Three-dimensional Crystal Structure and Enzymic Characterization of β-Mannanase Man5A from Blue Mussel Mytilus edulis Fulltext Access 11 Pages 2006
Factors influencing the protective efficacy of a BCG homologous prime-boost vaccination regime against tuberculosis Fulltext Access 11 Pages 2006
Introducing point and deletion mutations into the P/C gene of human parainfluenza virus type 1 (HPIV1) by reverse genetics generates attenuated and efficacious vaccine candidates Fulltext Access 11 Pages 2006
Encapsulation of proteins and peptides into biodegradable poly(d,l-lactide-co-glycolide) microspheres prolongs and enhances antigen presentation by human dendritic cells Fulltext Access 11 Pages 2006
Non PC liposome entrapped promastigote antigens elicit parasite specific CD8+ and CD4+ T-cell immune response and protect hamsters against visceral leishmaniasis Fulltext Access 11 Pages 2006
Mouse model of respiratory Chlamydia pneumoniae infection for a genomic screen of subunit vaccine candidates Fulltext Access 11 Pages 2006
DNA vaccines co-expressing GP5 and M proteins of porcine reproductive and respiratory syndrome virus (PRRSV) display enhanced immunogenicity Fulltext Access 11 Pages 2006
Immunization with fibrillar Aβ1–42 in young and aged canines: Antibody generation and characteristics, and effects on CSF and brain Aβ Fulltext Access 11 Pages 2006
The Crystal Structure of a Plant 3-Ketoacyl-CoA Thiolase Reveals the Potential for Redox Control of Peroxisomal Fatty Acid β-Oxidation Fulltext Access 11 Pages 2006
Structure and Reaction Mechanism of l-Rhamnulose Kinase from Escherichia coli Fulltext Access 11 Pages 2006
New Roles for Key Residues in Helices H1 and H2 of the Escherichia coli H-NS N-terminal Domain: H-NS Dimer Stabilization and Hha Binding Fulltext Access 11 Pages 2006
Nudged Elastic Band Calculation of Minimal Energy Paths for the Conformational Change of a GG Non-canonical Pair Fulltext Access 11 Pages 2006
Solution Structure and Backbone Dynamics of the Trypanosoma cruzi Cysteine Protease Inhibitor Chagasin Fulltext Access 11 Pages 2006
Antibody response to influenza vaccination in the elderly: A quantitative review Fulltext Access 11 Pages 2006
Crystal Structure of Neoculin: Insights into its Sweetness and Taste-modifying Activity Fulltext Access 11 Pages 2006
Structural Insights of the Specificity and Catalysis of a Viral Histone H3 Lysine 27 Methyltransferase Fulltext Access 11 Pages 2006
Microsecond Dynamics of Protein–DNA Interactions: Direct Observation of the Wrapping/Unwrapping Kinetics of Single-stranded DNA around the E. coli SSB Tetramer Fulltext Access 11 Pages 2006
Probing the Structural Basis for the Difference in Thermostability Displayed by Family 10 Xylanases Fulltext Access 11 Pages 2006
A Large Domain Swap in the VirB11 ATPase of Brucella suis Leaves the Hexameric Assembly Intact Fulltext Access 11 Pages 2006
Membrane-transferring Sequences of the HIV-1 Gp41 Ectodomain Assemble into an Immunogenic Complex Fulltext Access 11 Pages 2006
Seeding-dependent Propagation and Maturation of β2-Microglobulin Amyloid Fibrils Under High Pressure Fulltext Access 11 Pages 2006
Common Motifs and Topological Effects in the Protein Folding Transition State Fulltext Access 11 Pages 2006
Sterol Regulatory Element-binding Protein-2 Negatively Regulates Low Density Lipoprotein Receptor-related Protein Transcription Fulltext Access 11 Pages 2006
Inhibition of HIV-1 replication by a peptide dimerization inhibitor of HIV-1 protease Fulltext Access 11 Pages 2006
Effectiveness of 2009 pandemic influenza A(H1N1) vaccines: A systematic review and meta-analysis Fulltext Access 11 Pages 2006
Identification and analysis of fitness of resistance mutations against the HCV protease inhibitor SCH 503034 Fulltext Access 11 Pages 2006
Combination chemotherapy, a potential strategy for reducing the emergence of drug-resistant influenza A variants Fulltext Access 11 Pages 2006
Enhancement of the infectivity of SARS-CoV in BALB/c mice by IMP dehydrogenase inhibitors, including ribavirin Fulltext Access 11 Pages 2006
Increasing prevalence of HIV-1 protease inhibitor-associated mutations correlates with long-term non-suppressive protease inhibitor treatment Fulltext Access 11 Pages 2006
Inhibition of respiratory syncytial virus in cultured cells by nucleocapsid gene targeted deoxyribozyme (DNAzyme) Fulltext Access 11 Pages 2006
Identification of inhibitors to papillomavirus type 16 E6 protein based on three-dimensional structures of interacting proteins Fulltext Access 11 Pages 2006
Application of the cycloSal-prodrug approach for improving the biological potential of phosphorylated biomolecules Fulltext Access 11 Pages 2006
Potent inhibition of HIV-1 gene expression and TAT-mediated apoptosis in human T cells by novel mono- and multitarget anti-TAT/Rev/Env ribozymes and a general purpose RNA-cleaving DNA-enzyme Fulltext Access 11 Pages 2006
The 2.1 Å Crystal Structure of copGFP, a Representative Member of the Copepod Clade Within the Green Fluorescent Protein Superfamily Fulltext Access 11 Pages 2006
Understanding the accessory viral proteins unique to the severe acute respiratory syndrome (SARS) coronavirus Fulltext Access 11 Pages 2006
Phylogenetic analysis of ORF5 and ORF7 sequences of porcine reproductive and respiratory syndrome virus (PRRSV) from PRRS-positive Italian farms: A showcase for PRRSV epidemiology and its consequences on farm management Fulltext Access 11 Pages 2006
Limited BVDV transmission and full protection against CSFV transmission in pigs experimentally infected with BVDV type 1b Fulltext Access 11 Pages 2006
Molecular characterization of bovine rotavirus circulating in beef and dairy herds in Argentina during a 10-year period (1994–2003) Fulltext Access 11 Pages 2006
Evaluation of Erysipelothrix rhusiopathiae vaccines in pigs by intradermal challenge and immune responses Fulltext Access 11 Pages 2006
Identification and immunological characterization of conserved Mycoplasma hyopneumoniae lipoproteins Mhp378 and Mhp651 Fulltext Access 11 Pages 2006
Evaluation of LSSP-PCR for identification of Leptospira spp. in urine samples of cattle with clinical suspicion of leptospirosis Fulltext Access 11 Pages 2006
Evaluation of hemagglutinin subtype 1 swine influenza viruses from the United States Fulltext Access 11 Pages 2006
Identification of T-helper and linear B epitope in the hypervariable region of nucleocapsid protein of PPRV and its use in the development of specific antibodies to detect viral antigen Fulltext Access 11 Pages 2006
Chapter 30: HPV vaccines and screening in the prevention of cervical cancer; conclusions from a 2006 workshop of international experts Fulltext Access 11 Pages 2006
Immunization with recombinant modified vaccinia Ankara (rMVA) constructs encoding the HA or NP gene protects ponies from equine influenza virus challenge Fulltext Access 11 Pages 2006
From Monomeric to Homodimeric Endonucleases and Back: Engineering Novel Specificity of LAGLIDADG Enzymes Fulltext Access 11 Pages 2006
Structure-based Stability Engineering of the Mouse IgG1 Fab Fragment by Modifying Constant Domains Fulltext Access 11 Pages 2006
Chimeric Fc Receptors Identify Ligand Binding Regions in Human Glycoprotein VI Fulltext Access 11 Pages 2006
Identification of Two Interaction Sites in SecY that Are Important for the Functional Interaction with SecA Fulltext Access 11 Pages 2006
Chain Length-dependent Binding of Fatty Acid Anions to Human Serum Albumin Studied by Site-directed Mutagenesis Fulltext Access 11 Pages 2006
A Novel Haem-binding Interface in the 22 kDa Haem-binding Protein p22HBP Fulltext Access 11 Pages 2006
Crucial Steps in the Structure Determination of the Na+/H+ Antiporter NhaA in its Native Conformation Fulltext Access 11 Pages 2006
Crystal Structure of a Multi-domain Immunophilin from Arabidopsis thaliana: A Paradigm for Regulation of Plant ABC Transporters Fulltext Access 11 Pages 2006
Thermus thermophilus Bacteriophage ϕYS40 Genome and Proteomic Characterization of Virions Fulltext Access 11 Pages 2006
The Crystal Structure of Mouse Nup35 Reveals Atypical RNP Motifs and Novel Homodimerization of the RRM Domain Fulltext Access 11 Pages 2006
Structural Differences in Aβ Amyloid Protofibrils and Fibrils Mapped by Hydrogen Exchange – Mass Spectrometry with On-line Proteolytic Fragmentation Fulltext Access 11 Pages 2006
Structural Basis for Phosphotyrosine Recognition by the Src Homology-2 Domains of the Adapter Proteins SH2-B and APS Fulltext Access 11 Pages 2006
Structure of the Bet3–Tpc6B Core of TRAPP: Two Tpc6 Paralogs Form Trimeric Complexes with Bet3 and Mum2 Fulltext Access 11 Pages 2006
Expression of Connexin47 in Oligodendrocytes is Regulated by the Sox10 Transcription Factor Fulltext Access 11 Pages 2006
Osmolyte Trimethylamine N-Oxide Converts Recombinant α-Helical Prion Protein to its Soluble β-Structured Form at High Temperature Fulltext Access 11 Pages 2006
The Crystal Structure of an ADP Complex of Bacillus subtilis Pyridoxal Kinase Provides Evidence for the Parallel Emergence of Enzyme Activity During Evolution Fulltext Access 11 Pages 2006
Point Mutations in Protein Globular Domains: Contributions from Function, Stability and Misfolding Fulltext Access 11 Pages 2006
Structural and Functional Studies of EpsC, a Crucial Component of the Type 2 Secretion System from Vibrio cholerae Fulltext Access 11 Pages 2006
Two Parts of the T3S4 Domain of the Hook-length Control Protein FliK Are Essential for the Substrate Specificity Switching of the Flagellar Type III Export Apparatus Fulltext Access 11 Pages 2006
Localization of Prefoldin Interaction Sites in the Hyperthermophilic Group II Chaperonin and Correlations between Binding Rate and Protein Transfer Rate Fulltext Access 11 Pages 2006
Direct Observation of Oligomeric Species formed in the Early Stages of Amyloid Fibril Formation using Electrospray Ionisation Mass Spectrometry Fulltext Access 11 Pages 2006
The Mitomycin C (MMC)-binding Protein from MMC-producing Microorganisms Protects from the Lethal Effect of Bleomycin: Crystallographic Analysis to Elucidate the Binding Mode of the Antibiotic to the Protein Fulltext Access 11 Pages 2006
Crystal Structures of BchU, a Methyltransferase Involved in Bacteriochlorophyll c Biosynthesis, and its Complex with S-adenosylhomocysteine: Implications for Reaction Mechanism Fulltext Access 11 Pages 2006
Recognition and Positioning of mRNA in the Ribosome by tRNAs with Expanded Anticodons Fulltext Access 11 Pages 2006
Asp302 Determines Potassium Dependence of a RadA Recombinase from Methanococcus voltae Fulltext Access 11 Pages 2006
The Crystal Structure of the Transthyretin-like Protein from Salmonella dublin, a Prokaryote 5-Hydroxyisourate Hydrolase Fulltext Access 11 Pages 2006
Extended Substrate Recognition in Caspase-3 Revealed by High Resolution X-ray Structure Analysis Fulltext Access 11 Pages 2006
Hydrogen Bonding Markedly Reduces the pK of Buried Carboxyl Groups in Proteins Fulltext Access 11 Pages 2006
Structure of a Hyper-cleavable Monomeric Fragment of Phage λ Repressor Containing the Cleavage Site Region Fulltext Access 11 Pages 2006
Opening of Holes in Liposomal Membranes Is Induced by Proteins Possessing the FERM Domain Fulltext Access 11 Pages 2006
Rapid Kinetics of Protein–Nucleic Acid Interaction is a Major Component of HIV-1 Nucleocapsid Protein’s Nucleic Acid Chaperone Function Fulltext Access 11 Pages 2006
The Evolution of Catalytic Efficiency and Substrate Promiscuity in Human Theta Class 1-1 Glutathione Transferase Fulltext Access 11 Pages 2006
Crystal Structure of the Translocation ATPase SecA from Thermus thermophilus Reveals a Parallel, Head-to-Head Dimer Fulltext Access 11 Pages 2006
A Mutation in the S-switch Region of the Runt Domain Alters the Dynamics of an Allosteric Network Responsible for CBFβ Regulation Fulltext Access 11 Pages 2006
A Conserved Base-pair between tRNA and 23 S rRNA in the Peptidyl Transferase Center Is Important for Peptide Release Fulltext Access 11 Pages 2006
Physical and Functional Interactions between the Prostate Suppressor Homeoprotein NKX3.1 and Serum Response Factor Fulltext Access 11 Pages 2006
The UAA/GAN Internal Loop Motif: A New RNA Structural Element that Forms a Cross-strand AAA Stack and Long-range Tertiary Interactions Fulltext Access 11 Pages 2006
Identification of the Core Structure of Lysozyme Amyloid Fibrils by Proteolysis Fulltext Access 11 Pages 2006
Arylamine N-acetyltransferase Aggregation and Constitutive Ubiquitylation Fulltext Access 11 Pages 2006
Energetics and Kinetics of Cooperative Cofilin–Actin Filament Interactions Fulltext Access 11 Pages 2006