Effect of the pyrrolopyrimidine lipid peroxidation inhibitor U-101033E on neuronal and astrocytic metabolism and infarct volume in rats with transient middle cerebral artery occlusion Fulltext Access 9 Pages 2007
Inhibition of cystathionine-γ-lyase leads to loss of glutathione and aggravation of mitochondrial dysfunction mediated by excitatory amino acid in the CNS Fulltext Access 9 Pages 2007
Differential regulation of calcium channel coding genes by prolonged depolarization Fulltext Access 9 Pages 2007
Metabolic changes in rat prefrontal cortex and hippocampus induced by chronic morphine treatment studied ex vivo by high resolution 1H NMR spectroscopy Fulltext Access 9 Pages 2007
Effects of melatonin and age on gene expression in mouse CNS using microarray analysis Fulltext Access 9 Pages 2007
Treatment of hypoxic–ischemic encephalopathy in mouse by transplantation of embryonic stem cell-derived cells Fulltext Access 9 Pages 2007
Inhibition of p38 mitogen-activated protein kinase-induced apoptosis in cultured mature oligodendrocytes using SB202190 and SB203580 Fulltext Access 9 Pages 2007
Toxicity of β-amyloid in HEK293 cells expressing NR1/NR2A or NR1/NR2B N-methyl-d-aspartate receptor subunits Fulltext Access 9 Pages 2007
Dextromethorphan attenuates trimethyltin-induced neurotoxicity via σ1 receptor activation in rats Fulltext Access 9 Pages 2007
Upregulation of dihydropyrimidinase-related protein 2, spectrin α II chain, heat shock cognate protein 70 pseudogene 1 and tropomodulin 2 after focal cerebral ischemia in rats—A proteomics approach Fulltext Access 9 Pages 2007
Mitogen activated protein kinase and protein kinase C activation mediate promotion of sAPPα secretion by deprenyl Fulltext Access 9 Pages 2007
The new 2,3-benzodiazepine derivative EGIS-8332 inhibits AMPA/kainate ion channels and cell death Fulltext Access 9 Pages 2007
Butyrylcholinesterase activity and molecular components in thymus of healthy and merosin-deficient Lama2dy mice Fulltext Access 9 Pages 2007
Pre- and postsynaptic mechanisms in the clonidine- and oxymetazoline-induced inhibition of gastric motility in the rat Fulltext Access 9 Pages 2007
S100B content and secretion decrease in astrocytes cultured in high-glucose medium Fulltext Access 9 Pages 2007
The role of c-AMP-dependent protein kinase in spinal cord and post synaptic dorsal column neurons in a rat model of visceral pain Fulltext Access 9 Pages 2007
Geniposide, a novel agonist for GLP-1 receptor, prevents PC12 cells from oxidative damage via MAP kinase pathway Fulltext Access 9 Pages 2007
Activator protein-1 responsive to the group II metabotropic glutamate receptor subtype in association with intracellular calcium in cultured rat cortical neurons Fulltext Access 9 Pages 2007
Estrogen modulates potassium currents and expression of the Kv4.2 subunit in GT1-7 cells Fulltext Access 9 Pages 2007
Inhibition of neuronal nitric oxide synthase causes attenuation of cerebrovascular dysfunction in experimental heatstroke Fulltext Access 9 Pages 2007
Characterisation of the human NMDA receptor subunit NR3A glycine binding site Fulltext Access 9 Pages 2007
Repeated treatment with cannabidiol but not Δ9-tetrahydrocannabinol has a neuroprotective effect without the development of tolerance Fulltext Access 9 Pages 2007
Cannabinoid modulation of neuronal function after oxygen/glucose deprivation in area CA1 of the rat hippocampus Fulltext Access 9 Pages 2007
Region specific galanin receptor/neuropeptide Y Y1 receptor interactions in the tel- and diencephalon of the rat. Relevance for food consumption Fulltext Access 9 Pages 2007
Strain and schedule-dependent differences in the acquisition, maintenance and extinction of intravenous cannabinoid self-administration in rats Fulltext Access 9 Pages 2007
CB1 cannabinoid receptors inhibit the glutamatergic component of KCl-evoked excitation of locus coeruleus neurons in rat brain slices Fulltext Access 9 Pages 2007
Pre-synaptic histamine H3 receptors regulate glutamate, but not GABA release in rat thalamus Fulltext Access 9 Pages 2007
Activation of sensory neurons contributes to reduce spinal cord injury in rats Fulltext Access 9 Pages 2007
A single point mutation of the GABAA receptor α5-subunit confers fluoxetine sensitivity Fulltext Access 9 Pages 2007
Benzodiazepine inhibits hypothalamic presympathetic neurons by potentiation of GABAergic synaptic input Fulltext Access 9 Pages 2007
The mGlu1 antagonist CPCCOEt enhances the climbing fibre response in Purkinje neurones independently of glutamate receptors Fulltext Access 9 Pages 2007
A nerve growth factor-induced retrograde survival signal mediated by mechanisms downstream of TrkA Fulltext Access 9 Pages 2007
Carbamazepine prevents breakdown of neurotransmitter release induced by hyperactivation of ryanodine receptor Fulltext Access 9 Pages 2007
D2-like receptors in nucleus accumbens negatively modulate acetylcholine release in prefrontal cortex Fulltext Access 9 Pages 2007
Inhibition of hyperpolarization-activated cation currents by phencyclidine and some sigma ligands in rat hippocampal CA1 pyramidal neurons in vitro Fulltext Access 9 Pages 2007
Frontal cortical α7 and α4β2 nicotinic acetylcholine receptors in working and reference memory Fulltext Access 9 Pages 2007
Anti-apoptotic effect of esculin on dopamine-induced cytotoxicity in the human neuroblastoma SH-SY5Y cell line Fulltext Access 9 Pages 2007
Expérimentations de coopération et de délégation de tâches entre professions de santé Fulltext Access 9 Pages 2007
The serine protease Omi/HtrA2 is involved in XIAP cleavage and in neuronal cell death following focal cerebral ischemia/reperfusion Fulltext Access 9 Pages 2007
The effect of bovine serum albumin on the membrane potential and reactive oxygen species generation in succinate-supported isolated brain mitochondria Fulltext Access 9 Pages 2007
CCK-8 induces NGF and BDNF synthesis and modulates TrkA and TrkB expression in the rat hippocampus and septum: Effects on kindling development Fulltext Access 9 Pages 2007
Clozapine treatment reverses dizocilpine-induced deficits of pre-pulse inhibition of tactile startle response Fulltext Access 9 Pages 2007
Ethanol sensitization in a neurodevelopmental lesion model of Schizophrenia in rats Fulltext Access 9 Pages 2007
MK-801 infusions to the ventral tegmental area and ventromedial hypothalamus produce opposite effects on lordosis of hormone-primed rats Fulltext Access 9 Pages 2007
A randomized clinical trial of a targeted intervention to moderate alcohol use and alcohol-related problems in at-risk adolescents Fulltext Access 9 Pages 2007
Age, sex and early environment contribute to individual differences in nicotine/acetaldehyde-induced behavioral and endocrine responses in rats Fulltext Access 9 Pages 2007
Adaptive plasticity of NMDA receptors and dendritic spines: Implications for enhanced vulnerability of the adolescent brain to alcohol addiction Fulltext Access 9 Pages 2007
An MR-compatible device for delivering smoked marijuana during functional imaging Fulltext Access 9 Pages 2007
Effects of SKF-38393, a dopamine D1 receptor agonist on expression of amphetamine-induced behavioral sensitization and expression of immediate early gene arc in prefrontal cortex of rats Fulltext Access 9 Pages 2007
Oral administration of (±)3,4-methylenedioxymethamphetamine and (+)methamphetamine alters temperature and activity in rhesus macaques Fulltext Access 9 Pages 2007
Chronic nicotine administration improves attention while nicotine withdrawal induces performance deficits in the 5-choice serial reaction time task in rats Fulltext Access 9 Pages 2007
The partial 5-HT1A agonist buspirone reduces the expression and development of l-DOPA-induced dyskinesia in rats and improves l-DOPA efficacy Fulltext Access 9 Pages 2007
Chronic ethanol intake modulates photic and non-photic circadian phase responses in the Syrian hamster Fulltext Access 9 Pages 2007
Bupropion dose-dependently reverses nicotine withdrawal deficits in contextual fear conditioning Fulltext Access 9 Pages 2007
DNA fragmentation based combinatorial approaches to soluble protein expression: Part II: Library expression, screening and scale-up Fulltext Access 9 Pages 2007
Role of dopamine D1 and D2 receptors in CRF-induced disruption of sensorimotor gating Fulltext Access 9 Pages 2007
Depression and poor sleep: The effect of monoaminergic antidepressants in a pre-clinical model in rats Fulltext Access 9 Pages 2007
Behavioral sensitization produced by a single administration of apomorphine: Implications for the role of Pavlovian conditioning in the mediation of context-specific sensitization Fulltext Access 9 Pages 2007
Further evidence that the delayed temporal dopaminergic effects of LSD are mediated by a mechanism different than the first temporal phase of action Fulltext Access 9 Pages 2007
Operant leverpressing and wheelrunning were differentially reduced by PAPP (p-aminopropiophenone)-induced methemoglobinemia Fulltext Access 9 Pages 2007
Dependence-induced increases in ethanol self-administration in mice are blocked by the CRF1 receptor antagonist antalarmin and by CRF1 receptor knockout Fulltext Access 9 Pages 2007
Gugulipid, an extract of Commiphora whighitii with lipid-lowering properties, has protective effects against streptozotocin-induced memory deficits in mice Fulltext Access 9 Pages 2007
Individual differences in novelty- and cocaine-induced locomotor activity as predictors of food-reinforced operant behavior in two outbred rat strains Fulltext Access 9 Pages 2007
The dopamine D3 receptor antagonist NGB 2904 increases spontaneous and amphetamine-stimulated locomotion Fulltext Access 9 Pages 2007
Pharmaceutical R&D in the spotlight: why is there still unmet medical need? Fulltext Access 9 Pages 2007
Co-stimulatory molecules as therapeutic targets in allergic airways disease Fulltext Access 9 Pages 2007
Membrane rafts in endothelial cells and their modulation by proatherogenic stimuli Fulltext Access 9 Pages 2007
Huntington's and other polyglutamine diseases: many effects of single gene mutations Fulltext Access 9 Pages 2007
Multi-target therapeutics: when the whole is greater than the sum of the parts Fulltext Access 9 Pages 2007
Effects of interleukin-1β and lipopolysaccharide on behavior of mice in the elevated plus-maze and open field tests Fulltext Access 9 Pages 2007
Computational systems biology in drug discovery and development: methods and applications Fulltext Access 9 Pages 2007
Pharmacological modulation of the leukotriene pathway in allergic airway disease Fulltext Access 9 Pages 2007
PTP1B as a drug target: recent developments in PTP1B inhibitor discovery Fulltext Access 9 Pages 2007
Molecular similarity analysis in virtual screening: foundations, limitations and novel approaches Fulltext Access 9 Pages 2007
PDE inhibitors in psychiatry – future options for dementia, depression and schizophrenia? Fulltext Access 9 Pages 2007
Improving the drug selection and development process for combination devices Fulltext Access 9 Pages 2007