Original ResearchABVD or BEACOPPbaseline along with involved-field radiotherapy in early-stage Hodgkin Lymphoma with risk factors: Results of the European Organisation for Research and Treatment of Cancer (EORTC)-Groupe d'Ãtude des Lymphomes de l'Adult Fulltext Access 11 Pages 2017
Original ResearchA prediction model for treatment decisions in high-grade extremity soft-tissue sarcomas: Personalised sarcoma care (PERSARC) Fulltext Access 11 Pages 2017
ReviewSurvival of patients with advanced metastatic melanoma: the impact of novel therapies-update 2017 Fulltext Access 11 Pages 2017
Original ResearchDiagnostic value of whole body diffusion-weighted MRI compared to computed tomography for pre-operative assessment of patients suspected for ovarian cancer Fulltext Access 11 Pages 2017
Original ResearchA randomised phase II study of continuous versus stop-and-go S-1 plus oxaliplatin following disease stabilisation in first-line chemotherapy in patients with metastatic gastric cancer Fulltext Access 11 Pages 2017
Carboplatin versus two doses of cisplatin in combination with gemcitabine in the treatment of advanced non-small-cell lung cancer: Results from a British Thoracic Oncology Group randomised phase III trial Fulltext Access 11 Pages 2017
Original ResearchThree-year pooled analysis of factors associated with clinical outcomes across dabrafenib and trametinib combination therapy phase 3 randomised trials Fulltext Access 11 Pages 2017
Clinical TrialGeriatric factors analyses from FFCD 2001-02 phase III study of first-line chemotherapy for elderly metastatic colorectal cancer patients Fulltext Access 11 Pages 2017
Health-related quality of life in patients with locally recurrent or metastatic breast cancer treated with etirinotecan pegol versus treatment of physician's choice: Results from the randomised phase III BEACON trial Fulltext Access 11 Pages 2017
ReviewThe roles of oncogenic miRNAs and their therapeutic importance in breast cancer Fulltext Access 11 Pages 2017
Original ResearchPrevalence of immune-related systemic adverse events in patients treated with anti-Programmed cell Death 1/anti-Programmed cell Death-Ligand 1 agents: A single-centre pharmacovigilance database analysis Fulltext Access 11 Pages 2017
ReviewLinking uterine serous carcinoma to BRCA1/2-associated cancer syndrome: A meta-analysis and case report Fulltext Access 11 Pages 2017
ReviewPhase-II trials in osteosarcoma recurrences: A systematic review of past experience Fulltext Access 11 Pages 2017
Original ResearchAn increase in BAG-1 by PD-L1 confers resistance to tyrosine kinase inhibitor in non-small cell lung cancer via persistent activation of ERK signalling Fulltext Access 11 Pages 2017
Original ResearchSecond malignant neoplasms after childhood non-central nervous system embryonal tumours in North America: AÂ population-based study Fulltext Access 11 Pages 2017
Original ResearchHealth-related quality of life results from the PRODIGE 5/ACCORD 17 randomised trial of FOLFOX versus fluorouracil-cisplatin regimen in oesophageal cancer Fulltext Access 11 Pages 2017
Pro-inflammatory fatty acid profile and colorectal cancer risk: A Mendelian randomisation analysis Fulltext Access 11 Pages 2017
Original ResearchSex differences in cancer risk and survival: A Swedish cohort study Fulltext Access 11 Pages 2017
Original ResearchImpact of BRAF and RAS mutations on first-line efficacy of FOLFIRI plus cetuximab versus FOLFIRI plus bevacizumab: analysis of the FIRE-3 (AIO KRK-0306) study Fulltext Access 11 Pages 2017
Original ResearchA phase IB dose-escalation study of the safety and pharmacokinetics of pictilisib in combination with either paclitaxel and carboplatin (with or without bevacizumab) or pemetrexed and cisplatin (with or without bevacizumab) in patients wi Fulltext Access 11 Pages 2017
Review(Neo)adjuvant treatment in localised soft tissue sarcoma: The unsolved affair Fulltext Access 11 Pages 2017
Original ResearchENGOT-ov-6/TRINOVA-2: Randomised, double-blind, phase 3 study of pegylated liposomal doxorubicin plus trebananib or placebo in women with recurrent partially platinum-sensitive or resistant ovarian cancer Fulltext Access 11 Pages 2017
Original ResearchEfficacy of FOLFOXIRI plus bevacizumab in liver-limited metastatic colorectal cancer: A pooled analysis of clinical studies by Gruppo Oncologico del Nord Ovest Fulltext Access 11 Pages 2017
The prognostic benefit of tumour-infiltrating Natural Killer cells in endometrial cancer is dependent on concurrent overexpression of Human Leucocyte Antigen-E in the tumour microenvironment Fulltext Access 11 Pages 2017
ReviewReprogramming acute myeloid leukemia into sensitivity for retinoic-acid-driven differentiation Fulltext Access 12 Pages 2017
Casiopeina III-Ea, a copper-containing small molecule, inhibits the in vitro growth of primitive hematopoietic cells from chronic myeloid leukemia Fulltext Access 12 Pages 2017
Nivolumab and pembrolizumab: Monoclonal antibodies against programmed cell death-1 (PD-1) that are interchangeable Fulltext Access 12 Pages 2017
Loss of Cbl-PI3K interaction modulates the periosteal response to fracture by enhancing osteogenic commitment and differentiation Fulltext Access 12 Pages 2017
ImmunotherapyHerpes simplex virus type 1 (HSV-1) specific T-cell generation from HLA-A1- and HLA-A2-positive donors for adoptive immunotherapy Fulltext Access 12 Pages 2017
Exercise initiated after the onset of insulin resistance improves trabecular microarchitecture and cortical bone biomechanics of the tibia in hyperphagic Otsuka Long Evans Tokushima Fatty rats Fulltext Access 12 Pages 2017
Development, functional characterization and validation of methodology for GMP-compliant manufacture of phagocytic macrophages: A novel cellular therapeutic for liver cirrhosis Fulltext Access 12 Pages 2017
Dendritic CellsDendritic cells infected by Ad-sh-SOCS1 enhance cytokine-induced killer (CIK) cell immunotherapeutic efficacy in cervical cancer models Fulltext Access 12 Pages 2017
Full Length ArticleBardet-Biedl syndrome 3 regulates the development of cranial base midline structures Fulltext Access 12 Pages 2017
Improving Survival of Patients With Hodgkin Lymphoma Over 4 Decades: Experience of the British National Lymphoma Investigation (BNLI) With 6834 Patients Fulltext Access 12 Pages 2017
CD56-enriched donor cell infusion after post-transplantation cyclophosphamide for haploidentical transplantation of advanced myeloid malignancies is associated with prompt reconstitution of mature natural killer cells and regulatory T cells with reduced i Fulltext Access 12 Pages 2017
Increase of IRF-1 gene expression and impairment of T regulatory cells suppression activity on patients with myelodysplastic syndrome: A longitudinal one-year study Fulltext Access 12 Pages 2017
Mechanisms of Resistance to FLT3 Inhibitors and the Role of the Bone Marrow Microenvironment Fulltext Access 12 Pages 2017
Apheresis data registration in WWA registry-10-year experience of our center Fulltext Access 12 Pages 2017
Mesenchymal stromal cells protect human cardiomyocytes from amyloid fibril damage Fulltext Access 12 Pages 2017
Ibrutinib as a bridge to transplant in high-risk chronic lymphocytic leukemia: A case report and review of the literature Fulltext Access 12 Pages 2017
Liver immunotolerance and hepatocellular carcinoma: Patho-physiological mechanisms and therapeutic perspectives Fulltext Access 12 Pages 2017
Ajmaline blocks INa and IKr without eliciting differences between Brugada syndrome patient and control human pluripotent stem cell-derived cardiac clusters Fulltext Access 12 Pages 2017
Identification of hereditary hemochromatosis pedigrees and a novel SLC40A1 mutation in Chinese population Fulltext Access 12 Pages 2017
Defining precision: The precision medicine initiative trials NCI-MPACT and NCI-MATCH Fulltext Access 12 Pages 2017
ECCO Essential Requirements for Quality Cancer Care: Soft Tissue Sarcoma in Adults and Bone Sarcoma. A critical review Fulltext Access 12 Pages 2017
Targeting KRAS mutated non-small cell lung cancer: A history of failures and a future of hope for a diverse entity Fulltext Access 12 Pages 2017
Regulatory effects of berberine on microRNome in Cancer and other conditions Fulltext Access 12 Pages 2017
FGFR a promising druggable target in cancer: Molecular biology and new drugs Fulltext Access 12 Pages 2017
MicroRNAs in glioblastoma pathogenesis and therapy: A comprehensive review Fulltext Access 12 Pages 2017
Compounding variants rescue the effect of a deleterious ADAMTS13 mutation in a child with severe congenital heart disease Fulltext Access 12 Pages 2017
ReviewModeling myeloproliferative neoplasms: From mutations to mouse models and back again Fulltext Access 12 Pages 2017
Original ResearchCytotoxic tumour-infiltrating T lymphocytes influence outcome in resected pancreatic ductal adenocarcinoma Fulltext Access 12 Pages 2017
Original ResearchPolicy and priorities for national cancer control planning in low- and middle-income countries: Lessons from the Association of Southeast Asian Nations (ASEAN) Costs in Oncology prospective cohort study Fulltext Access 12 Pages 2017
Original ResearchEGFR-independent Elk1/CIP2A signalling mediates apoptotic effect of an erlotinib derivative TD52 in triple-negative breast cancer cells Fulltext Access 12 Pages 2017
Original ResearchInduction chemotherapy followed by radiotherapy for larynx preservation in advanced laryngeal and hypopharyngeal cancer: Outcome prediction after one cycle induction chemotherapy by a score based on clinical evaluation, computed tomograp Fulltext Access 12 Pages 2017
Original ResearchBaseline β-catenin, programmed death-ligand 1 expression and tumour-infiltrating lymphocytes predict response and poor prognosis in BRAF inhibitor-treated melanoma patients Fulltext Access 12 Pages 2017
ReviewQuality of life in survivors of oropharyngeal cancer: AÂ systematic review and meta-analysis of 1366 patients Fulltext Access 12 Pages 2017
ReviewRationale for stimulator of interferon genes-targeted cancer immunotherapy Fulltext Access 12 Pages 2017
Original ResearchThe proportion of circulating CD45RO+CD8+ memory T cells is correlated with clinical response in melanoma patients treated with ipilimumab Fulltext Access 12 Pages 2017
Original ResearchBreast cancer in young women and prognosis: How important are proliferation markers? Fulltext Access 12 Pages 2017
Microenvironment and NicheA novel dual inhibitor of microtubule and Bruton's tyrosine kinase inhibits survival of multiple myeloma and osteoclastogenesis Fulltext Access 12 Pages 2017
Interleukin-1β as emerging therapeutic target in hematological malignancies and potentially in their complications Fulltext Access 12 Pages 2017
BiologyTargeting the Canonical Nuclear Factor-κB Pathway with a High-Potency IKK2 Inhibitor Improves Outcomes in a Mouse Model of Idiopathic Pneumonia Syndrome Fulltext Access 12 Pages 2017
Reduced-Intensity Conditioning with Busulfan, Fludarabine, and Antithymocyte Globulin for Hematopoietic Cell Transplantation from Unrelated or Haploidentical Family Donors in Patients with Acute Myeloid Leukemia in Remission Fulltext Access 12 Pages 2017
ReviewChimeric Antigen Receptor T Cells and Hematopoietic Cell Transplantation: How Not to Put the CART Before the Horse Fulltext Access 12 Pages 2017
How do we measure MRD in ALL and how should measurements affect decisions. Re: Treatment and prognosis? Fulltext Access 12 Pages 2017
CD146 (MCAM) in human cs-DLK1â/cs-CD34+ adipose stromal/progenitor cells Fulltext Access 12 Pages 2017
Unlocking the chromatin of adenoid cystic carcinomas using HDAC inhibitors sensitize cancer stem cells to cisplatin and induces tumor senescence Fulltext Access 12 Pages 2017
Physicochemical characterization and immunological properties of Pichia pastoris based HPV16L1 and 18L1 virus like particles Fulltext Access 12 Pages 2017
Neoadjuvant chemoradiotherapy of the rectal carcinoma - The correlation between the findings on the restaging multiparametric 3T MRI scanning and the surgical findings Fulltext Access 12 Pages 2017
Health-related quality of life results from the phase III CheckMate 067 study Fulltext Access 12 Pages 2017
MLL-AF4 binds directly to a BCL-2 specific enhancer and modulates H3K27 acetylation Fulltext Access 12 Pages 2017
ReviewApplication of vitamin D and vitamin D analogs in acute myelogenous leukemia Fulltext Access 12 Pages 2017
Stem CellsHIF-1α-stabilizing agent FG-4497 rescues human CD34+ cell mobilization in response to G-CSF in immunodeficient mice Fulltext Access 12 Pages 2017
Original ResearchFirst-in-man dose escalation and pharmacokinetic study of CAP7.1, a novel prodrug of etoposide, in adults with refractory solid tumours Fulltext Access 12 Pages 2017
Original ResearchExploring the clonal evolution of CD133/aldehyde-dehydrogenase-1 (ALDH1)-positive cancer stem-like cells from primary to recurrent high-grade serous ovarian cancer (HGSOC). A study of the Ovarian Cancer Therapy-Innovative Models Prolong Fulltext Access 12 Pages 2017
First-line panitumumab plus FOLFOX4 or FOLFIRI in colorectal cancer with multiple or unresectable liver metastases: A randomised, phase II trial (PLANET-TTD) Fulltext Access 12 Pages 2017
Original ResearchP53 and MITF/Bcl-2 identified as key pathways in the acquired resistance of NRAS-mutant melanoma to MEK inhibition Fulltext Access 12 Pages 2017
Original ResearchInfluence of age and comorbidity on prognosis and application of adjuvant chemotherapy in elderly Japanese patients with colorectal cancer: A retrospective multicentre study Fulltext Access 12 Pages 2017
The cornerstone K-RAS mutation in pancreatic adenocarcinoma: From cell signaling network, target genes, biological processes to therapeutic targeting Fulltext Access 13 Pages 2017
Urothelial CellsThe anti-tumor effect of intravesical administration of normal urothelial cells on bladder cancer Fulltext Access 13 Pages 2017
Impact of local injection of brain-derived neurotrophic factor-expressing mesenchymal stromal cells (MSCs) combined with intravenous MSC delivery in a canine model of chronic spinal cord injury Fulltext Access 13 Pages 2017
Understanding c-MET signalling in squamous cell carcinoma of the head & neck Fulltext Access 13 Pages 2017
Therapeutic strategies for locally recurrent and metastatic de-differentiated liposarcoma with herpes simplex virus-thymidine kinase-expressing mesenchymal stromal cells Fulltext Access 13 Pages 2017
Optimization of cGMP purification and expansion of umbilical cord blood-derived T-regulatory cells in support of first-in-human clinical trials Fulltext Access 13 Pages 2017
Establishment of induced pluripotent stem cell line (ZZUi010-A) from an Alzheimer's disease patient carrying an APP gene mutation Fulltext Access 13 Pages 2017
Review ArticleIntravenous mesenchymal stromal cell therapy for inflammatory bowel disease: Lessons from the acute graft versus host disease experience Fulltext Access 13 Pages 2017
PARP inhibitors alone and in combination with other biological agents in homologous recombination deficient epithelial ovarian cancer: From the basic research to the clinic Fulltext Access 13 Pages 2017
ImmunotherapyAdjuvant combination therapy with gemcitabine and autologous γδ T-cell transfer in patients with curatively resected pancreatic cancer Fulltext Access 13 Pages 2017
Quality of Life and Adherence to Therapy in Patients With Chronic Myeloid Leukemia Treated With Nilotinib as a Second-Line Therapy: AÂ Multicenter Prospective Observational Study Fulltext Access 13 Pages 2017
ECCO Essential Requirements for Quality Cancer Care: Colorectal Cancer. A critical review Fulltext Access 13 Pages 2017
Pretreatment with IL-1β enhances proliferation and chondrogenic potential of synovium-derived mesenchymal stem cells Fulltext Access 13 Pages 2017
Efficacy and safety of olanzapine for the prevention of chemotherapy-induced nausea and vomiting: A systematic review and meta-analysis Fulltext Access 13 Pages 2017