Lessons from functional analysis of AChE covalent and noncovalent inhibitors for design of AD therapeutic agents Fulltext Access 8 Pages 2005
Salicylic acid-induced inactivation of creatine kinase in the presence of lactoperoxidase and H2O2 Fulltext Access 8 Pages 2005
Mutagenic specificity of 2-acetylaminonaphthalene-derived DNA adduct in mammalian cells Fulltext Access 8 Pages 2005
Ozone-induced paradoxical sleep decrease is related to diminished acetylcholine levels in the medial preoptic area in rats Fulltext Access 8 Pages 2005
Biochemical evaluation of the inflammatory changes in cardiac, hepatic and renal tissues of adriamycin-administered rats and the modulatory role of exogenous heparin-derivative treatment Fulltext Access 8 Pages 2005
Effect of inducers of DT-diaphorase on the haemolytic activity and nephrotoxicity of 2-amino-1,4-naphthoquinone in rats Fulltext Access 8 Pages 2005
Subchronic toxic effects of tributyltin (TBT) and inorganic lead (PbII) in rats Fulltext Access 8 Pages 2005
Comparison of gene expression methods to identify genes responsive to perfluorooctane sulfonic acid Fulltext Access 8 Pages 2005
Oral administration of pyridostigmine bromide and huperzine A protects human whole blood cholinesterases from ex vivo exposure to soman Fulltext Access 8 Pages 2005
A peptide derived from acetylcholinesterase is a pivotal signalling molecule in neurodegeneration Fulltext Access 8 Pages 2005
The role of AChE active site gorge in determining stereoselectivity of charged and noncharged VX enantiomers Fulltext Access 8 Pages 2005
Transcriptional regulation of acetylcholinesterase-associated collagen ColQ in fast- and slow-twitch muscle fibers Fulltext Access 8 Pages 2005
Acetylcholinesterase (AChE) gene modification in transgenic animals: Functional consequences of selected exon and regulatory region deletion Fulltext Access 8 Pages 2005
Delivery of human acetylcholinesterase by adeno-associated virus to the acetylcholinesterase knockout mouse Fulltext Access 8 Pages 2005
Intestinal glutathione: determinant of mucosal peroxide transport, metabolism, and oxidative susceptibility Fulltext Access 9 Pages 2005
Genetic contributions to the risk assessment of microcystin in the environment Fulltext Access 9 Pages 2005
Stimulation of topoisomerase II-mediated DNA cleavage by benzene metabolites Fulltext Access 9 Pages 2005
Inorganic arsenite alters macrophage generation from human peripheral blood monocytes Fulltext Access 9 Pages 2005
Functional requirements for the optimal catalytic configuration of the AChE active center Fulltext Access 9 Pages 2005
Exposure to benzene and non-Hodgkin lymphoma, an epidemiologic overview and an ongoing case-control study in Shanghai Fulltext Access 9 Pages 2005
Molecular basis of interactions of cholinesterases with tight binding inhibitors Fulltext Access 9 Pages 2005
The metabolism of nonane, a JP-8 jet fuel component, by human liver microsomes, P450 isoforms and alcohol dehydrogenase and inhibition of human P450 isoforms by JP-8 Fulltext Access 9 Pages 2005
Interactions between the peripheral site and the acylation site in acetylcholinesterase Fulltext Access 9 Pages 2005
Shortened telomeres in murine scid cells expressing mutant hRAD54 coincide with reduction in recombination at telomeres Fulltext Access 9 Pages 2005
The use of genetically engineered mouse models of prostate cancer for nutrition and cancer chemoprevention research Fulltext Access 9 Pages 2005
Transcription-coupled repair: Impact on UV-induced mutagenesis in cultured rodent cells and mouse skin tumors Fulltext Access 9 Pages 2005
Transcription past DNA adducts derived from polycyclic aromatic hydrocarbons Fulltext Access 9 Pages 2005
Effects of estradiol and progesterone on the variability of the micronucleus assay Fulltext Access 9 Pages 2005
γ-Radiation-induced follicular degeneration in the prepubertal mouse ovary Fulltext Access 9 Pages 2005
5-Fluorouracil forward mutation assay in Salmonella: Determination of mutational target and spontaneous mutational spectra Fulltext Access 9 Pages 2005
Studying the synergistic damage effects induced by 1.8Â GHz radiofrequency field radiation (RFR) with four chemical mutagens on human lymphocyte DNA using comet assay in vitro Fulltext Access 9 Pages 2005
Roles of the polymerase and BRCT domains of Rev1 protein in translesion DNA synthesis in yeast in vivo Fulltext Access 9 Pages 2005
NAD(P)H oxidase/nitric oxide interactions in peroxisome proliferator activated receptor (PPAR)α-mediated cardiovascular effects Fulltext Access 9 Pages 2005
The impact of plasma folate levels of mothers and newborns on intrauterine growth retardation and birth weight Fulltext Access 9 Pages 2005
The use of biomarkers in surveillance, medical screening, and intervention Fulltext Access 9 Pages 2005
Design issues in cross-sectional biomarkers studies: Urinary biomarkers of PAH exposure and oxidative stress Fulltext Access 9 Pages 2005
Pleural malignant mesothelioma, genetic susceptibility and asbestos exposure Fulltext Access 9 Pages 2005
Cytochrome P450 enzyme-mediated degradation of Echinacea alkylamides in human liver microsomes Fulltext Access 9 Pages 2005
Significance and role of early-lesions in experimental colorectal carcinogenesis Fulltext Access 9 Pages 2005
Protective and detrimental effects of kaempferol in rat H4IIE cells: Implication of oxidative stress and apoptosis Fulltext Access 9 Pages 2005
Broccoli and watercress suppress matrix metalloproteinase-9 activity and invasiveness of human MDA-MB-231 breast cancer cells Fulltext Access 9 Pages 2005
Organic extract of diesel exhaust particles stimulates expression of Ia and costimulatory molecules associated with antigen presentation in rat peripheral blood monocytes but not in alveolar macrophages Fulltext Access 9 Pages 2005
2,3,7,8-Tetrachlorodibenzo-p-dioxin-induced change in intestinal function and pathology: evidence for the involvement of arylhydrocarbon receptor-mediated alteration of glucose transportation Fulltext Access 9 Pages 2005
Manifestation of arsenicosis patients and factors determining the duration of arsenic symptoms in Bangladesh Fulltext Access 9 Pages 2005
Air pollution particles activate NF-κB on contact with airway epithelial cell surfaces Fulltext Access 9 Pages 2005
Rat epidermal keratinocyte organotypic culture (ROC) as a model for chemically induced skin irritation testing Fulltext Access 9 Pages 2005
Derivation of a chemical-specific adjustment factor (CSAF) for use in the assessment of risk from chronic exposure to ethylene glycol: Application of international programme for chemical safety guidelines Fulltext Access 9 Pages 2005
Arsenite decreases CYP3A23 induction in cultured rat hepatocytes by transcriptional and translational mechanisms Fulltext Access 9 Pages 2005
“Fluorescent Cell Chip” for immunotoxicity testing: Development of the c-fos expression reporter cell lines Fulltext Access 9 Pages 2005
Toxicological implications of polymorphisms in receptors for xenobiotic chemicals: The case of the aryl hydrocarbon receptor Fulltext Access 9 Pages 2005
Inter-individual susceptibility to environmental toxicants-A current assessment Fulltext Access 9 Pages 2005
What determines the acceptability of genetically modified food that can improve human nutrition? Fulltext Access 9 Pages 2005
Does mechanistic understanding help in risk assessment-the example of dioxins Fulltext Access 9 Pages 2005
Time-dependent effect of p-Aminophenol (PAP) toxicity in renal slices and development of oxidative stress Fulltext Access 9 Pages 2005
Macrophages are involved in hexachlorobenzene-induced adverse immune effects Fulltext Access 9 Pages 2005
Arsenite enhances tumor necrosis factor-α-induced expression of vascular cell adhesion molecule-1 Fulltext Access 9 Pages 2005
The natural toxin juglone causes degradation of p53 and induces rapid H2AX phosphorylation and cell death in human fibroblasts Fulltext Access 9 Pages 2005
Plant lectins as carriers for oral drugs: Is wheat germ agglutinin a suitable candidate? Fulltext Access 9 Pages 2005
Specific dose-dependent damage of Lieberkühn crypts promoted by large doses of type 2 ribosome-inactivating protein nigrin b intravenous injection to mice Fulltext Access 9 Pages 2005
Inorganic mercury dissociates preassembled Fas/CD95 receptor oligomers in T lymphocytes Fulltext Access 9 Pages 2005
Implications of oxidative stress and hepatic cytokine (TNF-α and IL-6) response in the pathogenesis of hepatic collagenesis in chronic arsenic toxicity Fulltext Access 9 Pages 2005
Induction of hepatic and renal metallothionein synthesis by ferric nitrilotriacetate in mice: the role of MT as an antioxidant Fulltext Access 9 Pages 2005
Biomarkers in assessing residential insecticide exposures during pregnancy and effects on fetal growth Fulltext Access 9 Pages 2005
Biomarkers of exposure, effect, and susceptibility of arsenic-induced health hazards in Taiwan Fulltext Access 9 Pages 2005
Urinary porphyrins as biomarkers for arsenic exposure among susceptible populations in Guizhou province, China Fulltext Access 9 Pages 2005
Dead or dying: the importance of time in cytotoxicity assays using arsenite as an example Fulltext Access 9 Pages 2005
Protection from spontaneous hepatocellular damage by N-benzyl-d-glucamine dithiocarbamate in Long-Evans Cinnamon rats, an animal model of Wilson's disease Fulltext Access 9 Pages 2005
Inhibition of aromatase activity by methyl sulfonyl PCB metabolites in primary culture of human mammary fibroblasts Fulltext Access 9 Pages 2005
Increase in a distinct pulmonary macrophage subset possessing an antigen-presenting cell phenotype and in vitro APC activity following silica exposure Fulltext Access 9 Pages 2005
Inhibition of leukocyte function and interleukin-2 gene expression by 2-methylarachidonyl-(2â²-fluoroethyl)amide, a stable congener of the endogenous cannabinoid receptor ligand anandamide Fulltext Access 9 Pages 2005
Different cellular responses evoked by natural and stoichiometric synthetic chrysotile asbestos Fulltext Access 9 Pages 2005
Activation of ERK mitogen-activated protein kinase in human cells by the mycotoxin patulin Fulltext Access 9 Pages 2005
Protection of rats against 3-butene-1,2-diol-induced hepatotoxicity and hypoglycemia by N-acetyl-l-cysteine Fulltext Access 9 Pages 2005
Elastolytic activity and alveolar epithelial type-1 cell damage after chronic LPS inhalation: Effects of dexamethasone and rolipram Fulltext Access 9 Pages 2005
Green tea polyphenol epigallocatechin-3-gallate differentially modulates oxidative stress in PC12 cell compartments Fulltext Access 9 Pages 2005
Differential toxicity of sulfur mustard administered through percutaneous, subcutaneous, and oral routes Fulltext Access 9 Pages 2005
Contribution of acetaminophen-cysteine to acetaminophen nephrotoxicity in CD-1 mice: I. Enhancement of acetaminophen nephrotoxicity by acetaminophen-cysteine Fulltext Access 9 Pages 2005
MRP-1 expression levels determine strain-specific susceptibility to sodium arsenic-induced renal injury between C57BL/6 and BALB/c mice Fulltext Access 9 Pages 2005
Cytokine gene expression and activation of NF-κB in aniline-induced splenic toxicity Fulltext Access 9 Pages 2005
Developmental consequences of in utero sodium arsenate exposure in mice with folate transport deficiencies Fulltext Access 9 Pages 2005
Estrogenic and antiandrogenic activities of 17 benzophenone derivatives used as UV stabilizers and sunscreens Fulltext Access 9 Pages 2005
Cytogenetic damage in lymphocytes of patients undergoing therapy for small cell lung cancer and ovarian carcinoma Fulltext Access 9 Pages 2005