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Daneshyari Pharmacology Journas Latest Articles

Pharmacology Research Articles

Investigation of toxic metabolites during drug development
Fulltext Access 10 Pages 2005
Infantile 4-tert-octylphenol exposure transiently inhibits rat ovarian steroidogenesis and steroidogenic acute regulatory protein (StAR) expression
Fulltext Access 10 Pages 2005
Upregulation of estrogen receptor expression in the uterus of ovariectomized B6C3F1 mice and Ishikawa cells treated with bromoethane
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Evaluation of oxime efficacy in nerve agent poisoning: Development of a kinetic-based dynamic model
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Azithromycin and erythromycin ameliorate the extent of colonic damage induced by acetic acid in rats
Fulltext Access 10 Pages 2005
Microarray analysis of altered gene expression in murine fibroblasts transformed by nickel(II) to nickel(II)-resistant malignant phenotype
Fulltext Access 10 Pages 2005
Variability of biological effects of silicas: Different degrees of activation of the fifth component of complement by amorphous silicas
Fulltext Access 10 Pages 2005
Oxidative mechanisms contributing to the developmental neurotoxicity of nicotine and chlorpyrifos
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Low dose DDT inhibition of hepatocarcinogenesis initiated by diethylnitrosamine in male rats: Possible mechanisms
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Effects of bisphenol A-related diphenylalkanes on vitellogenin production in male carp (Cyprinus carpio) hepatocytes and aromatase (CYP19) activity in human H295r adrenocortical carcinoma cells
Fulltext Access 10 Pages 2005
In silico prediction of harmful effects triggered by drugs and chemicals
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Microbial cell wall agents as an occupational hazard
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Toxicogenomics concepts and applications to study hepatic effects of food additives and chemicals
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Assessment of hepatotoxic liabilities by transcript profiling
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Regulation of death receptors-Relevance in cancer therapies
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Challenges in the adoption of new pharmacotherapeutics for addiction to alcohol and other drugs
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Involving the pharmaceutical and biotech communities in medication development for substance abuse
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Effects of fish-derived lipoprotein extracts on activation markers, Fas expression and apoptosis in peripheral blood lymphocytes
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Systemic responses to inhaled ozone in mice: cachexia and down-regulation of liver xenobiotic metabolizing genes
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Impact of maternal dietary exposure to endocrine-acting chemicals on progesterone receptor expression in microdissected hypothalamic medial preoptic areas of rat offspring
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Frutalin, a galactose-binding lectin, induces chemotaxis and rearrangement of actin cytoskeleton in human neutrophils: Involvement of tyrosine kinase and phosphoinositide 3-kinase
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Diazinon alters sperm chromatin structure in mice by phosphorylating nuclear protamines
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Organophosphorothionate pesticides inhibit the bioactivation of imipramine by human hepatic cytochrome P450s
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Toxicokinetics of acrylamide and glycidamide in B6C3F1 mice
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Doxycycline potentiates antitumor effect of cyclophosphamide in mice
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Arsenic exposure, urinary arsenic speciation, and peripheral vascular disease in blackfoot disease-hyperendemic villages in Taiwan
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Comparative metabolism of methacrylonitrile and acrylonitrile to cyanide using cytochrome P4502E1 and microsomal epoxide hydrolase-null mice
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Metabolomic and proteomic biomarkers for III-V semiconductors: Chemical-specific porphyrinurias and proteinurias
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Searching for biomarkers of developmental toxicity with microarrays: normal eye morphogenesis in rodent embryos
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Microglia is activated by astrocytes in trimethyltin intoxication
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Absorption and evaporation of N,N-diethyl-m-toluamide from human skin in vitro
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Differences between rats and mice in the involvement of the aryl hydrocarbon receptor in 4-vinylcyclohexene diepoxide-induced ovarian follicle loss
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Lead ions do not cause human lung cells to escape chromate-induced cytotoxicity
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Development of an enzyme-linked immunosorbent assay for podophyllotoxin
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Effect of 4-aminopyridine (4-AP) on the spontaneous activity and neuromuscular junction in the rat colon
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Differential effect of antioxidant treatment on plasma and tissue paraoxonase activity in hyperleptinemic rats
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Inhibition of poly(ADP-ribose) polymerase attenuates lung tissue damage after hind limb ischemia-reperfusion in rats
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150 kDa glycoprotein isolated from Solanum nigrum Linne enhances activities of detoxicant enzymes and lowers plasmic cholesterol in mouse
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Immunotherapy for the treatment of drug abuse
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The negative immunoregulatory effects of fluoxetine in relation to the cAMP-dependent PKA pathway
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Oral administration of bovine colostrum stimulates intestinal intraepithelial lymphocytes to polarize Th1-type in mice
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Critical roles of platelets in lipopolysaccharide-induced lethality: effects of glycyrrhizin and possible strategy for acute respiratory distress syndrome
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LASSBio-468: a new achiral thalidomide analogue which modulates TNF-α and NO production and inhibits endotoxic shock and arthritis in an animal model
Fulltext Access 10 Pages 2005
Combined treatment of glatiramer acetate and low doses of immunosuppressive drugs is effective in the prevention of graft rejection
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A soy diet accelerates renal damage in autoimmune MRL/Mp-lpr/lpr mice
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Arsenic trioxide overcomes apoptosis inhibition in K562/ADM cells by regulating vital components in apoptotic pathway
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An aqueous Chlorella extract inhibits IL-5 production by mast cells in vitro and reduces ovalbumin-induced eosinophil infiltration in the airway in mice in vivo
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Effects produced by Royal Jelly on haematopoiesis: relation with host resistance against Ehrlich ascites tumour challenge
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Characterization and immunostimulatory activity of an (1→6)-a-d-glucan from the root of Ipomoea batatas
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Protective effect of β-glucan against oxidative organ injury in a rat model of sepsis
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Tocilizumab inhibits signal transduction mediated by both mIL-6R and sIL-6R, but not by the receptors of other members of IL-6 cytokine family
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Characterisation of the in vitro modulation of splenocyte proliferation by non-4,5-epoxymorphinan opioids
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Anti-inflammatory activity of Seabuckthorn (Hippophae rhamnoides) leaves
Fulltext Access 10 Pages 2005
Efficacy of a traditional Korean medicine, Chung-Sang-Bo-Ha-Tang, in a murine model of chronic asthma
Fulltext Access 10 Pages 2005
Effects of Brazilian and Bulgarian propolis on bactericidal activity of macrophages against Salmonella Typhimurium
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A potent and selective inhibitor of group IIa secretory phospholipase A2 protects rats from TNBS-induced colitis
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Chemical complementation: A definitive phenotypic strategy for identifying small molecule inhibitors of elusive cellular targets
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An overview on biological mechanisms of PPARs
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Mediation of cell death by poly(ADP-ribose) polymerase-1
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Clinical perspectives of PARP inhibitors
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Methylamine but not mafenide mimics insulin-like activity of the semicarbazide-sensitive amine oxidase-substrate benzylamine on glucose tolerance and on human adipocyte metabolism
Fulltext Access 10 Pages 2005
Effect of elevated intraocular pressure on endothelin-1 in a rat model of glaucoma
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Poly(ADP-ribosyl)ation in asthma and other lung diseases
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Cardioprotective effects of poly(ADP-ribose) polymerase inhibition
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Selegiline modifies the extinction of responding following morphine self-administration, but does not alter cue-induced reinstatement, reacquisition of morphine reinforcement, or precipitated withdrawal
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Poly(ADP-ribosyl)ation and stroke
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Manganese oxidation state mediates toxicity in PC12 cells
Fulltext Access 11 Pages 2005
Mercury and autoimmunity: implications for occupational and environmental health
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Interactions between Streptomyces californicus and Stachybotrys chartarum can induce apoptosis and cell cycle arrest in mouse RAW264.7 macrophages
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Molecular events associated with arsenic-induced malignant transformation of human prostatic epithelial cells: aberrant genomic DNA methylation and K-ras oncogene activation
Fulltext Access 11 Pages 2005
Effect of intratracheal instillation of ultrafine carbon black on proinflammatory cytokine and chemokine release and mRNA expression in lung and lymph nodes of mice
Fulltext Access 11 Pages 2005
Formation of PAH-DNA adducts after in vivo and vitro exposure of rats and lung cells to different commercial carbon blacks
Fulltext Access 11 Pages 2005
Accumulation of methylmercury or polychlorinated biphenyls in in vitro models of rat neuronal tissue
Fulltext Access 11 Pages 2005
Assessment of cytotoxicity by emerging impedance spectroscopy
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Induction of Cyp1a1 and Cyp1b1 and formation of DNA adducts in C57BL/6, Balb/c, and F1 mice following in utero exposure to 3-methylcholanthrene
Fulltext Access 11 Pages 2005
Antidepressant-elicited changes in gene expression
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Use of concomitant medication with antipsychotic treatment in outpatients with schizophrenia: Results from the European Schizophrenia Outpatients Health Outcomes (SOHO) study
Fulltext Access 11 Pages 2005
Acrylonitrile potentiates hearing loss and cochlear damage induced by moderate noise exposure in rats
Fulltext Access 11 Pages 2005
Membrane phospholipid composition, alterations in neurotransmitter systems and schizophrenia
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Hepatic mitochondrial glutathione: transport and role in disease and toxicity
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Role of organic cation transporters in the renal handling of therapeutic agents and xenobiotics
Fulltext Access 11 Pages 2005
Thalidomide enhances both primary and secondary host resistances to Listeria monocytogenes infection by a neutrophil-related mechanism in female B6C3F1 mice
Fulltext Access 11 Pages 2005
Biotransformation and nephrotoxicity of ochratoxin B in rats
Fulltext Access 11 Pages 2005
4-Hydroxyestradiol induces oxidative stress and apoptosis in human mammary epithelial cells: possible protection by NF-κB and ERK/MAPK
Fulltext Access 11 Pages 2005
Inhibition of N-methyl-d-aspartate receptors increases paraoxon-induced apoptosis in cultured neurons
Fulltext Access 11 Pages 2005
Lipid peroxidation induced by carbon tetrachloride and its inhibition by antioxidant as evaluated by an oxidative stress marker, HODE
Fulltext Access 11 Pages 2005
Functional observational battery and motor activity in rats after single administration of two NHE 1 inhibitors
Fulltext Access 11 Pages 2005
A rat model of smoke inhalation injury: Influence of combustion smoke on gene expression in the brain
Fulltext Access 11 Pages 2005
Comparative sensitivity of rat cerebellar neurons to dysregulation of divalent cation homeostasis and cytotoxicity caused by methylmercury
Fulltext Access 11 Pages 2005
Sex- and dose-dependency in the pharmacokinetics and pharmacodynamics of (+)-methamphetamine and its metabolite (+)-amphetamine in rats
Fulltext Access 11 Pages 2005
Toxicokinetics of acrylamide and glycidamide in Fischer 344 rats
Fulltext Access 11 Pages 2005
Trouble shooting in toxicopathology
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How do male germ cells handle DNA damage?
Fulltext Access 11 Pages 2005
In vivo and in vitro anti-androgenic effects of DE-71, a commercial polybrominated diphenyl ether (PBDE) mixture
Fulltext Access 11 Pages 2005
Lignans, bacteriocides and organochlorine compounds activate the human pregnane X receptor (PXR)
Fulltext Access 11 Pages 2005
Capsaicin stimulates the non-store-operated Ca2+ entry but inhibits the store-operated Ca2+ entry in neutrophils
Fulltext Access 11 Pages 2005
Comprehensive non-clinical respiratory evaluation of promising new drugs
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Heavy metals modulate the activity of the purinergic P2X4 receptor
Fulltext Access 11 Pages 2005
Cytochrome P450 expression and activities in human tongue cells and their modulation by green tea extract
Fulltext Access 11 Pages 2005
Respiratory toxicity of multi-wall carbon nanotubes
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