Design, synthesis and biological evaluation of potential antibacterial butyrolactones Fulltext Access 11 Pages 2016
Discovery, pharmacology, and clinical profile of omadacycline, a novel aminomethylcycline antibiotic Fulltext Access 11 Pages 2016
Animal models in the pharmacokinetic/pharmacodynamic evaluation of antimicrobial agents Fulltext Access 11 Pages 2016
Identification of chemical constituents in two traditional Chinese medicine formulae by liquid chromatography-mass spectrometry and off-line nuclear magnetic resonance Fulltext Access 11 Pages 2016
Limited proteolysis and peptide mapping for comparability of biopharmaceuticals: An evaluation of repeatability, intra-assay precision and capability to detect structural change Fulltext Access 11 Pages 2016
Characterization of human metabolism and disposition of levo-tetrahydropalmatine: Qualitative and quantitative determination of oxidative and conjugated metabolites Fulltext Access 11 Pages 2016
Extended modified cubic B-spline algorithm for nonlinear Burgers' equation Fulltext Access 11 Pages 2016
Design, synthesis, and evaluation of hinge-binder tethered 1,2,3-triazolylsalicylamide derivatives as Aurora kinase inhibitors Fulltext Access 11 Pages 2016
Design, synthesis, and biological evaluation of a novel series of peripheral-selective noradrenaline reuptake inhibitors—Part 2 Fulltext Access 11 Pages 2016
Synthesis of alanyl nucleobase amino acids and their incorporation into proteins Fulltext Access 11 Pages 2016
Optimization of microchip-based electrophoresis for monoclonal antibody product quality analysis revealed needs for extra surfactants during denaturation Fulltext Access 11 Pages 2016
Simultaneous determination of buprenorphine, norbuprenorphine and naloxone in human plasma by liquid chromatography/tandem mass spectrometry Fulltext Access 11 Pages 2016
Chiral separation of tedizolid using charge single isomer derivatives of cyclodextrins by capillary electrokinetic chromatography Fulltext Access 11 Pages 2016
Practical method development for the separation of monoclonal antibodies and antibody-drug-conjugate species in hydrophobic interaction chromatography, part 1: optimization of the mobile phase Fulltext Access 11 Pages 2016
Quantitative structure-retention relationship of selected imidazoline derivatives on α1-acid glycoprotein column Fulltext Access 11 Pages 2016
The interaction of protamine nanocapsules with the intestinal epithelium: A mechanistic approach Fulltext Access 12 Pages 2016
Development of gellan gum containing formulations for transdermal drug delivery: Component evaluation and controlled drug release using temperature responsive nanogels Fulltext Access 12 Pages 2016
Drug discovery strategies to outer membrane targets in Gram-negative pathogens Fulltext Access 12 Pages 2016
Development and validation of a liquid chromatographic-tandem mass spectrometric method for the multiplexed quantification of etravirine, maraviroc, raltegravir, and rilpivirine in human plasma and tissue Fulltext Access 12 Pages 2016
New techniques of on-line biological sample processing and their application in the field of biopharmaceutical analysis Fulltext Access 12 Pages 2016
Development of a mechanism-based pharmacokinetic/pharmacodynamic model to characterize the thermoregulatory effects of serotonergic drugs in mice Fulltext Access 12 Pages 2016
Research paperFreezing and glass transitions upon cooling and warming and ice/freeze-concentration-solution morphology of emulsified aqueous citric acid Fulltext Access 12 Pages 2016
Transcutaneous immunization via rapidly dissolvable microneedles protects against hand-foot-and-mouth disease caused by enterovirus 71 Fulltext Access 12 Pages 2016
Recent advances in the discovery of heparanase inhibitors as anti-cancer agents Fulltext Access 12 Pages 2016
Good things come in small packages: Overcoming challenges to harness extracellular vesicles for therapeutic delivery Fulltext Access 12 Pages 2016
Integrin-binding elastin-like polypeptide as an in situ gelling delivery matrix enhances the therapeutic efficacy of adipose stem cells in healing full-thickness cutaneous wounds Fulltext Access 12 Pages 2016
Additive effects on the improvement of insecticidal activity: Design, synthesis, and insecticidal activity of novel pymetrozine derivatives Fulltext Access 12 Pages 2016
Design, synthesis, structure-activity relationships, and docking studies of pyrazole-containing derivatives as a novel series of potent glucagon receptor antagonists Fulltext Access 12 Pages 2016
Development of cyanopyridine-triazine hybrids as lead multitarget anti-Alzheimer agents Fulltext Access 12 Pages 2016
Ethylcellulose film coating of guaifenesin-loaded pellets: A comprehensive evaluation of the manufacturing process to prevent drug migration Fulltext Access 12 Pages 2016
Spectroscopic evaluation of a freeze-dried vaccine during an accelerated stability study Fulltext Access 12 Pages 2016
Nanoparticle tracking analysis of particle size and concentration detection in suspensions of polymer and protein samples: Influence of experimental and data evaluation parameters Fulltext Access 12 Pages 2016
Combining the single-walled carbon nanotubes with low voltage electrical stimulation to improve accumulation of nanomedicines in tumor for effective cancer therapy Fulltext Access 12 Pages 2016
Self-assembled ternary complexes stabilized with hyaluronic acid-green tea catechin conjugates for targeted gene delivery Fulltext Access 12 Pages 2016
The synthesis and biological evaluation of alkyl and benzyl naphthyridinium analogs of eupolauridine as potential antimicrobial and cytotoxic agents Fulltext Access 12 Pages 2016
Development and evaluation of oxaliplatin and irinotecan co-loaded liposomes for enhanced colorectal cancer therapy Fulltext Access 12 Pages 2016
Formulation of hydrophobic therapeutics with self-assembling peptide and amino acid: A new platform for intravenous drug delivery Fulltext Access 12 Pages 2016
Transcript-activated collagen matrix as sustained mRNA delivery system for bone regeneration Fulltext Access 12 Pages 2016
Synthesis and evaluation of novel serotonin 4 receptor radiotracers for single photon emission computed tomography Fulltext Access 12 Pages 2016
Chalcogen containing heterocyclic scaffolds: New hybrids with antitumoral activity Fulltext Access 12 Pages 2016
Enhancing backbone sampling in Monte Carlo simulations using internal coordinates normal mode analysis Fulltext Access 12 Pages 2016
In vitro antileukemic activity of novel adenosine derivatives bearing boron cluster modification Fulltext Access 12 Pages 2016
Design, synthesis, and evaluation of novel porcupine inhibitors featuring a fused 3-ring system based on the 'reversed' amide scaffold Fulltext Access 12 Pages 2016
Design, synthesis and Structure–activity relationship studies of new thiazole-based free fatty acid receptor 1 agonists for the treatment of type 2 diabetes Fulltext Access 12 Pages 2016
Vascularization strategies of engineered tissues and their application in cardiac regeneration Fulltext Access 12 Pages 2016
Cellular biodistribution of polymeric nanoparticles in the immune system Fulltext Access 12 Pages 2016
Simultaneous magnetic resonance imaging and pharmacokinetic analysis of intramuscular depots Fulltext Access 12 Pages 2016
Development of a drug delivery system for efficient alveolar delivery of a neutralizing monoclonal antibody to treat pulmonary intoxication to ricin Fulltext Access 12 Pages 2016
Phthalimido-thiazoles as building blocks and their effects on the growth and morphology of Trypanosoma cruzi Fulltext Access 12 Pages 2016
Toward overcoming cisplatin resistance via sterically hindered platinum(II) complexes Fulltext Access 12 Pages 2016
Synthesis and biological evaluation of a series of non-hemiacetal ester derivatives of artemisinin Fulltext Access 12 Pages 2016
Structure–activity relationship study of anticancer thymidine–quinoxaline conjugates under the low radiance of long wavelength ultraviolet light for photodynamic therapy Fulltext Access 12 Pages 2016
Discovery of novel sesquistilbene indanone analogues as potent anti-inflammatory agents Fulltext Access 12 Pages 2016
Applying the designed multiple ligands approach to inhibit dihydrofolate reductase and thioredoxin reductase for anti-proliferative activity Fulltext Access 12 Pages 2016
Design, synthesis of phenstatin/isocombretastatin-oxindole conjugates as antimitotic agents Fulltext Access 12 Pages 2016
Design, synthesis and biological evaluation of novel donepezil–coumarin hybrids as multi-target agents for the treatment of Alzheimer’s disease Fulltext Access 12 Pages 2016
Emerging targets and new small molecule therapies in Parkinson’s disease treatment Fulltext Access 12 Pages 2016
In-syringe reversed dispersive liquid–liquid microextraction for the evaluation of three important bioactive compounds of basil, tarragon and fennel in human plasma and urine samples Fulltext Access 12 Pages 2016
Structural peculiarity and antithrombin binding region profile of mucosal bovine and porcine heparins Fulltext Access 12 Pages 2016
Simultaneous determination of selected tyrosine kinase inhibitors with corticosteroids and antiemetics in rat plasma by solid phase extraction and ultra-performance liquid chromatography–tandem mass spectrometry: Application to pharmacokinetic interaction Fulltext Access 12 Pages 2016
Synthesis, anticancer activity and molecular docking study of Schiff base complexes containing thiazole moiety Fulltext Access 12 Pages 2016
Pickering emulsions based on cyclodextrins: A smart solution for antifungal azole derivatives topical delivery Fulltext Access 12 Pages 2016
Particulate systems based on pectin/chitosan association for the delivery of manuka honey components and platelet lysate in chronic skin ulcers Fulltext Access 12 Pages 2016
The role of helper lipids in the intracellular disposition and transfection efficiency of niosome formulations for gene delivery to retinal pigment epithelial cells Fulltext Access 12 Pages 2016
Bitargeted microemulsions based on coix seed ingredients for enhanced hepatic tumor delivery and synergistic therapy Fulltext Access 12 Pages 2016
Deeper insights into the drug defense of glioma cells against hydrophobic molecules Fulltext Access 12 Pages 2016
Acid-modified montmorillonite for sorption of heavy metals from automobile effluent Fulltext Access 12 Pages 2016
Drug loaded composite oxidized pectin and gelatin networks for accelerated wound healing Fulltext Access 12 Pages 2016
Spray-dried amorphous isomalt and melibiose, two potential protein-stabilizing excipients Fulltext Access 12 Pages 2016
Preparation and evaluation of teniposide-loaded polymeric micelles for breast cancer therapy Fulltext Access 12 Pages 2016
An experimental investigation of temperature rise during compaction of pharmaceutical powders Fulltext Access 12 Pages 2016
Arginine as a protein stabilizer and destabilizer in liquid formulations Fulltext Access 12 Pages 2016
Comparison of the cohesion-adhesion balance approach to colloidal probe atomic force microscopy and the measurement of Hansen partial solubility parameters by inverse gas chromatography for the prediction of dry powder inhalation performance Fulltext Access 12 Pages 2016
Screening of new antileukemic agents from essential oils of algae extracts and computational modeling of their interactions with intracellular signaling nodes Fulltext Access 12 Pages 2016
The potential of immobilized artificial membrane chromatography to predict human oral absorption Fulltext Access 12 Pages 2016
Bioavailability enhancement of atovaquone using hot melt extrusion technology Fulltext Access 12 Pages 2016
Three-dimensional podocyte–endothelial cell co-cultures: Assembly, validation, and application to drug testing and intercellular signaling studies Fulltext Access 12 Pages 2016
A microstructural study of water effects in lipid-based pharmaceutical formulations for liquid filling of capsules Fulltext Access 12 Pages 2016
Spectrophotometric determination of the sulfhydryl containing drug mesna Fulltext Access 12 Pages 2016
Investigation of free amino acid, total phenolics, antioxidant activity and purine alkaloids to assess the health properties of non-Camellia tea Fulltext Access 12 Pages 2016
Mitotic catastrophe and cancer drug resistance: A link that must to be broken Fulltext Access 12 Pages 2016
Effect of roll-compaction and milling conditions on granules and tablet properties Fulltext Access 12 Pages 2016