Part-1: Design, synthesis and biological evaluation of novel bromo-pyrimidine analogs as tyrosine kinase inhibitors Fulltext Access 13 Pages 2016
Strengths, weaknesses, opportunities and challenges for long acting injectable therapies: Insights for applications in HIV therapy Fulltext Access 13 Pages 2016
Uncertainty analysis as essential step in the establishment of the dynamic Design Space of primary drying during freeze-drying Fulltext Access 13 Pages 2016
Large-scale production of human pluripotent stem cell derived cardiomyocytes Fulltext Access 13 Pages 2016
An investigation into the crystallization tendency/kinetics of amorphous active pharmaceutical ingredients: A case study with dipyridamole and cinnarizine Fulltext Access 13 Pages 2016
Development of “all natural” layer-by-layer redispersible solid lipid nanoparticles by nano spray drying technology Fulltext Access 13 Pages 2016
Matricellular proteins in drug delivery: Therapeutic targets, active agents, and therapeutic localization Fulltext Access 13 Pages 2016
A novel liposomal Clodronate depletes tumor-associated macrophages in primary and metastatic melanoma: Anti-angiogenic and anti-tumor effects Fulltext Access 13 Pages 2016
Linking granulation performance with residence time and granulation liquid distributions in twin-screw granulation: An experimental investigation Fulltext Access 13 Pages 2016
Green design “bioinspired disassembly-reassembly strategy” applied for improved tumor-targeted anticancer drug delivery Fulltext Access 13 Pages 2016
Quercetin topical application, from conventional dosage forms to nanodosage forms Fulltext Access 13 Pages 2016
Multi-target screening mines hesperidin as a multi-potent inhibitor: Implication in Alzheimer's disease therapeutics Fulltext Access 13 Pages 2016
Analogue based drug design, synthesis, molecular docking and anticancer evaluation of novel chromene sulfonamide hybrids as aromatase inhibitors and apoptosis enhancers Fulltext Access 13 Pages 2016
Development of a simple, rapid, and robust liquid chromatographic method for the simultaneous determination of sulfalene, sulfadoxine, and pyrimethamine in tablets Fulltext Access 13 Pages 2016
Clinical feasibility of dried blood spots: Analytics, validation, and applications Fulltext Access 13 Pages 2016
Comprehensively priming the tumor microenvironment by cancer-associated fibroblast-targeted liposomes for combined therapy with cancer cell-targeted chemotherapeutic drug delivery system Fulltext Access 13 Pages 2016
Tertiary amine mediated targeted therapy against metastatic lung cancer Fulltext Access 13 Pages 2016
A stabilized peptide ligand for multifunctional glioma targeted drug delivery Fulltext Access 13 Pages 2016
A non-viral suicide gene delivery system traversing the blood brain barrier for non-invasive glioma targeting treatment Fulltext Access 13 Pages 2016
Encapsulation and retention of chelated-copper inside hydrophobic nanoparticles: Liquid cored nanoparticles show better retention than a solid core formulation Fulltext Access 13 Pages 2016
Development of hydroxy-based sphingosine kinase inhibitors and anti-inflammation in dextran sodium sulfate induced colitis in mice Fulltext Access 13 Pages 2016
Synthesis and structure–activity relationships of novel hybrid ferrocenyl compounds based on a bicyclic core skeleton for breast cancer therapy Fulltext Access 13 Pages 2016
Triazole-curcuminoids: A new class of derivatives for ‘tuning’ curcumin bioactivities? Fulltext Access 13 Pages 2016
New hybrid molecules with anticonvulsant and antinociceptive activity derived from 3-methyl- or 3,3-dimethyl-1-[1-oxo-1-(4-phenylpiperazin-1-yl)propan-2-yl]pyrrolidine-2,5-diones Fulltext Access 13 Pages 2016
Design and synthesis of novel androgen receptor antagonists via molecular modeling Fulltext Access 13 Pages 2016
Discovery of novel diaryl urea derivatives bearing a triazole moiety as potential antitumor agents Fulltext Access 13 Pages 2016
Synthesis of triazoloquinazolinone based compounds as tubulin polymerization inhibitors and vascular disrupting agents Fulltext Access 13 Pages 2016
Synthesis, experimental evaluation and molecular modelling of hydroxamate derivatives as zinc metalloproteinase inhibitors Fulltext Access 13 Pages 2016
Design, synthesis, molecular docking and biological evaluation of thiophen-2-iminothiazolidine derivatives for use against Trypanosoma cruzi Fulltext Access 13 Pages 2016
Synthesis and biological evaluation of 2-arylimino-3-pyridin-thiazolineone derivatives as antibacterial agents Fulltext Access 13 Pages 2016
Synthesis and biological evaluation of isomeric methoxy substitutions on anti-cancer indolyl-pyridinyl-propenones: Effects on potency and mode of activity Fulltext Access 13 Pages 2016
Design, synthesis and biological evaluation of novel azaspiro analogs of linezolid as antibacterial and antitubercular agents Fulltext Access 13 Pages 2016
The importance of triazole scaffold in the development of anticonvulsant agents Fulltext Access 13 Pages 2016
Could drugs inhibiting the mevalonate pathway also target cancer stem cells? Fulltext Access 13 Pages 2016
Non-symmetrical furan-amidines as novel leads for the treatment of cancer and malaria Fulltext Access 13 Pages 2016
Selective killing of cancer cells with triterpenoic acid amides - The substantial role of an aromatic moiety alignment Fulltext Access 13 Pages 2016
Sigma receptor-mediated targeted delivery of anti-angiogenic multifunctional nanodrugs for combination tumor therapy Fulltext Access 13 Pages 2016
A novel hybrid drug between two potent anti-tubulin agents as a potential prolonged anticancer approach Fulltext Access 14 Pages 2016
Tailored dendritic core-multishell nanocarriers for efficient dermal drug delivery: A systematic top-down approach from synthesis to preclinical testing Fulltext Access 14 Pages 2016
Optimization of elastic transfersomes formulations for transdermal delivery of pentoxifylline Fulltext Access 14 Pages 2016
The role of tight junctions in skin barrier function and dermal absorption Fulltext Access 14 Pages 2016
Stimuli responsive drug delivery systems based on nano-graphene for cancer therapy Fulltext Access 14 Pages 2016
Self-Assembly of Cyclodextrins and Their Complexes in Aqueous Solutions Fulltext Access 14 Pages 2016
Mechanisms of transport of polymeric and lipidic nanoparticles across the intestinal barrier Fulltext Access 14 Pages 2016
Resolving the physiological conditions in bioavailability and bioequivalence studies: Comparison of fasted and fed state Fulltext Access 14 Pages 2016
Design and synthesis of natural product derivatives with selective and improved cytotoxicity based on a sesquiterpene scaffold Fulltext Access 14 Pages 2016
Effect of hydrogen bond formation/replacement on solubility characteristics, gastric permeation and pharmacokinetics of curcumin by application of powder solution technology Fulltext Access 14 Pages 2016
Pharmacokinetic models of morphine and its metabolites in neonates:: Systematic comparisons of models from the literature, and development of a new meta-model Fulltext Access 14 Pages 2016
Nanostructured lipid carriers of artemether-lumefantrine combination for intravenous therapy of cerebral malaria Fulltext Access 14 Pages 2016
Evaluation of the anti-malarial activity and cytotoxicity of 2,4-diamino-pyrimidine-based kinase inhibitors Fulltext Access 14 Pages 2016
Synthesis, antiamoebic and molecular docking studies of furan-thiazolidinone hybrids Fulltext Access 14 Pages 2016
Aroylhydrazone iron chelators: Tuning antioxidant and antiproliferative properties by hydrazide modifications Fulltext Access 14 Pages 2016
Impact of Ice Morphology on Design Space of Pharmaceutical Freeze-Drying Fulltext Access 14 Pages 2016
Discovery of a sulfamate-based steroid sulfatase inhibitor with intrinsic selective estrogen receptor modulator properties Fulltext Access 14 Pages 2016
Design and synthesis of novel bicalutamide and enzalutamide derivatives as antiproliferative agents for the treatment of prostate cancer Fulltext Access 14 Pages 2016
Self-assembling peptide-based delivery of therapeutics for myocardial infarction Fulltext Access 14 Pages 2016
Advanced formulations for improving therapies with anti-inflammatory or anaesthetic drugs: A review Fulltext Access 14 Pages 2016
Laminated sponges as challenging solid hydrophilic matrices for the buccal delivery of carvedilol microemulsion systems: Development and proof of concept via mucoadhesion and pharmacokinetic assessments in healthy human volunteers Fulltext Access 14 Pages 2016
Factors to consider in developing individual pharmaceutical product quality risk profiles useful to government procurement agencies Fulltext Access 14 Pages 2016
Structural optimization and biological evaluation of 1,5-disubstituted pyrazole-3-carboxamines as potent inhibitors of human 5-lipoxygenase Fulltext Access 14 Pages 2016
Renew or die: The molecular mechanisms of peptidoglycan recycling and antibiotic resistance in Gram-negative pathogens Fulltext Access 14 Pages 2016
A novel floating controlled release drug delivery system prepared by hot-melt extrusion Fulltext Access 14 Pages 2016
Optimization of the bake-on siliconization of cartridges. Part II: Investigations into burn-in time and temperature Fulltext Access 14 Pages 2016
Continuous melt granulation: Influence of process and formulation parameters upon granule and tablet properties Fulltext Access 14 Pages 2016
Integrated Application of Quality-by-Design Principles to Drug Product Development: A Case Study of Brivanib Alaninate Film-Coated Tablets Fulltext Access 14 Pages 2016
Increased local delivery of antagomir therapeutics to the rodent myocardium using ultrasound and microbubbles Fulltext Access 14 Pages 2016
The effect of macrophage and angiogenesis inhibition on the drug release and absorption from an intramuscular sustained-release paliperidone palmitate suspension Fulltext Access 14 Pages 2016
Synthesis, pharmacological assessment, molecular modeling and in silico studies of fused tricyclic coumarin derivatives as a new family of multifunctional anti-Alzheimer agents Fulltext Access 14 Pages 2016
Design, synthesis, and biological evaluation of novel quinazolinyl-diaryl urea derivatives as potential anticancer agents Fulltext Access 14 Pages 2016
Design, synthesis and biological evaluation of chalconyl blended triazole allied organosilatranes as giardicidal and trichomonacidal agents Fulltext Access 14 Pages 2016
Surface decorated nanoparticles as surrogate carriers for improved transport and absorption of epirubicin across the gastrointestinal tract: Pharmacokinetic and pharmacodynamic investigations Fulltext Access 14 Pages 2016
Tacrolimus and curcumin co-loaded liposphere gel: Synergistic combination towards management of psoriasis Fulltext Access 14 Pages 2016
Anticancer drug-loaded hydrogels as drug delivery systems for the local treatment of glioblastoma Fulltext Access 14 Pages 2016
Delivery of drugs and macromolecules to the mitochondria for cancer therapy Fulltext Access 14 Pages 2016
Nanomaterial-based sensors for detection of foodborne bacterial pathogens and toxins as well as pork adulteration in meat products Fulltext Access 14 Pages 2016
Development of prilling process for biodegradable microspheres through experimental designs Fulltext Access 14 Pages 2016
Non-invasive epicutaneous vaccine against Respiratory Syncytial Virus: Preclinical proof of concept Fulltext Access 14 Pages 2016
Novel galactosylated biodegradable nanoparticles for hepatocyte-delivery of oridonin Fulltext Access 14 Pages 2016
Optimisation of vectorisation property: A comparative study for a secondary amphipathic peptide Fulltext Access 14 Pages 2016
Electrostatic powder coating: Principles and pharmaceutical applications Fulltext Access 14 Pages 2016
Experimental and computational determination of the hydrodynamics of mini vessel dissolution testing systems Fulltext Access 14 Pages 2016
The use of rheology to elucidate the granulation mechanisms of a miscible and immiscible system during continuous twin-screw melt granulation Fulltext Access 14 Pages 2016
Novel chitin/chitosan-glucan wound dressing: Isolation, characterization, antibacterial activity and wound healing properties Fulltext Access 14 Pages 2016
Near infrared spectroscopic calibration models for real time monitoring of powder density Fulltext Access 14 Pages 2016
Bioactive compounds isolated from apple, tea, and ginger protect against dicarbonyl induced stress in cultured human retinal epithelial cells Fulltext Access 14 Pages 2016