The development of stroke therapeutics: Promising mechanisms and translational challenges Fulltext Access 13 Pages 2009
Regulation of genistein-induced differentiation in human acute myeloid leukaemia cells (HL60, NB4): Protein kinase modulation and reactive oxygen species generation Fulltext Access 13 Pages 2009
Safeguarding against substandard/counterfeit drugs: Mitigating a macroeconomic pandemic Fulltext Access 13 Pages 2009
The effect of an educational intervention on patients' knowledge about hypertension, beliefs about medicines, and adherence Fulltext Access 13 Pages 2009
Pharmacists' communication with Spanish-speaking patients: A review of the literature to establish an agenda for future research Fulltext Access 13 Pages 2009
Suspected hepatotoxicity by Cimicifugae racemosae rhizoma (black cohosh, root): Critical analysis and structured causality assessment Fulltext Access 13 Pages 2009
Protective activity of plicatin B against human LDL oxidation induced in metal ion-dependent and -independent processes. Experimental and theoretical studies Fulltext Access 13 Pages 2009
Towards a quantitative representation of the cell signaling mechanisms of hallucinogens: Measurement and mathematical modeling of 5-HT1A and 5-HT2A receptor-mediated ERK1/2 activation Fulltext Access 13 Pages 2009
Methylphenidate normalises activation and functional connectivity deficits in attention and motivation networks in medication-naïve children with ADHD during a rewarded continuous performance task Fulltext Access 13 Pages 2009
Expression levels of the α4 subunit of the GABAA receptor in differentiated neuroblastoma cells are correlated with GABA-gated current Fulltext Access 13 Pages 2009
Effects of dexamethasone, administered for growth promoting purposes, upon the hepatic cytochrome P450 3A expression in the veal calf Fulltext Access 13 Pages 2009
Factors that restrict intestinal cell permeation of cyclic prodrugs of an opioid peptide (DADLE): Part II. Role of metabolic enzymes in the intestinal mucosa Fulltext Access 13 Pages 2009
Controlled release of Repifermin® from polyelectrolyte complexes stimulates endothelial cell proliferation Fulltext Access 13 Pages 2009
Solid State Characterization and Crystal Structure from X-ray Powder Diffraction of Two Polymorphic Forms of Ranitidine Base Fulltext Access 13 Pages 2009
The Glass Transition and Sub-Tg-Relaxation in Pharmaceutical Powders and Dried Proteins by Thermally Stimulated Current Fulltext Access 13 Pages 2009
Common Excipients Impair Detection of Protein Aggregates During Sedimentation Velocity Analytical Ultracentrifugation Fulltext Access 13 Pages 2009
Peptide Derivation of Poorly Absorbable Drug Allows Intestinal Absorption Via Peptide Transporter Fulltext Access 13 Pages 2009
Characterization and Optimization of AMG 517 Supersaturatable SelfâEmulsifying Drug Delivery System (SâSEDDS) for Improved Oral Absorption Fulltext Access 13 Pages 2009
Dry Powder Formulations for Inhalation of Fluticasone Propionate and Salmeterol Xinafoate Microcrystals Fulltext Access 13 Pages 2009
Porcine Buccal Mucosa as an In Vitro Model: Relative Contribution of Epithelium and Connective Tissue as Permeability Barriers Fulltext Access 13 Pages 2009
Why pesticides could be a common cause of prostate and breast cancers in the French Caribbean Island, Martinique. An overview on key mechanisms of pesticide-induced cancer Fulltext Access 13 Pages 2009
Differential regulation of TRP channels in a rat model of neuropathic pain Fulltext Access 13 Pages 2009
Treatment of fibromyalgia syndrome with gabapentin and pregabalin - A meta-analysis of randomized controlled trials Fulltext Access 13 Pages 2009
Cromoglycate drugs suppress eicosanoid generation in U937 cells by promoting the release of Anx-A1 Fulltext Access 13 Pages 2009
Context-dependent modulation of αβγ and αβδ GABAA receptors by penicillin: Implications for phasic and tonic inhibition Fulltext Access 13 Pages 2009
Dioxin activation of CYP1A5 promoter/enhancer regions from two avian species, common cormorant (Phalacrocorax carbo) and chicken (Gallus gallus): Association with aryl hydrocarbon receptor 1 and 2 isoforms Fulltext Access 13 Pages 2009
Development of quantitative structure–activity relationship (QSAR) models to predict the carcinogenic potency of chemicals: I. Alternative toxicity measures as an estimator of carcinogenic potency Fulltext Access 13 Pages 2009
Inhibition of both COX-1 and COX-2 and resulting decrease in the level of prostaglandins E2 is responsible for non-steroidal anti-inflammatory drug (NSAID)-dependent exacerbation of colitis Fulltext Access 13 Pages 2009
Targeting the endoplasmic reticulum-stress response as an anticancer strategy Fulltext Access 13 Pages 2009
Spinal astrocyte and microglial activation contributes to rat pain-related behaviors induced by the venom of scorpion Buthus martensi Karch Fulltext Access 13 Pages 2009
The thiazolidinediones rosiglitazone and pioglitazone and the risk of coronary heart disease: A retrospective cohort study using a US health insurance database Fulltext Access 13 Pages 2009
Results of a retrospective claims database analysis of differences in antidepressant treatment persistence associated with escitalopram and other selective serotonin reuptake inhibitors in the United States Fulltext Access 13 Pages 2009
Besifloxacin ophthalmic suspension 0.6% in patients with bacterial conjunctivitis: A multicenter, prospective, randomized, double-masked, vehicle-controlled, 5-day efficacy and safety study Fulltext Access 13 Pages 2009
Physiological Models Are Good Tools to Predict Rat Bioavailability of EF5154 Prodrugs from In Vitro Intestinal Parameters Fulltext Access 13 Pages 2009
Expression and transcriptional regulation of ABC transporters and cytochromes P450 in hCMEC/D3 human cerebral microvascular endothelial cells Fulltext Access 13 Pages 2009
Teupolioside, a phenylpropanoid glycosides of Ajuga reptans, biotechnologically produced by IRBN22 plant cell line, exerts beneficial effects on a rodent model of colitis Fulltext Access 13 Pages 2009
Inhibiting the function of ABCB1 and ABCG2 by the EGFR tyrosine kinase inhibitor AG1478 Fulltext Access 13 Pages 2009
Mechanisms underlying the nociceptive responses induced by platelet-activating factor (PAF) in the rat paw Fulltext Access 13 Pages 2009
Dissection of the inhibition of cardiac ryanodine receptors by human glutathione transferase GSTM2-2 Fulltext Access 13 Pages 2009
In vitro studies on the metabolism of trabectedin (YONDELIS®) in monkey and man, including human CYP reaction phenotyping Fulltext Access 13 Pages 2009
Fitting a xenobiotic receptor into cell homeostasis: How the dioxin receptor interacts with TGFβ signaling Fulltext Access 13 Pages 2009
The role of the aryl hydrocarbon receptor in the female reproductive system Fulltext Access 13 Pages 2009
Growth factors, cytokines and their receptors as downstream targets of arylhydrocarbon receptor (AhR) signaling pathways Fulltext Access 13 Pages 2009
Regulation of constitutive and inducible AHR signaling: Complex interactions involving the AHR repressor Fulltext Access 13 Pages 2009
Characterization of the naturally occurring Arg344His variant of the human 5-HT3A receptor Fulltext Access 13 Pages 2009
Development and Evaluation of Perfluorocarbon Nanobubbles for Apomorphine Delivery Fulltext Access 13 Pages 2009
The Role of Covalent Dimerization on the Physical and Chemical Stability of the EC1 Domain of Human E-Cadherin Fulltext Access 13 Pages 2009
Succinimide formation at Asn 55 in the complementarity determining region of a recombinant monoclonal antibody IgG1 heavy chain Fulltext Access 13 Pages 2009
A screening study of surface stabilization during the production of drug nanocrystals Fulltext Access 13 Pages 2009
Preparation, physiochemical characterization, and oral immunogenicity of Aβ(1-12), Aβ(29-40), and Aβ(1-42) loaded PLG microparticles formulations Fulltext Access 13 Pages 2009
Les cytokines du système immunitaire et leurs antagonistes en thérapeutique Fulltext Access 13 Pages 2009
Metabotropic glutamate receptors in the tripartite synapse as a target for new psychotropic drugs Fulltext Access 13 Pages 2009
Mitochondrial dysfunction in nonalcoholic steatohepatitis (NASH): are there drugs able to improve it? Fulltext Access 13 Pages 2009
From osteoarthritis treatments to future regenerative therapies for cartilage Fulltext Access 13 Pages 2009
Micro- and nanofluidic systems for high-throughput biological screening Fulltext Access 13 Pages 2009
Neurobiology of the development of motivated behaviors in adolescence: A window into a neural systems model Fulltext Access 13 Pages 2009
On the Mechanism and Dynamics of Uptake and Permeation of Polyether-Copolyester Dendrimers Across an In Vitro Blood-Brain Barrier Model Fulltext Access 13 Pages 2009
Anti-diabetic effects of 1-methylnicotinamide (MNA) in streptozocin-induced diabetes in rats Fulltext Access 13 Pages 2009
Contaminant effects in shore crabs (Carcinus maenas) from Ria Formosa Lagoon Fulltext Access 13 Pages 2009
Repeated risperidone treatment increases the expression of NCAM and PSA-NCAM protein in the rat medial prefrontal cortex Fulltext Access 13 Pages 2009
BL-1020: A novel antipsychotic drug with GABAergic activity and low catalepsy, is efficacious in a rat model of schizophrenia Fulltext Access 13 Pages 2009
Advantages and disadvantages of combination treatment with antipsychotics: ECNP Consensus Meeting, March 2008, Nice Fulltext Access 13 Pages 2009
Alprazolam treatment immediately after stress exposure interferes with the normal HPA-stress response and increases vulnerability to subsequent stress in an animal model of PTSD Fulltext Access 13 Pages 2009
Atomoxetine hydrochloride in the treatment of children and adolescents with attention-deficit/hyperactivity disorder and comorbid oppositional defiant disorder: A placebo-controlled Italian study Fulltext Access 13 Pages 2009
Chronic fluoxetine differentially modulates the hippocampal microtubular and serotonergic system in grouped and isolation reared rats Fulltext Access 13 Pages 2009
No clinically relevant pharmacokinetic and safety interactions of ambrisentan in combination with tadalafil in healthy volunteers Fulltext Access 13 Pages 2009
Sprayâdried carrierâfree dry powder tobramycin formulations with improved dispersion properties Fulltext Access 13 Pages 2009
Solid state chemistry of proteins IV. what is the meaning of thermal denaturation in freeze dried proteins? Fulltext Access 13 Pages 2009
Docetaxel-Albumin Conjugates: Preparation, In Vitro Evaluation and Biodistribution Studies Fulltext Access 13 Pages 2009
Informatic Calibration of a Materials Properties Database for Predictive Assessment of Mechanically Activated Disordering Potential for Small Molecule Organic Solids Fulltext Access 13 Pages 2009
Fabrication via a nonaqueous nanoprecipitation method, characterization and in vitro biological behavior of N6-cyclopentyladenosine-loaded nanoparticles Fulltext Access 13 Pages 2009
A pharmacoscintigraphic study of three time-delayed capsule formulations in healthy male volunteers Fulltext Access 13 Pages 2009
Differences in the interaction between aryl propionic acid derivatives and poly(vinylpyrrolidone) K30: A multi-methodological approach Fulltext Access 13 Pages 2009
Amorphous Drug-PVP Dispersions: Application of Theoretical, Thermal and Spectroscopic Analytical Techniques to the Study of a Molecule With Intermolecular Bonds in Both the Crystalline and Pure Amorphous State Fulltext Access 13 Pages 2009
Non-Invasive Product Temperature Determination during Primary Drying using Tunable Diode Laser Absorption Spectroscopy Fulltext Access 13 Pages 2009
Effects of Micelles and Vesicles on the Oximolysis of pâNitrophenyl Diphenyl Phosphate: A Model System for SurfactantâBased SkinâDefensive Formulations against Organophosphates Fulltext Access 13 Pages 2009
Influence of Storage Relative Humidity on the Dispersion of Salmeterol Xinafoate Powders for Inhalation Fulltext Access 13 Pages 2009
A distinct pattern of intracellular glucocorticoid-related responses is associated with extreme behavioral response to stress in an animal model of post-traumatic stress disorder Fulltext Access 13 Pages 2009
Differential Involvement of P-Glycoprotein (ABCB1) in Permeability, Tissue Distribution, and Antinociceptive Activity of Methadone, Buprenorphine, and Diprenorphine: In Vitro and In Vivo Evaluation Fulltext Access 13 Pages 2009
Paracetamol-loaded poly(ε-caprolactone) layered silicate nanocomposites prepared using hot-melt extrusion Fulltext Access 13 Pages 2009
The role of mucoadhesion of trimethyl chitosan and PEGylated trimethyl chitosan nanocomplexes in insulin uptake Fulltext Access 13 Pages 2009
A new natural angelica polysaccharide based colon-specific drug delivery system Fulltext Access 13 Pages 2009
Miscibility/stability considerations in binary solid dispersion systems composed of functional excipients towards the design of multi-component amorphous systems Fulltext Access 13 Pages 2009
Glycosylation of aromatic amines II: Kinetics and mechanisms of the hydrolytic reaction between kynurenine and glucose Fulltext Access 13 Pages 2009
Multivariate modeling of encapsulation and release of an ionizable drug from polymer microspheres Fulltext Access 13 Pages 2009
The effect of experimental hyperlipidemia on the stereoselective tissue distribution, lipoprotein association and microsomal metabolism of (±)-halofantrine Fulltext Access 13 Pages 2009
Preparation and characterization of negatively charged poly(lactic-co-glycolic acid) microspheres Fulltext Access 13 Pages 2009
Synthesis, hydrolysis, and skin retention of amino acid esters of α-tocopherol Fulltext Access 13 Pages 2009
Influence of Plasma Protein Binding on Pharmacodynamics: Estimation of In Vivo Receptor Affinities of β Blockers Using a New Mechanism-Based PK-PD Modelling Approach Fulltext Access 13 Pages 2009