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Daneshyari Molecular Medicine Journas Latest Articles

Molecular Medicine Research Articles

Neurotransmitter responsiveness during early maturation of neural progenitor cells
Fulltext Access 11 Pages 2009
Role of the sub-cellular localization of RasGAP fragment N2 for its ability to sensitize cancer cells to genotoxin-induced apoptosis
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Changes of higher order chromatin arrangements during major genome activation in bovine preimplantation embryos
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Tamoxifen inhibits tumor cell invasion and metastasis in mouse melanoma through suppression of PKC/MEK/ERK and PKC/PI3K/Akt pathways
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Both cell-surface and secreted CSF-1 expressed by tumor cells metastatic to bone can contribute to osteoclast activation
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The renal cell carcinoma-associated oncogenic fusion protein PRCCTFE3 provokes p21WAF1/CIP1-mediated cell cycle delay
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Hsp27 associates with the titin filament system in heat-shocked zebrafish cardiomyocytes
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Skp2 enhances polyubiquitination and degradation of TIS21/BTG2/PC3, tumor suppressor protein, at the downstream of FoxM1
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Abnormal differentiation, hyperplasia and embryonic/perinatal lethality in BK5-T/t transgenic mice
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Differences in goblet cell differentiation between Crohn's disease and ulcerative colitis
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Active DNA demethylation and DNA repair
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Suppression of chondrogenesis by Id helix–loop–helix proteins in murine embryonic orofacial tissue
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Reduced serum concentration is permissive for increased in vitro endocrine differentiation from murine embryonic stem cells
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δ-Opioid receptor-stimulated Akt signaling in neuroblastoma × glioma (NG108-15) hybrid cells involves receptor tyrosine kinase-mediated PI3K activation
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Axial differentiation and early gastrulation stages of the pig embryo
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Transcriptional control of the tumor- and hypoxia-marker carbonic anhydrase 9: A one transcription factor (HIF-1) show?
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Histone Deacetylase Inhibition Elicits an Evolutionarily Conserved Self-Renewal Program in Embryonic Stem Cells
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Small Molecules Efficiently Direct Endodermal Differentiation of Mouse and Human Embryonic Stem Cells
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Synergy between CD26/DPP-IV Inhibition and G-CSF Improves Cardiac Function after Acute Myocardial Infarction
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Differential Mobilization of Subsets of Progenitor Cells from the Bone Marrow
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An Efficient and Reversible Transposable System for Gene Delivery and Lineage-Specific Differentiation in Human Embryonic Stem Cells
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mTOR Mediates Wnt-Induced Epidermal Stem Cell Exhaustion and Aging
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Hedgehog Signaling Is Dispensable for Adult Hematopoietic Stem Cell Function
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Liver X Receptors and Oxysterols Promote Ventral Midbrain Neurogenesis In Vivo and in Human Embryonic Stem Cells
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Human Placenta Is a Potent Hematopoietic Niche Containing Hematopoietic Stem and Progenitor Cells throughout Development
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Activation and inactivation of the iron hormone hepcidin: Biochemical characterization of prohepcidin cleavage and sequential degradation to N-terminally truncated hepcidin isoforms
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Lacking of Aiolos accelerates pre-mature B cell apoptosis mediated by BCR signaling through elevation in cytochrome c release
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Regulation of the formation and trafficking of vesicles from Golgi by PCH family proteins during chemotaxis
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A systems biology view of cancer
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Inflammatory protein sPLA2-IIA abrogates TNFα-induced apoptosis in human astroglioma cells: Crucial role of ERK
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A systems biology approach to Down syndrome: Identification of Notch/Wnt dysregulation in a model of stem cells aging
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p38MAPK: stress responses from molecular mechanisms to therapeutics
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The role of bone-marrow-derived cells in tumor growth, metastasis initiation and progression
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Zinc transporters and cancer: a potential role for ZIP7 as a hub for tyrosine kinase activation
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p53 and the regulation of hepatocyte apoptosis: implications for disease pathogenesis
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Bronchopulmonary dysplasia and emphysema: in search of common therapeutic targets
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Whole-genome association studies of sporadic amyotrophic lateral sclerosis: are retroelements involved?
Fulltext Access 11 Pages 2009
Late-acquired incomplete stent apposition: morphologic characterization
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Autocrine TGF-β Signaling Maintains Tumorigenicity of Glioma-Initiating Cells through Sry-Related HMG-Box Factors
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TFE3 transcription factor regulates the expression of MAFB during macrophage differentiation
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Coxsackie adenovirus receptor (CAR) regulates integrin function through activation of p44/42 MAPK
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The role of meiotic cohesin REC8 in chromosome segregation in γ irradiation-induced endopolyploid tumour cells
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KCa2.3 channel-dependent hyperpolarization increases melanoma cell motility
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Eps15 interacts with ubiquitinated Cx43 and mediates its internalization
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Interference RNA (RNAi)-based silencing of endogenous thrombopoietin receptor (Mpl) in Dami cells resulted in decreased hNUDC-mediated megakaryocyte proliferation and differentiation
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BS69 undergoes SUMO modification and plays an inhibitory role in muscle and neuronal differentiation
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Necdin and TrkA contribute to modulation by p75NTR of resistance to oxidant stress
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Vascular endothelial growth factor promotes cardiac stem cell migration via the PI3K/Akt pathway
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Cdx2 and the Brm-type SWI/SNF complex cooperatively regulate villin expression in gastrointestinal cells
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CD148/DEP-1 association with areas of cytoskeletal organisation in macrophages
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Synthesis of 3,6-disubstituted 7H-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazines as novel analgesic/anti-inflammatory compounds
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Autophagy: Principles and significance in health and disease
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Lipid induced overexpression of NF-κB in skeletal muscle cells is linked to insulin resistance
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Gene expression of synaptosomal-associated protein 25 (SNAP-25) in the prefrontal cortex of the spontaneously hypertensive rat (SHR)
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TGF-β and fibrosis in different organs — molecular pathway imprints
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A critical evaluation of current staging of α-synuclein pathology in Lewy body disorders
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Scientific rationale for the development of gene therapy strategies for Parkinson's disease
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Loss of Kupffer cells in diet-induced obesity is associated with increased hepatic steatosis, STAT3 signaling, and further decreases in insulin signaling
Fulltext Access 11 Pages 2009
Synthesis and antibacterial activity of novel 5-(4-methyl-1H-1,2,3-triazole) methyl oxazolidinones
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A set of new amino acid descriptors applied in prediction of MHC class I binding peptides
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Docking, 3D-QSAR studies and in silico ADME prediction on c-Src tyrosine kinase inhibitors
Fulltext Access 11 Pages 2009
Synthesis and antimicrobial activities of novel quinoline derivatives carrying 1,2,4-triazole moiety
Fulltext Access 11 Pages 2009
Synthesis, characterization, DNA binding properties and antioxidant activity of Ln(III) complexes with hesperetin-4-one-(benzoyl) hydrazone
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High levels of thioredoxin reductase 1 modulate drug-specific cytotoxic efficacy
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Synthesis, crystal structures and antibacterial activity studies of aza-derivatives of phytoalexin from cotton plant – gossypol
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A label free quantitative proteomic analysis of the Saccharomyces cerevisiae nucleus
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Unravelling the nuclear matrix proteome
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The integral membrane of lysosomes: Its proteins and their roles in disease
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Biochemical and proteomic approaches for the study of membrane microdomains
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Proteomic approach for identification of protein S-nitrosation in mouse gastric mucosa treated with S-nitrosoglutathione
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Glycopeptide profiling of beta-2-glycoprotein I by mass spectrometry reveals attenuated sialylation in patients with antiphospholipid syndrome
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Optimization of protein solubilization for the analysis of the CD14 human monocyte membrane proteome using LC-MS/MS
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Proteomics of Arabidopsis redox proteins in response to methyl jasmonate
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Clinical collection and protein properties of expressed prostatic secretions as a source for biomarkers of prostatic disease
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Changes of defense proteins in the extracellular proteome of grapevine (Vitis vinifera cv. Gamay) cell cultures in response to elicitors
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Withaferin A sensitizes TRAIL-induced apoptosis through reactive oxygen species-mediated up-regulation of death receptor 5 and down-regulation of c-FLIP
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Mesenchymal Stem Cell Homing: The Devil Is in the Details
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Secreted Frizzled-Related Protein 1 Extrinsically Regulates Cycling Activity and Maintenance of Hematopoietic Stem Cells
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Thrombospondin-1–CD47 blockade and exogenous nitrite enhance ischemic tissue survival, blood flow and angiogenesis via coupled NO–cGMP pathway activation
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Interactions of oxysterols with membranes and proteins
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Anthrax toxins: A weapon to systematically dismantle the host immune defenses
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Bacillus anthracis physiology and genetics
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Taurine prevents cardiomyocyte death by inhibiting NADPH oxidase-mediated calpain activation
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Nrf2-regulated glutathione recycling independent of biosynthesis is critical for cell survival during oxidative stress
Fulltext Access 11 Pages 2009
GYY4137, a novel hydrogen sulfide-releasing molecule, protects against endotoxic shock in the rat
Fulltext Access 11 Pages 2009
Singlet-oxygen-mediated amino acid and protein oxidation: Formation of tryptophan peroxides and decomposition products
Fulltext Access 11 Pages 2009
Ethanol and tobacco smoke increase hepatic steatosis and hypoxia in the hypercholesterolemic apoE−/− mouse: Implications for a “multihit” hypothesis of fatty liver disease
Fulltext Access 11 Pages 2009
γ-Glutamyltransferase-dependent resistance to arsenic trioxide in melanoma cells and cellular sensitization by ascorbic acid
Fulltext Access 11 Pages 2009
Comparative proteomics analysis of caspase-9-protein complexes in untreated and cytochrome c/dATP stimulated lysates of NSCLC cells
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Radioprotective effects of manganese-containing superoxide dismutase mimics on ataxia–telangiectasia cells
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Chemistry and Reaction Mechanisms
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Neuroscience
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Receptor activator of nuclear factor-κB ligand-induced mouse osteoclast differentiation is associated with switching between NADPH oxidase homologues
Fulltext Access 11 Pages 2009
Correlation of F4-neuroprostanes levels in cerebrospinal fluid with outcome of aneurysmal subarachnoid hemorrhage in humans
Fulltext Access 11 Pages 2009
Sod2 knockdown in the musculature has whole-organism consequences in Drosophila
Fulltext Access 11 Pages 2009
Cardiotoxicity of calmidazolium chloride is attributed to calcium aggravation, oxidative and nitrosative stress, and apoptosis
Fulltext Access 11 Pages 2009
Efficacy of sauchinone as a novel AMPK-activating lignan for preventing iron-induced oxidative stress and liver injury
Fulltext Access 11 Pages 2009
JNK-dependent NFATc1 pathway positively regulates IL-13 gene expression induced by (–)-epigallocatechin-3-gallate in human basophilic KU812 cells
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Are antioxidants useful for treating skeletal muscle atrophy?
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Differential distribution of 4-hydroxynonenal adducts to sulfur and nitrogen residues in blood proteins as revealed using Raney nickel and gas chromatography–mass spectrometry
Fulltext Access 11 Pages 2009
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