Histamine-induced ion secretion across rat distal colon: Involvement of histamine H1 and H2 receptors Fulltext Access 10 Pages 2006
GEA3162, a nitric oxide-releasing agent, activates non-store-operated Ca2+ entry and inhibits store-operated Ca2+ entry pathways in neutrophils through thiol oxidation Fulltext Access 10 Pages 2006
The tachykinin NK3 receptor antagonist SR142801 blocks the behavioral effects of cocaine in marmoset monkeys Fulltext Access 10 Pages 2006
Targeting cytosolic phospholipase A2 by arachidonyl trifluoromethyl ketone prevents chronic inflammation in mice Fulltext Access 10 Pages 2006
Effects of bezafibrate, PPAR pan-agonist, and GW501516, PPARδ agonist, on development of steatohepatitis in mice fed a methionine- and choline-deficient diet Fulltext Access 10 Pages 2006
Neurogenic secretion mediated by the purinergic P2Y1 receptor in guinea-pig small intestine Fulltext Access 10 Pages 2006
Characterization of adenosine receptors in the human bladder carcinoma T24 cell line Fulltext Access 10 Pages 2006
A comparative study of the action of tolperisone on seven different voltage dependent sodium channel isoforms Fulltext Access 10 Pages 2006
Importance of acyl-coenzyme A:cholesterol acyltransferase 1/2 dual inhibition for anti-atherosclerotic potency of pactimibe Fulltext Access 10 Pages 2006
Evidence of COX-2 independent induction of apoptosis and cell cycle block in human colon carcinoma cells after S- or R-ibuprofen treatment Fulltext Access 10 Pages 2006
Sympathetic neurotransmission in the rat testicular capsule: Functional characterization and identification of mRNA encoding α1-adrenoceptor subtypes Fulltext Access 10 Pages 2006
Multiple mechanisms of hypocholesterolemic action of pactimibe, a novel acyl-coenzyme A:cholesterol acyltransferase inhibitor Fulltext Access 10 Pages 2006
Group III metabotropic glutamate receptor-mediated, chemically induced long-term depression differentially affects cell viability in the hippocampus Fulltext Access 10 Pages 2006
Paradoxical nifedipine facilitation of 45Ca uptake into rat hippocampal synaptosomes Fulltext Access 10 Pages 2006
Nicotine-induced upregulation of human neuronal nicotinic α7-receptors is potentiated by modulation of cAMP and PKC in SH-EP1-hα7 cells Fulltext Access 10 Pages 2006
Antiallergic drugs, azelastine hydrochloride and epinastine hydrochloride, inhibit ongoing IgE secretion of rat IgE-producing hybridoma FE-3 cells Fulltext Access 10 Pages 2006
A combined marble burying–locomotor activity test in mice: A practical screening test with sensitivity to different classes of anxiolytics and antidepressants Fulltext Access 10 Pages 2006
Arachidonyl-2′-chloroethylamide, a highly selective cannabinoid CB1 receptor agonist, enhances the anticonvulsant action of valproate in the mouse maximal electroshock-induced seizure model Fulltext Access 10 Pages 2006
Tubulin ligands suggest a microtubule–NADPH oxidase relationship in postischemic cardiomyocytes Fulltext Access 10 Pages 2006
The novel histone deacetylase inhibitor BML-210 exerts growth inhibitory, proapoptotic and differentiation stimulating effects on the human leukemia cell lines Fulltext Access 10 Pages 2006
Pharmacological characteristics of endothelium-derived hyperpolarizing factor-mediated relaxation of small mesenteric arteries from db/db mice Fulltext Access 10 Pages 2006
Determination of key amino acids implicated in the actions of allosteric modulation by 3,3′-difluorobenzaldazine on rat mGlu5 receptors Fulltext Access 10 Pages 2006
Characterisation of CGRP receptors in human and porcine isolated coronary arteries: Evidence for CGRP receptor heterogeneity Fulltext Access 10 Pages 2006
Molecular identification and functional characterization of a temperature-sensitive transient receptor potential channel (TRPM8) from canine Fulltext Access 10 Pages 2006
Dihydrocucurbitacin B, isolated from Cayaponia tayuya, reduces damage in adjuvant-induced arthritis Fulltext Access 10 Pages 2006
Effect of orally administered rolipram, a phosphodiesterase 4 inhibitor, on a mouse model of the dermatitis caused by 2,4,6-trinitro-1-chlorobenzene (TNCB)-repeated application Fulltext Access 10 Pages 2006
Heterologous desensitization is evoked by both agonist and antagonist stimulation of the human 5-HT7 serotonin receptor Fulltext Access 10 Pages 2006
Changes in pH differently affect the binding properties of histamine H1 receptor antagonists Fulltext Access 10 Pages 2006
Can P-glycoprotein influence the bioavailability of iminosugar-based glucosylceramide synthase inhibitors? Fulltext Access 10 Pages 2006
Inhibition of (S)-armepavine from Nelumbo nucifera on autoimmune disease of MRL/MpJ-lpr/lpr mice Fulltext Access 10 Pages 2006
Dissociation between post-surgical pain behaviors and spinal Fos-like immunoreactivity in the rat Fulltext Access 10 Pages 2006
Effect of co-administration of subchronic lithium pretreatment and acute MAO inhibitors on extracellular monoamine levels and the expression of contextual conditioned fear in rats Fulltext Access 10 Pages 2006
Prostacyclin therapy increases right ventricular capillarisation in a model for flow-associated pulmonary hypertension Fulltext Access 10 Pages 2006
Novel non-systemic inhibitor of ileal apical Na+-dependent bile acid transporter reduces serum cholesterol levels in hamsters and monkeys Fulltext Access 10 Pages 2006
In vitro and in vivo pharmacological characterization of the nociceptin/orphanin FQ receptor ligand Ac-RYYRIK-ol Fulltext Access 10 Pages 2006
T-cadinol and calamenene induce dendritic cells from human monocytes and drive Th1 polarization Fulltext Access 10 Pages 2006
N-Allylsecoboldine as a novel agent prevents acute renal failure during endotoxemia Fulltext Access 10 Pages 2006
Polymyxin B immobilized column is effective for hydrochloric acid-induced lung injury in rats Fulltext Access 10 Pages 2006
Bradykinin augments EGF-induced airway smooth muscle proliferation by activation of conventional protein kinase C isoenzymes Fulltext Access 10 Pages 2006
Effects of a selective melanin-concentrating hormone 1 receptor antagonist on food intake and energy homeostasis in diet-induced obese mice Fulltext Access 10 Pages 2006
Partial agonist properties of the antipsychotics SSR181507, aripiprazole and bifeprunox at dopamine D2 receptors: G protein activation and prolactin release Fulltext Access 10 Pages 2006
Novel excitatory neuropeptides isolated from a prosobranch gastropod, Thais clavigera: The molluscan counterpart of the annelidan GGNG peptides Fulltext Access 10 Pages 2006
Melanocortin peptide therapeutics: Historical milestones, clinical studies and commercialization Fulltext Access 10 Pages 2006
The role of polyamines in glucagon-like peptide-2 prevention of TPN-induced gut hypoplasia Fulltext Access 10 Pages 2006
Pharmacokinetics, toxicity of nasal cilia and immunomodulating effects in Sprague–Dawley rats following intranasal delivery of thymopentin with or without absorption enhancers Fulltext Access 10 Pages 2006
Expression of pituitary adenylate cyclase activating peptide in the uterine cervix, lumbosacral dorsal root ganglia and spinal cord of rats during pregnancy Fulltext Access 10 Pages 2006
Rat NPFF1 receptor-mediated signaling: functional comparison of neuropeptide FF (NPFF), FMRFamide and PFR(Tic)amide Fulltext Access 10 Pages 2006
Modulatory roles of the NPFF system in pain mechanisms at the spinal level Fulltext Access 10 Pages 2006
Molecular dissection of venom from Chinese scorpion Mesobuthus martensii: Identification and characterization of four novel disulfide-bridged venom peptides Fulltext Access 10 Pages 2006
Ion channel formation by Alzheimer's disease amyloid β-peptide (Aβ40) in unilamellar liposomes is determined by anionic phospholipids Fulltext Access 10 Pages 2006
Newly identified water-borne protein pheromones interact with attractin to stimulate mate attraction in Aplysia Fulltext Access 10 Pages 2006
Proctolin-like immunoreactivity in the central and peripheral nervous systems of the locust, Locusta migratoria Fulltext Access 10 Pages 2006
Degradation profile of [His7]-corazonin in the hemolymph of the desert locust Schistocerca gregaria Fulltext Access 10 Pages 2006
Apidaecin-type peptides: Biodiversity, structure–function relationships and mode of action Fulltext Access 10 Pages 2006
The hypothalamic paraventricular nucleus is not essential for orexigenic NPY or anorexigenic melanocortin action Fulltext Access 10 Pages 2006
Interaction of the tachykinin NK3 receptor agonist senktide with behavioral effects of cocaine in marmosets (Callithrix penicillata) Fulltext Access 10 Pages 2006
Backbone cyclic pheromone biosynthesis activating neuropeptide (PBAN) antagonists: Inhibition of melanization in the moth Spodoptera littoralis (Insecta, Lepidoptera) Fulltext Access 10 Pages 2006
Hemorphin and hemorphin-like peptides isolated from dog pancreas and sheep brain are able to potentiate bradykinin activity in vivo Fulltext Access 10 Pages 2006
VIP provides cellular protection through a specific splice variant of the PACAP receptor: A new neuroprotection target Fulltext Access 10 Pages 2006
Functional characterization of the modified melanocortin peptides responsible for ligand selectivity at the human melanocortin receptors Fulltext Access 10 Pages 2006
Antibacterial activity of linear peptides spanning the carboxy-terminal β-sheet domain of arthropod defensins Fulltext Access 10 Pages 2006
Improvement of cyclic decapeptides against plant pathogenic bacteria using a combinatorial chemistry approach Fulltext Access 10 Pages 2006
Agmatine and a cannabinoid agonist, WIN 55212-2, interact to produce a hypothermic synergy Fulltext Access 10 Pages 2006
Synergistic antinociceptive effects of anandamide, an endocannabinoid, and nonsteroidal anti-inflammatory drugs in peripheral tissue: A role for endogenous fatty-acid ethanolamides? Fulltext Access 10 Pages 2006
Cholesterol depletion reduces serotonin binding and signaling via human 5-HT7(a) receptors Fulltext Access 10 Pages 2006
MEK inhibition exacerbates ischemic calcium imbalance and neuronal cell death in rat cortical cultures Fulltext Access 10 Pages 2006
Identification of adipocyte differentiation-related regulatory element for adrenomedullin gene repression (ADRE-AR) in 3T3-L1 cells Fulltext Access 10 Pages 2006
Aplindore (DAB-452), a high affinity selective dopamine D2 receptor partial agonist Fulltext Access 10 Pages 2006
Pituitary adenylate cyclase-activating peptide (PACAP): Assessment of dipeptidyl peptidase IV degradation, insulin-releasing activity and antidiabetic potential Fulltext Access 10 Pages 2006
Ovarian jelly-peptides (OJPs), a new family of regulatory peptides identified in the cephalopod Sepia officinalis Fulltext Access 10 Pages 2006
Molecular cloning and characterization of FGLamide allatostatin gene from the prawn, Macrobrachium rosenbergii Fulltext Access 10 Pages 2006
Structure–activity studies of new melanocortin peptides containing an aromatic amino acid at the N-terminal position Fulltext Access 10 Pages 2006
Melanocyte stimulating hormone peptides inhibit TNF-α signaling in human dermal fibroblast cells Fulltext Access 10 Pages 2006
Interactions between gut peptides and the central melanocortin system in the regulation of energy homeostasis Fulltext Access 10 Pages 2006
The imidazoline I2-site ligands BU 224 and 2-BFI inhibit MAO-A and MAO-B activities, hydrogen peroxide production, and lipolysis in rodent and human adipocytes Fulltext Access 11 Pages 2006
Simvastatin inhibits the migration and adhesion of monocytic cells and disorganizes the cytoskeleton of activated endothelial cells Fulltext Access 11 Pages 2006
Long-term angiotensin II AT1 receptor inhibition produces adipose tissue hypotrophy accompanied by increased expression of adiponectin and PPARγ Fulltext Access 11 Pages 2006
Functional interaction between α2-adrenoceptors, μ- and κ-opioid receptors in the guinea pig myenteric plexus: Effect of chronic desipramine treatment Fulltext Access 11 Pages 2006
In-vitro experimental models for the risk assessment of antibiotic-induced QT prolongation Fulltext Access 11 Pages 2006
Effects of ciclamilast, a new PDE 4 PDE4 inhibitor, on airway hyperresponsiveness, PDE4D expression and airway inflammation in a murine model of asthma Fulltext Access 11 Pages 2006
SB-399885 is a potent, selective 5-HT6 receptor antagonist with cognitive enhancing properties in aged rat water maze and novel object recognition models Fulltext Access 11 Pages 2006
Depolarization preconditioning produces cytoprotection against veratridine-induced chromaffin cell death Fulltext Access 11 Pages 2006
Long lasting effects of prenatal exposure to deltamethrin on cerebral and hepatic cytochrome P450s and behavioral activity in rat offspring Fulltext Access 11 Pages 2006
Modulation by homocysteine of the iberiotoxin-sensitive, Ca2+-activated K+ channels of porcine coronary artery smooth muscle cells Fulltext Access 11 Pages 2006
In vivo versus in vitro comparison of swine cardiac performance: Induction of cardiodepression with halothane Fulltext Access 11 Pages 2006
Biphosphinic palladacycle complex mediates lysosomal-membrane permeabilization and cell death in K562 leukaemia cells Fulltext Access 11 Pages 2006