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Pharmacology Research Articles

Zinc and 17β-estradiol induce modifications in Na+/H+ exchanger and pyruvate kinase activity through protein kinase C in isolated mantle/gonad cells of Mytilus galloprovincialis
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Prenatal ethanol exposure: Sex differences in anxiety and anxiolytic response to a 5-HT1A agonist
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Acute effects of nicotine on attention and response inhibition
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Role of dopamine and glutamate receptors in cocaine-induced social effects in isolated and grouped male OF1 mice
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Lead-induced catalase activity differentially modulates behaviors induced by short-chain alcohols
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Behavioral differences between subgroups of rats with high and low threshold to clonic convulsions induced by DMCM, a benzodiazepine inverse agonist
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Antioxidant defense of rainbow trout (Oncorhynchus mykiss) in relation to dietary n-3 highly unsaturated fatty acids and vitamin E contents
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Seasonal modulation of free radical metabolism in estivating land snails Helix aspersa
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Modulation of Ah receptor and CYP1A1 expression by α-naphthoflavone in rainbow trout hepatocytes
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Effects of nonylphenol on hepatic testosterone metabolism and the expression of acute phase proteins in winter flounder (Pleuronectes americanus): Comparison to the effects of Saint John's Wort
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Molecular characterization and expression of the gene encoding aspartate aminotransferase from the Pacific oyster Crassostrea gigas exposed to environmental stressors
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Metabolic enzyme activities in black bream (Acanthopagrus butcheri) from the Swan-Canning Estuary, Western Australia
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mRNA expression of antioxidant enzymes (SOD, CAT and GSH-Px) and lipid peroxidative stress in liver of Atlantic salmon (Salmo salar) exposed to hyperoxic water during smoltification
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Effect of prolonged nicotine infusion on response of rat catecholamine biosynthetic enzymes to restraint and cold stress
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Increased nociceptive response in mice lacking the adenosine A1 receptor
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Intrathecal morphine and ketorolac analgesia after surgery: comparison of spontaneous and elicited responses in rats
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The effects of racemic ketamine on painful stimulation of skin and viscera in human subjects
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Transcutaneous electrical nerve stimulation activates peripherally located alpha-2A adrenergic receptors
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Increased placebo analgesia over time in irritable bowel syndrome (IBS) patients is associated with desire and expectation but not endogenous opioid mechanisms
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Stages of change in readiness to adopt a self-management approach to chronic pain: the moderating role of early-treatment stage progression in predicting outcome
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Efficacy of pregabalin in neuropathic pain evaluated in a 12-week, randomised, double-blind, multicentre, placebo-controlled trial of flexible- and fixed-dose regimens
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Thermoreceptive innervation of human glabrous and hairy skin: a contact heat evoked potential analysis
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Modulatory effects of estrogen and progesterone on colorectal hyperalgesia in the rat
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The possible role of the NO-cGMP pathway in nociception: Different spinal and supraspinal action of enzyme blockers on rat dorsal horn neurones
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A prognostic approach to defining chronic pain
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Effect of calcium channel modulators on temperature regulation in ovariectomized rats
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Reengineering the pharmaceutical industry by crash-testing molecules
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Keynote review: Medicinal chemistry strategies to CB1 cannabinoid receptor antagonists
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Biological networks and analysis of experimental data in drug discovery
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Keynote review: Progress in targeting HIV-1 entry
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Modelling enzyme reaction mechanisms, specificity and catalysis
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Oral administration of the 5-HT6 receptor antagonists SB-357134 and SB-399885 improves memory formation in an autoshaping learning task
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MDMA (ecstasy) effects in pubescent rats: Males are more sensitive than females
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Choto-san, a Kampo formula, improves chronic cerebral hypoperfusion-induced spatial learning deficit via stimulation of muscarinic M1 receptor
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Muscarinic and nicotinic receptor modulation of object and spatial n-back working memory in humans
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Combined effects of methamphetamine and zolpidem on performance and mood during simulated night shift work
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Seizure-induced oxidative stress in rat brain regions: blockade by nNOS inhibition
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Endocannabinoids and 3,4-methylenedioxymethamphetamine (MDMA) interaction
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Cortical representation of experimental tooth pain in humans
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Anxiolytic-like actions of centrally-administered neuropeptide Y, but not galanin, in C57BL/6J mice
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Delta-9-tetrahydrocannabinol differentially suppresses emesis versus enhanced locomotor activity produced by chemically diverse dopamine D2/D3 receptor agonists in the least shrew (Cryptotis parva)
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Estrogen-priming can enhance progesterone's anti-seizure effects in part by increasing hippocampal levels of allopregnanolone
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Differential effects of mild repeated restraint stress on behaviors and GABAA receptors in male and female rats
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Sensitized effects of neuropeptide Y on multiple ingestive behaviors in P rats following ethanol abstinence
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Rewarding properties of the stereoisomers of 4-methylaminorex: Involvement of the dopamine system
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The effect of filter vent blocking and smoking topography on carbon monoxide levels in smokers
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Oxazepam does not modulate the behavioral effects of d-amphetamine in humans
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Acute and chronic effects of MDMA on molecular mechanisms implicated in memory formation in rat hippocampus: Surface expression of CaMKII and NMDA receptor subunits
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Effects of sublethal doses of fipronil on the behavior of the honeybee (Apis mellifera)
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Role of the cholinergic system in the rat basolateral amygdala on morphine-induced conditioned place preference
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In Vivo Pharmacology and Antidiarrheal Efficacy of a Thiazolidinone CFTR Inhibitor in Rodents
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Neural correlates of painful genital touch in women with vulvar vestibulitis syndrome
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Interleukin-1 antagonizes morphine analgesia and underlies morphine tolerance
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Effects of a workplace physical exercise intervention on the intensity of headache and neck and shoulder symptoms and upper extremity muscular strength of office workers: A cluster randomized controlled cross-over trial
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Duloxetine vs. placebo in patients with painful diabetic neuropathy
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Effect of the cannabinoid CB1 receptor antagonist, SR141716, on nociceptive response and nerve demyelination in rodents with chronic constriction injury of the sciatic nerve
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Changes in P2X3 receptor expression in the trigeminal ganglion following monoarthritis of the temporomandibular joint in rats
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Central cyclooxygenase inhibitors reduced IL-1β-induced hyperalgesia in temporomandibular joint of freely moving rats
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Effect of persistent monoarthritis of the temporomandibular joint region on acute mustard oil-induced excitation of trigeminal subnucleus caudalis neurons in male and female rats
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Inhibition of nociceptive dural input in the trigeminal nucleus caudalis by somatostatin receptor blockade in the posterior hypothalamus
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Signal transduction pathways of group I metabotropic glutamate receptor-induced long-term depression at sensory spinal synapses
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Evaluation of Dodecylmaltoside as a Permeability Enhancer for Insulin Using Human Carcinoma Cells
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Using a Novel Multicompartment Dissolution System to Predict the Effect of Gastric pH on the Oral Absorption of Weak Bases with Poor Intrinsic Solubility
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Gender-related effects of chronic non-malignant pain and opioid therapy on plasma levels of macrophage migration inhibitory factor (MIF)
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Physical Stability of Sonicated Arsonoliposomes: Effect of Calcium Ions
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Effects of acidic N + 1 residues on asparagine deamidation rates in solution and in the solid state
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Programmed Humidifying in Drug Stability Experiments
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An Investigation of the Factors Controlling the Adsorption of Protein Antigens to Anionic PLG Microparticles
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Factors Affecting Shear Thickening Behavior of a Concentrated Injectable Suspension of Levodopa
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Polysorbate 80 and Cremophor EL Micelles Deaggregate and Solubilize Nystatin at the Core-Corona Interface
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Biodistribution characteristics of all-trans retinoic acid incorporated in liposomes and polymeric micelles following intravenous administration
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Isothermal Crystallization Kinetics of Lidocaine in Supersaturated Lidocaine/Polyacrylate Pressure Sensitive Adhesive Systems
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Effect of Galactose Density on Asialoglycoprotein Receptor-Mediated Uptake of Galactosylated Liposomes
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Effects of New 4-Aryl-1,4-Dihydropyridines and 4-Arylpyridines on Drug Efflux Mediated by Multidrug Resistance-Associated Protein 1
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Disposition and Biotransformation of the Acetylenic Retinoid Tazarotene in Humans
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A placebo-controlled randomized clinical trial of perioperative administration of gabapentin, rofecoxib and their combination for spontaneous and movement-evoked pain after abdominal hysterectomy
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The development and preliminary validation of the Profile of Chronic Pain: Extended Assessment Battery
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Why is a treatment aimed at psychosocial factors not effective in patients with (sub)acute low back pain?
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Use of a novel thermal operant behavioral assay for characterization of orofacial pain sensitivity
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Acute pain: individual patient meta-analysis shows the impact of different ways of analysing and presenting results
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Pathophysiology of migraine headache: Insight from pharmacology and genetics
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Neurodegeneration and neuroprotective strategies after traumatic brain injury
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Reconditioning of drug-related cues: A potential contributor to relapse after drug reexposure
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Dietary cadmium exposure attenuates d-amphetamine-evoked [3H]dopamine release from striatal slices and methamphetamine-induced hyperactivity
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The effect of environmental stress on absolute and mass-specific scope for growth in Daphnia magna Strauss
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Effects of 17α-ethynylestradiol on sexual development of male western mosquitofish (Gambusia affinis)
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Thalamic thermo-algesic transmission: ventral posterior (VP) complex versus VMpo in the light of a thalamic infarct with central pain
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Parent-child interactions among children with juvenile fibromyalgia, arthritis, and healthy controls
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Occurrence of Pharmaceutically Acceptable Anions and Cations in the Cambridge Structural Database
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Tumor necrosis factor α and interleukin-1β stimulate the expression of cyclooxygenase II but do not alter prostaglandin E2 receptor mRNA levels in cultured dorsal root ganglia cells
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Ketamine and postoperative pain - a quantitative systematic review of randomised trials
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Activation of p38 MAPK in primary afferent neurons by noxious stimulation and its involvement in the development of thermal hyperalgesia
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Nociceptor-specific gene deletion using heterozygous NaV1.8-Cre recombinase mice
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Neurotensin activation of the NTR1 on spinally-projecting serotonergic neurons in the rostral ventromedial medulla is antinociceptive
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Change of dorsal horn neurochemistry in a mouse model of neuropathic cancer pain
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Unilateral spinal nerve ligation leads to an asymmetrical distribution of mast cells in the thalamus of female but not male mice
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The organizational and activational effects of sex hormones on tactile and thermal hypersensitivity following lumbar nerve root injury in male and female rats
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Do men and women differ in their response to interdisciplinary chronic pain management?
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Nitrous oxide analgesia in humans: acute and chronic tolerance
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Effects of amitriptyline and gabapentin on bilateral hyperalgesia observed in an animal model of unilateral axotomy
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