Access 11 Pages 2009
Synthesis and evaluation of a novel series of heterocyclic oleanolic acid derivatives with anti-osteoclast formation activity
Fulltext Access 11 Pages 2009
Novel CYP17 inhibitors: Synthesis, biological evaluation, structure–activity relationships and modelling of methoxy- and hydroxy-substituted methyleneimidazolyl biphenyls
Fulltext Access 11 Pages 2009
Identification of putative steroid-binding sites in human ABCB1 and ABCG2
Fulltext Access 11 Pages 2009
Synthesis and antibacterial activity of novel 15-membered macrolide derivatives: 4″-Carbamate, 11,12-cyclic carbonate-4″-carbamate and 11,4″-di-O-arylcarbamoyl analogs of azithromycin
Fulltext Access 11 Pages 2009
Novel modified steroid derivatives of androstanolone as chemotherapeutic anti-cancer agents
Fulltext Access 11 Pages 2009
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