2,4-Dimethoxyphenylsemicarbazones with anticonvulsant activity against three animal models of seizures: Synthesis and pharmacological evaluation Fulltext Access 7 Pages 2006
Synthesis and biological evaluation of new spin-labeled derivatives of podophyllotoxin Fulltext Access 7 Pages 2006
Novel fluorescent markers for hypoxic cells of naphthalimides with two heterocyclic side chains for bioreductive binding Fulltext Access 7 Pages 2006
Synthesis of 7-oxo-7H-naphtho[1,2,3-de]quinoline derivatives as potential anticancer agents active on multidrug resistant cell lines Fulltext Access 7 Pages 2006
Baicalein is a potent in vitro inhibitor against both reticulocyte 15-human and platelet 12-human lipoxygenases Fulltext Access 7 Pages 2006
Photodynamic inactivation of Escherichia coli immobilized on agar surfaces by a tricationic porphyrin Fulltext Access 7 Pages 2006
Monometallic complexes of 1,4,7,10-tetraazacyclododecane containing an imidazolium side: Synthesis, characterization, and their interaction with plasmid DNA Fulltext Access 7 Pages 2006
3′-Fluoro-3′-deoxy-5′-noraristeromycin derivatives: Synthesis and antiviral analysis Fulltext Access 7 Pages 2006
Design, synthesis, and biological evaluation of 1,2,3-trisubstituted-1,4-dihydrobenzo[g]quinoxaline-5,10-diones and related compounds as antifungal and antibacterial agents Fulltext Access 7 Pages 2006
Oxazolones: New tyrosinase inhibitors; synthesis and their structure–activity relationships Fulltext Access 7 Pages 2006
Synthesis and biological evaluation of 5-arylamino-1H-benzo[d]imidazole-4,7-diones as inhibitor of endothelial cell proliferation Fulltext Access 7 Pages 2006
Self-aggregation of synthetic zinc chlorophyll derivative possessing a perfluoroalkyl group in a fluorinated solvent Fulltext Access 7 Pages 2006
Novel α-aminophosphonic acids. Design, characterization, and biological activity Fulltext Access 7 Pages 2006
Effective discrimination of antimalarial potency of artemisinin compounds based on quantum chemical calculations of their reaction mechanism Fulltext Access 7 Pages 2006
Structure–activity relationships of substituted N-benzyl piperidines in the GBR series: Synthesis of 4-(2-(bis(4-fluorophenyl)methoxy)ethyl)-1-(2-trifluoromethylbenzyl)piperidine, an allosteric modulator of the serotonin transporter Fulltext Access 7 Pages 2006
Synthesis of 8-geranyloxypsoralen analogues and their evaluation as inhibitors of CYP3A4 Fulltext Access 7 Pages 2006
Synthesis and biological evaluation of phosphonated dihydroisoxazole nucleosides Fulltext Access 7 Pages 2006
Synthesis and biological evaluation of (2S)- and (2R)-2-(3′-phosphonobicyclo[1.1.1]pentyl)glycines as novel group III selective metabotropic glutamate receptor ligands Fulltext Access 7 Pages 2006
Synthesis and high-throughput evaluation of triskelion uracil libraries for inhibition of human dUTPase and UNG2 Fulltext Access 7 Pages 2006
Synthesis of Sansalvamide A derivatives and their cytotoxicity in the MSS colon cancer cell line HT-29 Fulltext Access 7 Pages 2006
A 9-cis-epoxycarotenoid dioxygenase inhibitor for use in the elucidation of abscisic acid action mechanisms Fulltext Access 7 Pages 2006
Metaanalysis of Acustimulation Effects on Postoperative Nausea and Vomiting in Children Fulltext Access 7 Pages 2006
Synthesis and evaluation of anilinohexafluoroisopropanols as activators/modulators of LXRα and β Fulltext Access 7 Pages 2006
Selectively guanidinylated derivatives of neamine. Syntheses and inhibition of anthrax lethal factor protease Fulltext Access 7 Pages 2006
Preparation of 1-(3-aminobenzo[d]isoxazol-5-yl)-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-ones as potent, selective, and efficacious inhibitors of coagulation factor Xa Fulltext Access 7 Pages 2006
Homo-cysteinyl peptide inhibitors of the L1 metallo-β-lactamase, and SAR as determined by combinatorial library synthesis Fulltext Access 7 Pages 2006
Development of a novel albumin-binding prodrug that is cleaved by urokinase-type-plasminogen activator (uPA) Fulltext Access 7 Pages 2006
Pyrrolidine bis-cyclic guanidines with antimicrobial activity against drug-resistant Gram-positive pathogens identified from a mixture-based combinatorial library Fulltext Access 7 Pages 2006
Solid-phase synthesis and structure-activity relationships of novel biarylethers as melanin-concentrating hormone receptor-1 antagonists Fulltext Access 7 Pages 2006
Structure–activity studies on the protection of Trimetazidine derivatives modified with nitroxides and their precursors from myocardial ischemia–reperfusion injury Fulltext Access 7 Pages 2006
Improved replicon cellular activity of non-nucleoside allosteric inhibitors of HCV NS5B polymerase: From benzimidazole to indole scaffolds Fulltext Access 7 Pages 2006
Synthesis of 1,2,4-trioxepanes via application of thiol-olefin Co-oxygenation methodology Fulltext Access 7 Pages 2006
Rapid synthesis of 4-benzylidene and 4-[bis-(4-methoxyphenyl)-methylene-2-substituted phenyl-benzopyrans as potential selective estrogen receptor modulators (SERMs) using McMurry coupling reaction Fulltext Access 7 Pages 2006
99mTc-labeling of colchicine using [99mTc(CO)3(H2O)3]+ and [99mTcN]2+ core for the preparation of potential tumor-targeting agents Fulltext Access 7 Pages 2006
Metabolic conversion of 24-methyl-Δ25-cholesterol to 24-methylcholesterol in higher plants Fulltext Access 7 Pages 2006
Steroidal saponins from Calamus insignis, and their cell growth and cell cycle inhibitory activities Fulltext Access 7 Pages 2006
Solid phase combinatorial synthesis of benzothiazoles and evaluation of topoisomerase II inhibitory activity Fulltext Access 7 Pages 2006
C-Glycoside analogues of β-galactosylceramide with a simple ceramide substitute: Synthesis and binding to HIV-1 gp120 Fulltext Access 7 Pages 2006
QSAR study on para-substituted aromatic sulfonamides as carbonic anhydrase II inhibitors using topological information indices Fulltext Access 7 Pages 2006
Synthesis and in vitro anti-hepatitis B virus activities of some ethyl 6-bromo-5-hydroxy-1H-indole-3-carboxylates Fulltext Access 7 Pages 2006
Computational evidence for the ligand selectivity to the α4β2 and α3β4 nicotinic acetylcholine receptors Fulltext Access 7 Pages 2006
Cytotoxicity of abietane diterpenoids from Perovskia abrotanoides and of their semisynthetic analogues Fulltext Access 7 Pages 2006
Anticonvulsant evaluation and mechanism of action of benzylamino enaminones Fulltext Access 7 Pages 2006
Synthesis and biological evaluation of linear phenylethynylbenzenesulfonamide regioisomers as cyclooxygenase-1/-2 (COX-1/-2) inhibitors Fulltext Access 7 Pages 2006
Synthesis, cannabinoid receptor activity, and enzymatic stability of reversed amide derivatives of arachidonoyl ethanolamide Fulltext Access 7 Pages 2006
Effects on erythroid differentiation of platinum(II) complexes of synthetic bile acid derivatives Fulltext Access 7 Pages 2006
Synthesis and biological evaluation of 1,3-diphenylprop-2-en-1-ones possessing a methanesulfonamido or an azido pharmacophore as cyclooxygenase-1/-2 inhibitors Fulltext Access 7 Pages 2006
QSAR modeling of anti-invasive activity of organic compounds using structural descriptors Fulltext Access 7 Pages 2006
New quinoxaline 1,4-di-N-oxides. Part 1: Hypoxia-selective cytotoxins and anticancer agents derived from quinoxaline 1,4-di-N-oxides Fulltext Access 7 Pages 2006
Isolation and synthesis of analgesic and anti-inflammatory compounds from Ochna squarrosa L. Fulltext Access 7 Pages 2006
New biscoumarin derivatives-cytotoxicity and enzyme inhibitory activities Fulltext Access 7 Pages 2006
Synthesis and evaluation of a 3-position diastereomer of 1α,25-dihydroxy-2β-(3-hydroxypropoxy)vitamin D3 (ED-71) Fulltext Access 7 Pages 2006
Synthesis and immunosuppressive activity of new artemisinin derivatives. Part 2: 2-[12(β or α)-Dihydroartemisinoxymethyl(or 1′-ethyl)]phenoxyl propionic acids and esters Fulltext Access 7 Pages 2006
Discovery, structure–activity relationship study, and oral analgesic efficacy of cyproheptadine derivatives possessing N-type calcium channel inhibitory activity Fulltext Access 7 Pages 2006
A new dihydroxanthenone from a plant-associated strain of the fungus Chaetomium globosum demonstrates anticancer activity Fulltext Access 7 Pages 2006
5-Substituted-2,3-diphenyltetrahydrofurans: A new class of moderately selective COX-2 inhibitors Fulltext Access 7 Pages 2006
Influence of terminal branching on the transdermal permeation-enhancing activity in fatty alcohols and acids Fulltext Access 7 Pages 2006
Leaching potential of heavy metals (Cd, Ni, Pb, Cu and Zn) from acidic sandy soil amended with dolomite phosphate rock (DPR) fertilizers Fulltext Access 7 Pages 2006
Influence of static magnetic field on cadmium toxicity: Study of oxidative stress and DNA damage in rat tissues Fulltext Access 7 Pages 2006
Chemomodulatory effects of Terminalia chebula against nickel chloride induced oxidative stress and tumor promotion response in male Wistar rats Fulltext Access 7 Pages 2006
Influence of maternal dietary calcium levels on milk zinc, calcium and phosphorus contents and milk production in rats Fulltext Access 7 Pages 2006
Hypoglycemic potency of novel trivalent chromium in hyperglycemic insulin-deficient rats Fulltext Access 7 Pages 2006
The release of metals from metal-on-metal surface arthroplasty of the hip Fulltext Access 7 Pages 2006
Aluminium-induced injury to kidney proximal tubular cells: Effects on markers of oxidative damage Fulltext Access 7 Pages 2006
The effect of orally administered melatonin on tissue accumulation and toxicity of cadmium in mice Fulltext Access 7 Pages 2006
Synthesis and antiproliferative evaluation of certain pyrido[3,2-g]quinoline derivatives Fulltext Access 7 Pages 2006
Improving anti-trypanosomal activity of 3-aminoquinoxaline-2-carbonitrile N1,N4-dioxide derivatives by complexation with vanadium Fulltext Access 7 Pages 2006
DNA-binding affinities and sequence selectivity of quaternary benzophenanthridine alkaloids sanguinarine, chelerythrine, and nitidine Fulltext Access 7 Pages 2006
Enhancing effect of indirubin derivatives on 1,25-dihydroxyvitamin D3- and all-trans retinoic acid-induced differentiation of HL-60 leukemia cells Fulltext Access 7 Pages 2006
Synthesis and DNA cleavage activities of mononuclear macrocyclic polyamine zinc(II), copper(II), cobalt(II) complexes which linked with uracil Fulltext Access 7 Pages 2006
New progesterone receptor antagonists: Phosphorus-containing 11β-aryl-substituted steroids Fulltext Access 7 Pages 2006
2-(4,5-Dihydroimidazol-2-yl)benzimidazoles as highly selective imidazoline I2/adrenergic α2 receptor ligands Fulltext Access 7 Pages 2006
Synthesis and in vitro antimicrobial studies of medicinally important novel N-alkyl and N-sulfonyl derivatives of 1-[bis(4-fluorophenyl)-methyl]piperazine Fulltext Access 7 Pages 2006
Membrane interaction of amphotericin B as single-length assembly examined by solid state NMR for uniformly 13C-enriched agent Fulltext Access 7 Pages 2006
Comparative uptake, metabolism, and utilization of menaquinone-4 and phylloquinone in human cultured cell lines Fulltext Access 7 Pages 2006
The 5-substituted piperazine as a novel secondary pharmacophore greatly improving the physical properties of urea-based inhibitors of soluble epoxide hydrolase Fulltext Access 7 Pages 2006
Structures of new amphidinols with truncated polyhydroxyl chain and their membrane-permeabilizing activities Fulltext Access 7 Pages 2006
Do indicators of maternal iron status reflect placental iron status at delivery? Fulltext Access 7 Pages 2006
Structure–activity relationship for inhibition of 5α-reductase by triterpenoids isolated from Ganoderma lucidum Fulltext Access 7 Pages 2006
Synthesis of novel vasodilatory active nicotinate esters with amino acid function Fulltext Access 7 Pages 2006
Synthesis and evaluation of peptidic irreversible inhibitors of tissue transglutaminase Fulltext Access 7 Pages 2006
Structure of C-terminal fragment of merozoite surface protein-1 from Plasmodium vivax determined by homology modeling and molecular dynamics refinement Fulltext Access 7 Pages 2006
Interactions of some modified mono- and bis-β-cyclodextrins with bovine serum albumin Fulltext Access 7 Pages 2006
Synthesis and antibacterial activity of N-[2-[5-(methylthio)thiophen-2-yl]-2-oxoethyl] and N-[2-[5-(methylthio)thiophen-2-yl]-2-(oxyimino)ethyl]piperazinylquinolone derivatives Fulltext Access 7 Pages 2006
Isolation and characterization of a monoamine oxidase B selective inhibitor from tobacco smoke Fulltext Access 7 Pages 2006
Interaction of chromium(III) complex of chiral binaphthyl tetradentate ligand with DNA Fulltext Access 7 Pages 2006