Crystal Structure of Thermus thermophilus Δ1-Pyrroline-5-carboxylate Dehydrogenase Fulltext Access 12 Pages 2006
Using Evolutionary Information and Ancestral Sequences to Understand the Sequence–Function Relationship in GLP-1 Agonists Fulltext Access 12 Pages 2006
Structures of Human N-Acetylglucosamine Kinase in Two Complexes with N-Acetylglucosamine and with ADP/Glucose: Insights into Substrate Specificity and Regulation Fulltext Access 12 Pages 2006
The β4-β8 Groove Is an ATP-interactive Site in the α Crystallin Core Domain of the Small Heat Shock Protein, Human αB Crystallin Fulltext Access 12 Pages 2006
Mapping of the Auto-inhibitory Interactions of Protein Kinase R by Nuclear Magnetic Resonance Fulltext Access 12 Pages 2006
Formation, Characterization and Partial Purification of a Tn5 Strand Transfer Complex Fulltext Access 12 Pages 2006
Biological Units and their Effect upon the Properties and Prediction of Protein–Protein Interactions Fulltext Access 12 Pages 2006
Fibrillogenic and Non-fibrillogenic Ensembles of SDS-bound Human α-Synuclein Fulltext Access 12 Pages 2006
Crystal Structure of LAAO from Calloselasma rhodostoma with an l-Phenylalanine Substrate: Insights into Structure and Mechanism Fulltext Access 12 Pages 2006
Early Events in the Binding of the pPS10 Replication Protein RepA to Single Iteron and Operator DNA Sequences Fulltext Access 12 Pages 2006
Increased Chromatin Association of Sp1 in Interphase Cells by PP2A-mediated Dephosphorylations Fulltext Access 12 Pages 2006
The Role of Arg165 Towards Base Flipping, Base Stabilization and Catalysis in M.HhaI Fulltext Access 12 Pages 2006
Variations in the Unstructured C-terminal Tail of Interferons Contribute to Differential Receptor Binding and Biological Activity Fulltext Access 12 Pages 2006
The Closed Structure of an Archaeal DNA Ligase from Pyrococcus furiosus Fulltext Access 12 Pages 2006
Structural Basis for Detoxification and Oxidative Stress Protection in Membranes Fulltext Access 12 Pages 2006
The DICE-binding Activity of KH Domain 3 of hnRNP K Is Affected by c-Src-mediated Tyrosine Phosphorylation Fulltext Access 12 Pages 2006
SV40 Large T Antigen Up-regulates the Retrotransposition Frequency of Viral-like 30 Elements Fulltext Access 12 Pages 2006
Distinct Kinetic Mechanisms of the Two Classes of Aminoacyl-tRNA Synthetases Fulltext Access 12 Pages 2006
CeBRC-2 Stimulates D-loop Formation by RAD-51 and Promotes DNA Single-strand Annealing Fulltext Access 12 Pages 2006
Crystal Structure of d-Psicose 3-epimerase from Agrobacterium tumefaciens and its Complex with True Substrate d-Fructose: A Pivotal Role of Metal in Catalysis, an Active Site for the Non-phosphorylated Substrate, and its Conformational Changes Fulltext Access 12 Pages 2006
Structure of the Blm10–20 S Proteasome Complex by Cryo-electron Microscopy. Insights into the Mechanism of Activation of Mature Yeast Proteasomes Fulltext Access 12 Pages 2006
The Crystal Structure of a Thermophilic Glucose Binding Protein Reveals Adaptations that Interconvert Mono and Di-saccharide Binding Sites Fulltext Access 12 Pages 2006
Characterisation of the Conformational Properties of Urea-unfolded Im7: Implications for the Early Stages of Protein Folding Fulltext Access 12 Pages 2006
A Conserved Dimer and Global Conformational Changes in the Structure of apo-PknE Ser/Thr Protein Kinase from Mycobacterium tuberculosis Fulltext Access 12 Pages 2006
The Crystal Structure of Cdc42 in Complex with Collybistin II, a Gephyrin-interacting Guanine Nucleotide Exchange Factor Fulltext Access 12 Pages 2006
Role of E. coli NusA in Phage HK022 Nun-mediated Transcription Termination Fulltext Access 12 Pages 2006
Structural Basis of Substrate Specificity in Human Glyoxylate Reductase/Hydroxypyruvate Reductase Fulltext Access 12 Pages 2006
Self-association of the Transmembrane Domain of an Anthrax Toxin Receptor Fulltext Access 12 Pages 2006
The Third 20 Amino Acid Repeat Is the Tightest Binding Site of APC for β-Catenin Fulltext Access 12 Pages 2006
Molecular Dynamics Simulations of the Tetracycline-repressor Protein: The Mechanism of Induction Fulltext Access 12 Pages 2006
Domain Organization and Crystal Structure of the Catalytic Domain of E. coli RluF, a Pseudouridine Synthase that Acts on 23S rRNA Fulltext Access 12 Pages 2006
Calcium-dependent Tetramer Formation of S100A8 and S100A9 is Essential for Biological Activity Fulltext Access 12 Pages 2006
Structural Basis for Substrate Recognition by the Editing Domain of Isoleucyl-tRNA Synthetase Fulltext Access 12 Pages 2006
Structure and Substrate Recognition of the Escherichia coli DNA Adenine Methyltransferase Fulltext Access 12 Pages 2006
The X-ray Structure of the N-terminal Domain of PILB from Neisseria meningitidis Reveals a Thioredoxin-fold Fulltext Access 12 Pages 2006
ATP Synthase b Subunit Dimerization Domain: A Right-Handed Coiled Coil with Offset Helices Fulltext Access 12 Pages 2006
A Novel Mechanism of Interaction between α-Synuclein and Biological Membranes Fulltext Access 12 Pages 2006
Crystal Structure of Nicotinic Acid Mononucleotide Adenylyltransferase from Staphyloccocus aureus: Structural Basis for NaAD Interaction in Functional Dimer Fulltext Access 12 Pages 2006
Crystal Structure of 3-Chlorocatechol 1,2-dioxygenase Key Enzyme of a New Modified Ortho-pathway from the Gram-positive Rhodococcus opacus 1CP Grown on 2-chlorophenol Fulltext Access 12 Pages 2006
1.25 Å Resolution Crystal Structures of Human Haemoglobin in the Oxy, Deoxy and Carbonmonoxy Forms Fulltext Access 12 Pages 2006
Protein Refolding in Silico with Atom-based Statistical Potentials and Conformational Search Using a Simple Genetic Algorithm Fulltext Access 12 Pages 2006
Controlling Quaternary Structure Assembly: Subunit Interface Engineering and Crystal Structure of Dual Chain Avidin Fulltext Access 12 Pages 2006
Structural Basis for Molecular Recognition in an Affibody:Affibody Complex Fulltext Access 12 Pages 2006
The Structure of the Exopolyphosphatase (PPX) from Escherichia coli O157:H7 Suggests a Binding Mode for Long Polyphosphate Chains Fulltext Access 12 Pages 2006
Structural Characterization of Set1 RNA Recognition Motifs and their Role in Histone H3 Lysine 4 Methylation Fulltext Access 12 Pages 2006
Three-dimensional Structure of Iminodisuccinate Epimerase Defines the Fold of the MmgE/PrpD Protein Family Fulltext Access 12 Pages 2006
Crystal Structure of the Human Retinitis Pigmentosa 2 Protein and Its Interaction with Arl3 Fulltext Access 12 Pages 2006
Effects of covalently attached chondroitin sulfate on aggrecan cleavage by ADAMTS-4 and MMP-13 Fulltext Access 12 Pages 2006
The N-terminal 70-kDa fragment of fibronectin binds to cell surface fibronectin assembly sites in the absence of intact fibronectin Fulltext Access 12 Pages 2006
De Novo Tubular Nanostructure Design Based on Self-Assembly of β-Helical Protein Motifs Fulltext Access 12 Pages 2006
Flexible Fitting in 3D-EM Guided by the Structural Variability of Protein Superfamilies Fulltext Access 12 Pages 2006
Molecular Mechanism for the Regulation of Rho-Kinase by Dimerization and Its Inhibition by Fasudil Fulltext Access 12 Pages 2006
Solution Structure of the SWIRM Domain of Human Histone Demethylase LSD1 Fulltext Access 12 Pages 2006
Conformational Diversity in the TPR Domain-Mediated Interaction of Protein Phosphatase 5 with Hsp90 Fulltext Access 12 Pages 2006
The Structure of a Ketoreductase Determines the Organization of the β-Carbon Processing Enzymes of Modular Polyketide Synthases Fulltext Access 12 Pages 2006
The Structure of I-CeuI Homing Endonuclease: Evolving Asymmetric DNA Recognition from a Symmetric Protein Scaffold Fulltext Access 12 Pages 2006
Assessing Computational Amino Acid β-Turn Propensities with a Phage-Displayed Combinatorial Library and Directed Evolution Fulltext Access 12 Pages 2006
An Expanded Conformation of Single-Ring GroEL-GroES Complex Encapsulates an 86 kDa Substrate Fulltext Access 12 Pages 2006
Structure and Interactions at the Viral Surface of the Envelope Protein E1 of Semliki Forest Virus Fulltext Access 12 Pages 2006
Both direct and collagen-mediated signals are required for active vitamin D3-elicited differentiation of human osteoblastic cells: Roles of osterix, an osteoblast-related transcription factor Fulltext Access 12 Pages 2006
A Versatile Conformational Switch Regulates Reactivity in Human Branched-Chain α-Ketoacid Dehydrogenase Fulltext Access 12 Pages 2006
Complete Reaction Cycle of a Cocaine Catalytic Antibody at Atomic Resolution Fulltext Access 12 Pages 2006
The Crystal Structure of the Rare-Cutting Restriction Enzyme SdaI Reveals Unexpected Domain Architecture Fulltext Access 12 Pages 2006
Crystal Structure of Ethylbenzene Dehydrogenase from Aromatoleum aromaticum Fulltext Access 12 Pages 2006
Lengsin Is a Survivor of an Ancient Family of Class I Glutamine Synthetases Re-engineered by Evolution for a Role in the Vertebrate Lens Fulltext Access 12 Pages 2006
A Nitric Oxide Signaling Pathway Controls CREB-Mediated Gene Expression in Neurons Fulltext Access 12 Pages 2006
Crystal Structure of a Cbf5-Nop10-Gar1 Complex and Implications in RNA-Guided Pseudouridylation and Dyskeratosis Congenita Fulltext Access 12 Pages 2006
Opening Closed Arms: Long-Distance Activation of SMC ATPase by Hinge-DNA Interactions Fulltext Access 12 Pages 2006
The Control Mechanism for Lagging Strand Polymerase Recycling during Bacteriophage T4 DNA Replication Fulltext Access 12 Pages 2006
Structure of the Escherichia coli Heptosyltransferase WaaC: Binary Complexes with ADP AND ADP-2-deoxy-2-fluoro Heptose Fulltext Access 12 Pages 2006
The Crystal Structure of the Bacteriophage PSA Endolysin Reveals a Unique Fold Responsible for Specific Recognition of Listeria Cell Walls Fulltext Access 12 Pages 2006
Small-Angle X-ray Scattering Reveals the Solution Structure of a Bacteriophytochrome in the Catalytically Active Pr State Fulltext Access 12 Pages 2006
Serpin1 of Arabidopsis thaliana is a Suicide Inhibitor for Metacaspase 9 Fulltext Access 12 Pages 2006
Minimalist Protein Model as a Diagnostic Tool for Misfolding and Aggregation Fulltext Access 12 Pages 2006
High Resolution Structure of BipD: An Invasion Protein Associated with the Type III Secretion System of Burkholderia Pseudomallei Fulltext Access 12 Pages 2006
Sites of Interaction of a Precursor Polypeptide on the Export Chaperone SecB Mapped by Site-directed Spin Labeling Fulltext Access 12 Pages 2006
Functional and Structural Role of Amino Acid Residues in the Even-numbered Transmembrane α-Helices of the Bovine Mitochondrial Oxoglutarate Carrier Fulltext Access 12 Pages 2006
Changes in Nucleoporin Domain Topology in Response to Chemical Effectors Fulltext Access 12 Pages 2006
Identification and Characterization of the Nuclear Localization/Retention Signal in the EWS Proto-oncoprotein Fulltext Access 12 Pages 2006
Conformational Transition between Four and Five-stranded Phenylalanine Zippers Determined by a Local Packing Interaction Fulltext Access 12 Pages 2006
Shuffling of Discrete tRNASer Regions Reveals Differently Utilized Identity Elements in Yeast and Methanogenic Archaea Fulltext Access 12 Pages 2006
Bacteriophage T4 Capsid: A Unique Platform for Efficient Surface Assembly of Macromolecular Complexes Fulltext Access 12 Pages 2006
Subcellular Localization of Interacting Proteins by Bimolecular Fluorescence Complementation in Planta Fulltext Access 12 Pages 2006
Cofacial Heme Binding is Linked to Dimerization by a Bacterial Heme Transport Protein Fulltext Access 12 Pages 2006
Heteronuclear NMR Identifies a Nascent Helix in Intrinsically Disordered Dynein Intermediate Chain: Implications for Folding and Dimerization Fulltext Access 12 Pages 2006
The Energetic Network of Hotspot Residues between Cdc25B Phosphatase and its Protein Substrate Fulltext Access 12 Pages 2006
Dystrophin Dp71f Associates with the β1-Integrin Adhesion Complex to Modulate PC12 Cell Adhesion Fulltext Access 12 Pages 2006
A New Structural Domain in the Escherichia coli RcsC Hybrid Sensor Kinase Connects Histidine Kinase and Phosphoreceiver Domains Fulltext Access 12 Pages 2006
Sequence Identity of the Direct Repeats, DR1 and DR2, Contributes to the Discrimination between Primer Translocation and in Situ Priming During Replication of the Duck Hepatitis B Virus Fulltext Access 12 Pages 2006
The 1.7 Å Crystal Structure of Dronpa: A Photoswitchable Green Fluorescent Protein Fulltext Access 12 Pages 2006
One Protein, Two Enzymes Revisited: A Structural Entropy Switch Interconverts the Two Isoforms of Acireductone Dioxygenase Fulltext Access 12 Pages 2006
Tandem Sp1/Sp3 sites together with an Ets-1 site cooperate to mediate α11 integrin chain expression in mesenchymal cells Fulltext Access 12 Pages 2006
Differential cell adhesion to vocal fold extracellular matrix constituents Fulltext Access 12 Pages 2006