A mutation in the local anaesthetic binding site abolishes toluene effects in sodium channels Fulltext Access 10 Pages 2005
Phosphodiesterase 5 and effects of sildenafil on cerebral arteries of man and guinea pig Fulltext Access 10 Pages 2005
5-HT1A receptor-mediated G protein activation assessed by [35S]GTPγS binding in rat cerebral cortex Fulltext Access 10 Pages 2005
Effects of angiotensin I-converting enzyme inhibitor and angiotensin II type 1 receptor blocker on the right ventricular sarcoglycans and dystrophin after left coronary artery ligation Fulltext Access 10 Pages 2005
Goniothalamin induces cell cycle-specific apoptosis by modulating the redox status in MDA-MB-231 cells Fulltext Access 10 Pages 2005
The role of NF-κB signaling in impaired liver tissue repair in thioacetamide-treated type 1 diabetic rats Fulltext Access 10 Pages 2005
Characterization of KATP-channels in rat basilar and middle cerebral arteries: Studies of vasomotor responses and mRNA expression Fulltext Access 10 Pages 2005
Dose- and duration-dependent effects of betahistine dihydrochloride treatment on histamine turnover in the cat Fulltext Access 10 Pages 2005
Selective in vivo anti-inflammatory action of the galactolipid monogalactosyldiacylglycerol Fulltext Access 10 Pages 2005
Multiple actions of U-37883A, an ATP-sensitive K+ channel blocker, on membrane currents in pig urethra Fulltext Access 10 Pages 2005
[3H]N-[4-(3,4-dihydro-6,7-dimethoxyisoquinolin-2(1H)-yl)butyl]-2-methoxy-5-methylbenzamide: A novel sigma-2 receptor probe Fulltext Access 10 Pages 2005
FK962, a novel enhancer of somatostatin release, exerts cognitive-enhancing actions in rats Fulltext Access 10 Pages 2005
Involvement of C3435T and G2677T multidrug resistance gene polymorphisms in release of cytokines from peripheral blood mononuclear cells treated with methotrexate and dexamethasone Fulltext Access 10 Pages 2005
Blockade of 5-HT3 receptor with MDL72222 and Y25130 reduces β-amyloid protein (25-35)-induced neurotoxicity in cultured rat cortical neurons Fulltext Access 10 Pages 2005
MEN16132, a novel potent and selective nonpeptide antagonist for the human bradykinin B2 receptor. In vitro pharmacology and molecular characterization Fulltext Access 10 Pages 2005
Jak2 tyrosine kinase prevents angiotensin II-mediated inositol 1,4,5 trisphosphate receptor degradation Fulltext Access 10 Pages 2005
Endothelin-1 activation of JAK2 in vascular smooth muscle cells involves NAD(P)H oxidase-derived reactive oxygen species Fulltext Access 10 Pages 2005
Angiotensin II type 2 receptor-mediated vasodilation. Focus on bradykinin, NO and endothelium-derived hyperpolarizing factor(s) Fulltext Access 10 Pages 2005
Expression, localisation and function of ACE and chymase in normal and atherosclerotic human coronary arteries Fulltext Access 10 Pages 2005
Angiotensin II-induced hypertension in mice caused an increase in insulin secretion Fulltext Access 10 Pages 2005
Evaluation of nasal barrier dysfunction at acute- and late-phase reactions in a guinea pig model of allergic rhinitis Fulltext Access 10 Pages 2005
Vascular reactivity of mesenteric arteries and veins to endothelin-1 in a murine model of high blood pressure Fulltext Access 10 Pages 2005
The biology of exhaled nitric oxide (NO) in ischemia-reperfusion-induced lung injury: A tale of dynamism of NO production and consumption Fulltext Access 10 Pages 2005
Aripiprazole's low intrinsic activities at human dopamine D2L and D2S receptors render it a unique antipsychotic Fulltext Access 10 Pages 2005
Combined effect of probucol and insulin on cataracts of diabetic rats fed a high cholesterol diet Fulltext Access 10 Pages 2005
Evidence for two atypical conformations of beta-adrenoceptors and their interaction with Gi proteins Fulltext Access 10 Pages 2005
Cloning and functional characterization of dog transient receptor potential vanilloid receptor-1 (TRPV1) Fulltext Access 10 Pages 2005
Effects of a selective bradykinin B1 receptor antagonist on increased plasma extravasation in streptozotocin-induced diabetic rats: Distinct vasculopathic profile of major key organs Fulltext Access 10 Pages 2005
Anxiolytic-like effects of mGlu1 and mGlu5 receptor antagonists in rats Fulltext Access 10 Pages 2005
Effects of desipramine and tramadol in a chronic mild stress model in mice are altered by yohimbine but not by pindolol Fulltext Access 10 Pages 2005
Pharmacokinetic/pharmacodynamic modelling of the anti-hyperalgesic and anti-nociceptive effect of adenosine A1 receptor partial agonists in neuropathic pain Fulltext Access 10 Pages 2005
Effects of the high-efficacy 5-HT1A receptor agonist, F 13640 in the formalin pain model: A c-Fos study Fulltext Access 10 Pages 2005
Tacrolimus (FK506) has protective actions against murine bleomycin-induced acute lung injuries Fulltext Access 10 Pages 2005
Endothelial mechanisms underlying responses to acetylcholine in the horse deep dorsal penile vein Fulltext Access 10 Pages 2005
Differential effects of 5-HT2C receptor ligands on place conditioning and locomotor activity in rats Fulltext Access 10 Pages 2005
Effects of betahistine on the spatiotemporal response properties of vestibulospinal neurons to labyrinthine volleys Fulltext Access 10 Pages 2005
The influence of sulindac on diabetic cardiomyopathy: A non-invasive evaluation by Doppler echocardiography in streptozotocin-induced diabetic rats Fulltext Access 10 Pages 2005
Mitochondrial dysfunction is related to necrosis-like programmed cell death induced by A23187 in CEM cells Fulltext Access 10 Pages 2005
α2A-Adrenoceptors regulate d-amphetamine-induced hyperactivity and behavioural sensitization in mice Fulltext Access 10 Pages 2005
Pharmacological characterization of the TRPV1 receptor antagonist JYL1421 (SC0030) in vitro and in vivo in the rat Fulltext Access 10 Pages 2005
YC-1-inhibited proliferation of rat mesangial cells through suppression of cyclin D1-Independent of cGMP pathway and partially reversed by p38 MAPK inhibitor Fulltext Access 10 Pages 2005
Effects of a 5-HT7 receptor antagonist DR4004 on the exploratory behavior in a novel environment and on brain monoamine dynamics in mice Fulltext Access 10 Pages 2005
Electrophysiological effects of azimilide in an in vitro model of simulated-ischemia and reperfusion in guinea-pig ventricular myocardium Fulltext Access 10 Pages 2005
Effects of anticonvulsants on soman-induced epileptiform activity in the guinea-pig in vitro hippocampus Fulltext Access 10 Pages 2005
Interference of neutrophil-platelet interaction by YC-1: A cGMP-dependent manner on heterotypic cell-cell interaction Fulltext Access 10 Pages 2005
The effects of AMPA receptor antagonists in models of stroke and neurodegeneration Fulltext Access 10 Pages 2005
Vasopeptidase inhibition has beneficial cardiac effects in spontaneously diabetic Goto-Kakizaki rats Fulltext Access 10 Pages 2005
Impact and mechanisms of action of neurotensin on cardiac contractility in the rat left ventricle Fulltext Access 10 Pages 2005
Bioavailability enhancement of a COX-2 inhibitor, BMS-347070, from a nanocrystalline dispersion prepared by spray-drying Fulltext Access 10 Pages 2005
Antimalarial remedies in French Guiana: A knowledge attitudes and practices study Fulltext Access 10 Pages 2005
Antioxidant activity and antiproliferative action of methanolic extract of Geum quellyon Sweet roots in human tumor cell lines Fulltext Access 10 Pages 2005
Pharmacists' and Technicians' Perceptions and Attitudes Toward Dispensing Buprenorphine/Naloxone to Patients with Opioid Dependence Fulltext Access 10 Pages 2005
Drug Therapy Concerns Questionnaire: Initial Development and Refinement Fulltext Access 10 Pages 2005
Pharmacist Telemonitoring of Antidepressant Use: Effects on Pharmacist-Patient Collaboration Fulltext Access 10 Pages 2005
Interspecies Scaling of Biliary Excreted Drugs: A Comparison of Several Methods* Fulltext Access 10 Pages 2005
Enhanced Buccal Mucosal Retention and Reduced Buccal Permeability of Estradiol in the Presence of Padimate O and Azone®: A Mechanistic Study Fulltext Access 10 Pages 2005
Using Terahertz Pulsed Spectroscopy to Quantify Pharmaceutical Polymorphism and Crystallinity Fulltext Access 10 Pages 2005
Mass Spectral Analyses of Labile DOTA-NHS and Heterogeneity Determination of DOTA or DM1 Conjugated Anti-PSMA Antibody for Prostate Cancer Therapy Fulltext Access 10 Pages 2005
Solid Films of Blended Poly(Vinyl Alcohol)/Poly(Vinyl Pyrrolidone) for Topical S-Nitrosoglutathione and Nitric Oxide Release Fulltext Access 10 Pages 2005
Determination of the binding constant between alprostadil and alpha-cyclodextrin by capillary electrophoresis: Implications for a freeze-dried formulation Fulltext Access 10 Pages 2005
Effects of cysteine on the pharmacokinetics of oltipraz in rats with protein-calorie malnutrition Fulltext Access 10 Pages 2005
Kinetics of iron-mediated artemisinin degradation: Effect of solvent composition and iron salt Fulltext Access 10 Pages 2005
Effect of ion-exchange fiber structure on the binding and release of model salicylates Fulltext Access 10 Pages 2005
Enhanced absorption of 3-O-methyl glucose following gastrointestinal injury induced by repeated oral administration of 5-FU in mice Fulltext Access 10 Pages 2005
Glycoengineering: The effect of glycosylation on the properties of therapeutic proteins Fulltext Access 10 Pages 2005
Evaluation of Buccal Methyl-β-Cyclodextrin Toxicity on Human Oral Epithelial Cell Culture Model Fulltext Access 10 Pages 2005
The Impact of Pharmacologic and Genetic Knockout of P-Glycoprotein on Nelfinavir Levels in the Brain and Other Tissues in Mice Fulltext Access 10 Pages 2005
Expression of PPAR, RXR Isoforms and Fatty Acid Transporting Proteins in the Rat and Human Gastrointestinal Tracts Fulltext Access 10 Pages 2005
Screening of Bitterness-Suppressing Agents for Quinine: The Use of Molecularly Imprinted Polymers Fulltext Access 10 Pages 2005
Evaluation of the mouse prostate as a suitable model for the study of human prostate function Fulltext Access 10 Pages 2005
Simple pharmacological test battery to assess efficacy and side effect profile of centrally acting muscle relaxant drugs Fulltext Access 10 Pages 2005
Quantitative PCR assay for cytochromes P450 2B and 3A induction in rat precision-cut liver slices: Correlation study with induction in vivo Fulltext Access 10 Pages 2005
Protein kinase C distribution and translocation in rat myocardium: Methodological considerations Fulltext Access 10 Pages 2005
A high-throughput chemotaxis assay for pharmacological characterization of chemokine receptors: Utilization of U937 monocytic cells Fulltext Access 10 Pages 2005
Both β-adrenergic receptor stimulation and cardiac tissue type have important roles in elucidating the functional effects of IKs channel blockers in vitro Fulltext Access 10 Pages 2005
A new method to calculate the beat-to-beat instability of QT duration in drug-induced long QT in anesthetized dogs Fulltext Access 10 Pages 2005
HERG-Lite®: A novel comprehensive high-throughput screen for drug-induced hERG risk Fulltext Access 10 Pages 2005
Drugs effects on ventricular repolarization: A critical evaluation of the strengths and weaknesses of current methodologies and regulatory practices Fulltext Access 10 Pages 2005
Measurement of adhesion of human platelets in plasma to protein surfaces in microplates Fulltext Access 10 Pages 2005
The use of small interfering RNA to elucidate the activity and function of ion channel genes in an intact tissue Fulltext Access 10 Pages 2005
The rat spinal cord slice: Its use in generating pharmacological evidence for cholinergic transmission using the α7 subtype of nicotinic receptors in the central autonomic nucleus Fulltext Access 10 Pages 2005
Mechanism of the Stationary Canalicular Excretion of Tributylmethyl Ammonium in Rats with a CCl4-Induced Acute Hepatic Injury Fulltext Access 10 Pages 2005
Studies of the anticancer potential of plants used in Bangladeshi folk medicine Fulltext Access 10 Pages 2005
Induction of apoptosis in human hepatoma cells by mycelia of Antrodia camphorata in submerged culture Fulltext Access 10 Pages 2005
Traditional knowledge of Kani tribals in Kouthalai of Tirunelveli hills, Tamil Nadu, India Fulltext Access 10 Pages 2005
Inhibitory effect of the Korean herbal medicine, Dae-Jo-Whan, on platelet-activating factor-induced platelet aggregation Fulltext Access 10 Pages 2005
Euonymus alatus prevents the hyperglycemia and hyperlipidemia induced by high-fat diet in ICR mice Fulltext Access 10 Pages 2005
Anti-bone resorption activity of deer antler aqua-acupunture, the pilose antler of Cervus korean TEMMINCK var. mantchuricus Swinhoe (Nokyong) in adjuvant-induced arthritic rats Fulltext Access 10 Pages 2005
An Uncaria tomentosa (cat's claw) extract protects mice against ozone-induced lung inflammation Fulltext Access 10 Pages 2005