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Pharmacology Research Articles

An inhibitory effect of A20 on NF-κB activation in airway epithelium upon influenza virus infection
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Receptors involved in moxonidine-stimulated atrial natriuretic peptide release from isolated normotensive rat hearts
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Anticonvulsant effect of the selective 5-HT1B receptor agonist CP 94253 in mice
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Characterization of cytotoxic actions of tricyclic antidepressants on human HT29 colon carcinoma cells
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Tubular transporters and clearance of adefovir
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α1L-Adrenoceptors mediate contractions of the isolated mouse prostate
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Attenuation of morphine tolerance and dependence by aminoguanidine in mice
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Effects of quinones and flavonoids on the reduction of all-trans retinal to all-trans retinol in pig heart
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Sildenafil reduces cardiovascular remodeling associated with hypertensive cardiomyopathy in NOS inhibitor-treated rats
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Gomisin A improves scopolamine-induced memory impairment in mice
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Protections of pinocembrin on brain mitochondria contribute to cognitive improvement in chronic cerebral hypoperfused rats
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(−)-Trans-ε-viniferin, a polyphenol present in wines, is an inhibitor of noradrenaline and 5-hydroxytryptamine uptake and of monoamine oxidase activity
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Tanshinone IIA inhibits LPS-induced NF-κB activation in RAW 264.7 cells: Possible involvement of the NIK–IKK, ERK1/2, p38 and JNK pathways
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Effect of inhibition of nitric oxide synthase on renal cyclooxygenase in the diabetic rat
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The protective effect of nitroglycerin on gastrointestinal and renal side effects of lornoxicam in rats
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Mechanisms of direct relaxant effect of sildenafil, tadalafil and vardenafil on corpus cavernosum
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2-Aminoethoxydiphenyl borate inhibits KCl-induced vascular smooth muscle contraction
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Reactive oxygen species mediate phorbol ester-stimulated cAMP response in human eosinophils
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Effects of N-acetylcysteine on sucrose-rich diet-induced hyperglycaemia, dyslipidemia and oxidative stress in rats
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Mechanism of hypolipidemic effect of crocin in rats: Crocin inhibits pancreatic lipase
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Effect of YM598, a selective endothelin ETA receptor antagonist, on endothelin-1-induced bone formation
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Distinct mono- and dinucleotide-specific P2Y receptors in A549 lung epithelial cells: Different control of arachidonic acid release and nitric oxide synthase expression
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Antiinflammatory and antiallodynic actions of the lignan niranthin isolated from Phyllanthus amarus: Evidence for interaction with platelet activating factor receptor
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Differential expression of α1-adrenergic receptor subtypes in coronary microvascular endothelial cells in culture
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EDHF-mediated rapid restoration of hypotensive response to acetylcholine after chronic, but not acute, nitric oxide synthase inhibition in rats
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Dexamethasone increases fluid absorption via Na+/H+ exchanger (NHE) 3 activation in normal human middle ear epithelial cells
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Protective effect of naproxen (non-selective COX-inhibitor) or rofecoxib (selective COX-2 inhibitor) on immobilization stress-induced behavioral and biochemical alterations in mice
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Characterization of the antinociceptive effects of oxycodone in diabetic mice
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Keyword index
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The effect of mGlu5 receptor positive allosteric modulators on signaling molecules in brain slices
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Effects of drugs acting on the GABA-benzodiazepine receptor complex on flurothyl-induced seizures in Mongolian gerbils
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Blockade of cannabinoid CB1 receptors alters contextual learning and memory
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Inhibition of in vivo angiogenesis by N-β-alanyl-5-S-glutathionyl-3,4-dihydroxyphenylalanine
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Anti-tumor necrosis factor agent PEG-sTNFRI improves the growth hormone/insulin-like growth factor-I system in adjuvant-induced arthritic rats
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Binding characteristics of levetiracetam to synaptic vesicle protein 2A (SV2A) in human brain and in CHO cells expressing the human recombinant protein
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Indapamide induces apoptosis of GH3 pituitary cells independently of its inhibition of voltage-dependent K+ currents
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Identification of a novel regulatory mechanism for norepinephrine transporter activity by the IP3 receptor
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Secretory phospholipase A2 induces apoptosis through TNF-α and cytochrome c-mediated caspase cascade in murine macrophage RAW 264.7 cells
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Estrogen modulates in vitro atrial bradycardia induced by Indian red scorpion venom via G-protein coupled mechanisms
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Cardamonin, inhibits pro-inflammatory mediators in activated RAW 264.7 cells and whole blood
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Mast cell chymase induces expression of chemokines for neutrophils in eosinophilic EoL-1 cells and mouse peritonitis eosinophils
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An orally active reversible inhibitor of cathepsin S inhibits human trans vivo delayed-type hypersensitivity
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Epithelial cell proliferation is promoted by the histamine H3 receptor agonist (R)-α-methylhistamine throughout the rat gastrointestinal tract
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Superoxide auto-augments superoxide formation and upregulates gp91phox expression in porcine pulmonary artery endothelial cells: Inhibition by iloprost
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The in vivo effect of adrenomedullin on rat dural and pial arteries
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Topographical resolution of jaw movements mediated by cyclase- vs. non-cyclase-coupled dopamine D1-like receptors: Studies with SK&F 83822
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Protective effect of protocatechuic acid from Alpinia oxyphylla on hydrogen peroxide-induced oxidative PC12 cell death
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Suppression of interleukin-6 by minocycline in a rat model of neuropathic pain
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Effects of YM218, a nonpeptide vasopressin V1A receptor-selective antagonist, on vasopressin-induced growth responses in human mesangial cells
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Effects of (−)-epigallocatechin-3-gallate on pancreatic beta-cell damage in streptozotocin-induced diabetic rats
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A Rho-kinase inhibitor, Y-27632, reduces cholinergic contraction but not neurotransmitter release
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Effects of postconditioning of adenosine and acetylcholine on the ischemic isolated rat ventricular myocytes
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Intermedin1–53 protects the heart against isoproterenol-induced ischemic injury in rats
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Anti-arrhythmic and cardio-protective effects of furnidipine in a rat model: A dose response study
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Differential effects of methamphetamine and cocaine on behavior and extracellular levels of dopamine and 3,4-dihydroxyphenylalanine in the nucleus accumbens of conscious rats
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Effect of levofloxacin on serum glucose concentration in rats
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Anti-hyperlipidemic properties of CM108 (a flavone derivative) in vitro and in vivo
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N-tosyl-l-phenylalanyl-chloromethyl ketone reduces ceramide during hypoxic–ischemic brain injury in newborn rat
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Imatinib mesylate (Gleevec®) enhances mature osteoclast apoptosis and suppresses osteoclast bone resorbing activity
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Puerarin, an isoflavonoid derived from Radix puerariae, potentiates endothelium-independent relaxation via the cyclic AMP pathway in porcine coronary artery
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The motor-impairing effects of GABAA and GABAB agonists in γ-hydroxybutyrate (GHB)-treated rats: Cross-tolerance to baclofen but not flunitrazepam
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Ginsenoside Re of Panax ginseng possesses significant antioxidant and antihyperlipidemic efficacies in streptozotocin-induced diabetic rats
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Pharmacological profile of a novel phosphodiesterase 7A and -4 dual inhibitor, YM-393059, on acute and chronic inflammation models
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Cryptotanshinone inhibits cyclooxygenase-2 enzyme activity but not its expression
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Oral administration of nicorandil enhances the survival of ischemic skin flaps in rats
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Effects of genetic background and null mutation of 5-HT1A receptors on basal and stress-induced body temperature: Modulation by serotonergic and GABAA-ergic drugs
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Antinociceptive action of (±)-cis-(6-ethyl-tetrahydropyran-2-yl)-formic acid in mice
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Effects of peripheral-type benzodiazepine receptor ligands on Ehrlich tumor cell proliferation
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Oxidized ATP decreases β-actin expression and intracellular superoxide concentrations in RBA-2 type-2 astrocytes independently of P2X7 receptor
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Inhibition of phosphorylation of p38 MAPK involved in the protection of nephropathy by emodin in diabetic rats
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Apelin increases contractility in failing cardiac muscle
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The proarrhythmic antihistaminic drug terfenadine increases spontaneous calcium release in human atrial myocytes
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Pregabalin action at a model synapse: Binding to presynaptic calcium channel α2-δ subunit reduces neurotransmission in mice
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Effect of norepinephrine on RhoA, MAP kinase, proliferation and VEGF expression in human umbilical vein endothelial cells
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Inhibitory effect of Andrographis paniculata extract and its active diterpenoids on platelet aggregation
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Selective conjugated fatty acids inhibit guinea pig platelet aggregation
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The lipoxygenase–cyclooxygenase inhibitor licofelone prevents thromboxane A2-mediated cardiovascular derangement triggered by the inflammatory peptide fMLP in the rabbit
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Aripiprazole and its human metabolite are partial agonists at the human dopamine D2 receptor, but the rodent metabolite displays antagonist properties
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Distinct roles of diverse nuclear factor-κB complexes in neuropathological mechanisms
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Suppression of ischemia/reperfusion liver injury by histamine H4 receptor stimulation in rats
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Mechanisms underlying hyperpolarization evoked by P2Y receptor activation in mouse distal colon
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Differential action of anti-emetic drugs on defecation and emesis induced by prostaglandin E2 in the ferret
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The prokinetic-like activity of ghrelin in rat isolated stomach is mediated via cholinergic and tachykininergic motor neurones
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Potentiation by neuropeptide Y of 5HT2A receptor-mediated contraction in porcine coronary artery
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Effects of rosiglitazone and metformin on postprandial paraoxonase-1 and monocyte chemoattractant protein-1 in human immunodeficiency virus-infected patients with lipodystrophy
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Increased NADPH oxidase activity mediates spontaneous aortic tone in genetically hypertensive rats
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Dextromethorphan, 3-methoxymorphinan, and dextrorphan have local anaesthetic effect on sciatic nerve blockade in rats
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Effect of tamsulosin on spontaneous bladder contraction in conscious rats with bladder outlet obstruction: Comparison with effect on intraurethral pressure
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Modern concepts of acute and chronic pain management
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LPS from Escherichia coli protects against indomethacin-induced gastropathy in rats—Role of ATP-sensitive potassium channels
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Protective effects of meloxicam on aluminum overload-induced cerebral damage in mice
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Neuronal conditions of spinal cord in dermatitis are improved by olopatadine
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E3024, 3-but-2-ynyl-5-methyl-2-piperazin-1-yl-3,5-dihydro-4H-imidazo[4,5-d]pyridazin-4-one tosylate, is a novel, selective and competitive dipeptidyl peptidase-IV inhibitor
Fulltext Access 7 Pages 2006
Combined effect of probucol and insulin on renal damage in diabetic rats fed a high cholesterol diet
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TEMPOL, a membrane-permeable radical scavenger, attenuates peroxynitrite- and superoxide anion-enhanced carrageenan-induced paw edema and hyperalgesia: A key role for superoxide anion
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The location of photodegradable nitric oxide store in the mouse stomach fundus
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Inhibition of the Na+–K+–2Cl−-cotransporter in choroid plexus attenuates traumatic brain injury-induced brain edema and neuronal damage
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Pharmacological therapies against soman-induced seizures in rats 30 min following onset and anticonvulsant impact
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Activation of adenosine A1 receptor modulates dopamine D1 receptor activity in stably cotransfected human embryonic kidney 293 cells
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YM440, a novel hypoglycemic agent, protects against nephropathy in Zucker fatty rats via plasma triglyceride reduction
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