Anti-nociceptive effect of thalidomide on zymosan-induced experimental articular incapacitation Fulltext Access 9 Pages 2006
Upstream signaling of protein kinase C-ε in xenon-induced pharmacological preconditioning: Implication of mitochondrial adenosine triphosphate dependent potassium channels and phosphatidylinositol-dependent kinase-1 Fulltext Access 9 Pages 2006
Preventive effects of (5R)-5-hydroxytriptolide on concanavalin A-induced hepatitis Fulltext Access 9 Pages 2006
The nitric oxide synthesis/pathway mediates the inhibitory serotoninergic responses of the pressor effect elicited by sympathetic stimulation in diabetic pithed rats Fulltext Access 9 Pages 2006
Reinstatement of nicotine-conditioned place preference by drug priming: Effects of calcium channel antagonists Fulltext Access 9 Pages 2006
Pentoxifylline and its major oxidative metabolites exhibit different pharmacological properties Fulltext Access 9 Pages 2006
Potential vascular α1-adrenoceptor blocking properties of an array of 5-HT receptor ligands in the rat Fulltext Access 9 Pages 2006
Different effects of 7-nitroindazole in reserpine-induced hypolocomotion in two strains of mice Fulltext Access 9 Pages 2006
5-HT1A receptors in endogenous regulation of neuropathic hypersensitivity in the rat Fulltext Access 9 Pages 2006
Nitric oxide-mediated effect of nipradilol, an α- and β-adrenergic blocker, on glutamate neurotoxicity in rat cortical cultures Fulltext Access 9 Pages 2006
Lack of interaction between prostaglandin E2 receptor subtypes in regulating adenylyl cyclase activity in cultured rat dorsal root ganglion cells Fulltext Access 9 Pages 2006
Pharmacological characterization in vitro of EP2306 and EP2302, potent inhibitors of squalene synthase and lipid biosynthesis Fulltext Access 9 Pages 2006
Direct effects of nitric oxide on histamine release from rat enterochromaffin-like cells Fulltext Access 9 Pages 2006
Cytoprotection by lithium and valproate varies between cell types and cellular stresses Fulltext Access 9 Pages 2006
Short courses of low dose dexamethasone delay bleomycin-induced lung fibrosis in rats Fulltext Access 9 Pages 2006
Poloxamer 407 (P-407)-mediated reduction in the gene expression of ATP-binding-cassette transporter A1 may contribute to increased cholesterol in peripheral tissues of P-407-treated rats Fulltext Access 9 Pages 2006
Ca2+ channel activating action of maitotoxin in cultured brainstem neurons Fulltext Access 9 Pages 2006
Lipopolysaccharide downregulates the expressions of intestinal pregnane X receptor and cytochrome P450 3a11 Fulltext Access 9 Pages 2006
20(S)-ginsenoside Rh2, a newly identified active ingredient of ginseng, inhibits NMDA receptors in cultured rat hippocampal neurons Fulltext Access 9 Pages 2006
Osteogenic actions of the anti-diabetic drug metformin on osteoblasts in culture Fulltext Access 9 Pages 2006
Involvement of Rho signaling in PAR2-mediated regulation of neutrophil adhesion to lung epithelial cells Fulltext Access 9 Pages 2006
Suppression by WIN55212-2, a cannabinoid receptor agonist, of inflammatory reactions in mouse ear: Interference with the actions of an endogenous ligand, 2-arachidonoylglycerol Fulltext Access 9 Pages 2006
Mechanisms underlying the impaired EDHF-type relaxation response in mesenteric arteries from Otsuka Long-Evans Tokushima Fatty (OLETF) rats Fulltext Access 9 Pages 2006
High glucose enhances inducible nitric oxide synthase expression. Role of protein kinase C-βII Fulltext Access 9 Pages 2006
Activation of P2Y1 receptor triggers two calcium signaling pathways in bone marrow erythroblasts Fulltext Access 9 Pages 2006
Activity and expression of semicarbazide-sensitive benzylamine oxidase in a rodent model of diabetes: Interactive effects with methylamine and alpha-aminoguanidine Fulltext Access 9 Pages 2006
Histamine-induced vasodilation and vasoconstriction in the mesenteric resistance artery of the rat Fulltext Access 9 Pages 2006
The analgesic efficacy of partial opioid agonists is increased in mice with targeted inactivation of the α2A-adrenoceptor gene Fulltext Access 9 Pages 2006
Quercetin, a bioflavonoid, accelerates TNF-α-induced growth inhibition and apoptosis in MC3T3-E1 osteoblastic cells Fulltext Access 9 Pages 2006
Purine P1 receptor-dependent immunostimulatory effects of antiviral acyclic analogues of adenine and 2,6-diaminopurine Fulltext Access 9 Pages 2006
Stimulation of soluble guanylyl cyclase by BAY 41-2272 relaxes anococcygeus muscle: Interaction with nitric oxide Fulltext Access 9 Pages 2006
Heme oxygenase 1 mediates anti-inflammatory effects of 2′,4′,6′-tris(methoxymethoxy) chalcone Fulltext Access 9 Pages 2006
Long-term blockade of angiotensin AT1 receptors increases survival of obese Zucker rats Fulltext Access 9 Pages 2006
Anti-inflammatory activity of non-nucleoside adenosine deaminase inhibitor FR234938 Fulltext Access 9 Pages 2006
Prostaglandins modulate nitric oxide synthase activity early in time in the uterus of estrogenized rat challenged with lipopolysaccharide Fulltext Access 9 Pages 2006
Contribution of endothelin receptors and cyclooxygenase-derivatives to the altered response of the rabbit renal artery to endothelin-1 in diabetes Fulltext Access 9 Pages 2006
17-β-estradiol inhibits transforming-growth-factor-β-induced MCF-7 cell migration by Smad3-repression Fulltext Access 9 Pages 2006
Discriminative stimulus effects of GHB and GABAB agonists are differentially attenuated by CGP35348 Fulltext Access 9 Pages 2006
Folic acid reverses endothelial dysfunction induced by inhibition of tetrahydrobiopterin biosynthesis Fulltext Access 9 Pages 2006
Vasoconstrictor prostanoids may be involved in reduced coronary reactive hyperemia after ischemia–reperfusion in anesthetized goats Fulltext Access 9 Pages 2006
Neurogenic insulin resistance in guinea-pigs with cisplatin-induced neuropathy Fulltext Access 9 Pages 2006
Behavioral and neurobiological effects of the enkephalinase inhibitor RB101 relative to its antidepressant effects Fulltext Access 9 Pages 2006
The nitric oxide-cyclic GMP-protein kinase G-K+ channel pathway participates in the antiallodynic effect of spinal gabapentin Fulltext Access 9 Pages 2006
Modulation of p-glycoprotein and breast cancer resistance protein by some prescribed corticosteroids Fulltext Access 9 Pages 2006
Effects of cyamemazine on hERG, INa, ICa, Ito, Isus and IK1 channel currents, and on the QTc interval in guinea pigs Fulltext Access 9 Pages 2006
Nonsteroidal anti-inflammatory drugs inhibit the growth of C6 and U138-MG glioma cell lines Fulltext Access 9 Pages 2006
Peroxisome proliferator-activated receptor gamma agonists as therapy for chronic airway inflammation Fulltext Access 9 Pages 2006
Mucosally-directed adrenergic nerves and sympathomimetic drugs enhance non-intimate adherence of Escherichia coli O157:H7 to porcine cecum and colon Fulltext Access 9 Pages 2006
Effects of resistance exercise and growth hormone administration at low doses on lipid metabolism in middle-aged female rats Fulltext Access 9 Pages 2006
The cannabinoid agonist WIN 55,212-2 inhibits TNF-α-induced neutrophil transmigration across ECV304 cells Fulltext Access 9 Pages 2006
Comparison between effects of intravenous and nebulized histamine in guinea pigs: Correlation between changes in respiratory mechanics and exhaled nitric oxide Fulltext Access 9 Pages 2006
Histamine decreases myogenic tone in rat cerebral arteries by H2-receptor-mediated KV channel activation, independent of endothelium and cyclic AMP Fulltext Access 9 Pages 2006
Effects of the selective delta opioid agonist SNC80 on cocaine- and food-maintained responding in rhesus monkeys Fulltext Access 9 Pages 2006
Influence of pharmacologically-induced experimental anxiety on nociception and antinociception in rats Fulltext Access 9 Pages 2006
Isorhamnetin prevent endothelial cell injuries from oxidized LDL via activation of p38MAPK Fulltext Access 9 Pages 2006
Involvement of calcium-mediated apoptotic signals in H2O2-induced MIN6N8a cell death Fulltext Access 9 Pages 2006
Pathophysiological role of mast cells in collagen-induced arthritis: Study with a cysteinyl leukotriene receptor antagonist, montelukast Fulltext Access 9 Pages 2006
Antidepressant properties of rotigotine in experimental models of depression Fulltext Access 9 Pages 2006
Mediation of glutamatergic receptors and nitric oxide on striatal dopamine release evoked by anatoxin-a. An in vivo microdialysis study Fulltext Access 9 Pages 2006
Hypotonic shock stimulates ascorbate release from coronary artery endothelial cells by a Ca2+-independent pathway Fulltext Access 9 Pages 2006
β-endorphin differentially affects inflammation in two inbred rat strains Fulltext Access 9 Pages 2006
Thromboxane A2 receptor-mediated G12/13-dependent glial morphological change Fulltext Access 9 Pages 2006
The direct antioxidative and anti-inflammatory effects of peroxisome proliferator-activated receptors ligands are associated with the inhibition of angiotensin converting enzyme expression in streptozotocin-induced diabetic rat aorta Fulltext Access 9 Pages 2006
High permeability of the anionic form restricts accumulation of indomethacin by cultured gastric surface epithelial cells exposed to low apical pH Fulltext Access 9 Pages 2006
4-O-methylgallic acid down-regulates endothelial adhesion molecule expression by inhibiting NF-κB-DNA-binding activity Fulltext Access 9 Pages 2006
Adenosine A1 receptor antagonist versus montelukast on airway reactivity and inflammation Fulltext Access 9 Pages 2006
Differential effects of cyclooxygenase inhibitors on intracerebroventricular colchicine-induced dysfunction and oxidative stress in rats Fulltext Access 9 Pages 2006
Spinal and pontine α2-adrenoceptors have opposite effects on pain-related behavior in the neuropathic rat Fulltext Access 9 Pages 2006
Fluorescence- and luminescence-based methods for the determination of affinity and activity of neuropeptide Y2 receptor ligands Fulltext Access 9 Pages 2006
Piceatannol stimulates osteoblast differentiation that may be mediated by increased bone morphogenetic protein-2 production Fulltext Access 9 Pages 2006
Radiocontrast media cause dephosphorylation of Akt and downstream signaling targets in human renal proximal tubular cells Fulltext Access 9 Pages 2006
Basis for dosing time-dependent change in the anti-tumor effect of imatinib in mice Fulltext Access 9 Pages 2006
The new orally active iron chelator ICL670A exhibits a higher antiproliferative effect in human hepatocyte cultures than O-trensox Fulltext Access 9 Pages 2006
The involvement of a cyclooxygenase 1 gene-derived protein in the antinociceptive action of paracetamol in mice Fulltext Access 9 Pages 2006
Broad therapeutic treatment window of [Nle4, D-Phe7]α-melanocyte-stimulating hormone for long-lasting protection against ischemic stroke, in Mongolian gerbils Fulltext Access 9 Pages 2006
Molecular cloning and pharmacological characterization of serotonin 5-HT3A receptor subtype in dog Fulltext Access 9 Pages 2006
The effects of a novel phosphodiesterase 7A and -4 dual inhibitor, YM-393059, on T-cell-related cytokine production in vitro and in vivo Fulltext Access 9 Pages 2006
GABAB receptor antagonism abolishes the learning impairments in rats with chronic atypical absence seizures Fulltext Access 9 Pages 2006
Protective effect of calceolarioside on adriamycin-induced cardiomyocyte toxicity Fulltext Access 9 Pages 2006
Nucleotide analogues with immunobiological properties: 9-[2-Hydroxy-3-(phosphonomethoxy)propyl]-adenine (HPMPA), -2,6-diaminopurine (HPMPDAP), and their N6-substituted derivatives Fulltext Access 9 Pages 2006
TRPV1 antagonist, SB-366791, inhibits glutamatergic synaptic transmission in rat spinal dorsal horn following peripheral inflammation Fulltext Access 9 Pages 2006
ATP stimulates interleukin-6 production via P2Y receptors in human HaCaT keratinocytes Fulltext Access 9 Pages 2006
β-glucan ameliorates methotrexate-induced oxidative organ injury via its antioxidant and immunomodulatory effects Fulltext Access 9 Pages 2006
Induction of Fas clustering and apoptosis by coral prostanoid in human hormone-resistant prostate cancer cells Fulltext Access 9 Pages 2006
Dipyridamole activation of mitogen-activated protein kinase phosphatase-1 mediates inhibition of lipopolysaccharide-induced cyclooxygenase-2 expression in RAW 264.7 cells Fulltext Access 9 Pages 2006
Synergistic induction of apoptosis by sulindac and arsenic trioxide in human lung cancer A549 cells via reactive oxygen species-dependent down-regulation of survivin Fulltext Access 9 Pages 2006
Nimesulide-induced antipyresis in rats involves both cyclooxygenase-dependent and independent mechanisms Fulltext Access 9 Pages 2006
α1D-adrenoceptor-induced relaxation on rat carotid artery is impaired during the endothelial dysfunction evoked in the early stages of hyperhomocysteinemia Fulltext Access 9 Pages 2006
Clonidine inhibits the canine external carotid vasodilatation to capsaicin by α2A/2C-adrenoceptors Fulltext Access 9 Pages 2006
Comparative effects of lidocaine and tramadol on injured peripheral nerves Fulltext Access 9 Pages 2006
Function of multidrug resistance-associated protein 2 in acute hepatic failure rats Fulltext Access 9 Pages 2006
Non-cannabinoid CB1, non-cannabinoid CB2 antinociceptive effects of several novel compounds in the PPQ stretch test in mice Fulltext Access 9 Pages 2006
Angiotensin AT4 receptor ligand interaction with cystinyl aminopeptidase and aminopeptidase N: [125I]Angiotensin IV only binds to the cystinyl aminopeptidase apo-enzyme Fulltext Access 9 Pages 2006
New targets for pharmacological intervention in the glutamatergic synapse Fulltext Access 9 Pages 2006
Blockade of HERG human K+ channel and IKr of guinea pig cardiomyocytes by prochlorperazine Fulltext Access 9 Pages 2006
Involvement of the multidrug resistance transporters in cisplatin-induced neuropathy in rats. Comparison with the chronic constriction injury model and monoarthritic rats Fulltext Access 9 Pages 2006
Protective effects of minocycline on 3,4-methylenedioxymethamphetamine-induced neurotoxicity in serotonergic and dopaminergic neurons of mouse brain Fulltext Access 9 Pages 2006