The value of central-African traditional medicine for lead finding: Some case studies Fulltext Access 11 Pages 2015
Bi-specific antibodies with high antigen-binding affinity identified by flow cytometry Fulltext Access 11 Pages 2015
Androctonus australis hector venom contributes to the interaction between neuropeptides and mast cells in pulmonary hyperresponsiveness Fulltext Access 11 Pages 2015
The anti-malaria drug artesunate inhibits cigarette smoke and ovalbumin concurrent exposure-induced airway inflammation and might reverse glucocorticoid insensitivity Fulltext Access 11 Pages 2015
Cardiovascular pharmacologyThyroid hormone affects both endothelial and vascular smooth muscle cells in rat arteries Fulltext Access 11 Pages 2015
Neuropharmacology and analgesiaDissociation between the panicolytic effect of cannabidiol microinjected into the substantia nigra, pars reticulata, and fear-induced antinociception elicited by bicuculline administration in deep layers of the superior coll Fulltext Access 11 Pages 2015
Molecular and cellular pharmacologyArecoline inhibits intermediate-conductance calcium-activated potassium channels in human glioblastoma cell lines Fulltext Access 11 Pages 2015
The safety, efficacy and regulatory triangle in drug development: Impact for animal models and the use of animals Fulltext Access 11 Pages 2015
Mitochondrial fusion and fission proteins as novel therapeutic targets for treating cardiovascular disease Fulltext Access 11 Pages 2015
Epigenetic pathways in macrophages emerge as novel targets in atherosclerosis Fulltext Access 11 Pages 2015
Effects of 6 weeks oral administration of Phyllanthus acidus leaf water extract on the vascular functions of middle-aged male rats Fulltext Access 11 Pages 2015
Disulfiram-induced cytotoxicity and endo-lysosomal sequestration of zinc in breast cancer cells Fulltext Access 11 Pages 2015
Immunobiotic Lactobacillus administered post-exposure averts the lethal sequelae of respiratory virus infection Fulltext Access 11 Pages 2015
ReviewAnimal models of Middle East respiratory syndrome coronavirus infection Fulltext Access 11 Pages 2015
Pathogenesis of canine distemper virus in experimentally infected raccoon dogs, foxes, and minks Fulltext Access 11 Pages 2015
Combination of spices and herbal extract restores macrophage foam cell migration and abrogates the athero-inflammatory signalling cascade of atherogenesis Fulltext Access 11 Pages 2015
Asymmetric dimethyl arginine induces pulmonary vascular dysfunction via activation of signal transducer and activator of transcription 3 and stabilization of hypoxia-inducible factor 1-alpha Fulltext Access 11 Pages 2015
Endothelial transcriptomic changes induced by oxidized low density lipoprotein disclose an up-regulation of Jak–Stat pathway Fulltext Access 11 Pages 2015
Heart failure duration progressively modulates the arrhythmia substrate through structural and electrical remodeling Fulltext Access 11 Pages 2015
Midazolam treatment before re-exposure to contextual fear reduces freezing behavior and amygdala activity differentially in high- and low-anxiety rats Fulltext Access 11 Pages 2015
A pharmacokinetic model of oral methylphenidate in the rat and effects on behavior Fulltext Access 11 Pages 2015
Neurocognitive effects of acute choline supplementation in low, medium and high performer healthy volunteers Fulltext Access 11 Pages 2015
Orally administrated pterostilbene attenuates acute cerebral ischemia-reperfusion injury in a dose- and time-dependent manner in mice Fulltext Access 11 Pages 2015
Effects of early-life lead exposure on oxidative status and phagocytosis activity in great tits (Parus major) Fulltext Access 11 Pages 2015
Angiotensin type 1 receptor mediates chronic ethanol consumption-induced hypertension and vascular oxidative stress Fulltext Access 11 Pages 2015
Effect of soluble guanylyl cyclase activator and stimulator therapy on nitroglycerin-induced nitrate tolerance in rats Fulltext Access 11 Pages 2015
A precisely substituted benzopyran targets androgen refractory prostate cancer cells through selective modulation of estrogen receptors Fulltext Access 11 Pages 2015
Anti-cancerous efficacy and pharmacokinetics of 6-mercaptopurine loaded chitosan nanoparticles Fulltext Access 11 Pages 2015
Lycium barbarum polysaccharide improves traumatic cognition via reversing imbalance of apoptosis/regeneration in hippocampal neurons after stress Fulltext Access 11 Pages 2015
Molecular mechanisms behind the biological effects of hesperidin and hesperetin for the prevention of cancer and cardiovascular diseases Fulltext Access 11 Pages 2015
Isolation and characterization of cardiogenic, stem-like cardiac precursors from heart samples of patients with congenital heart disease Fulltext Access 11 Pages 2015
The potential physiological crosstalk and interrelationship between two sovereign endogenous amines, melatonin and homocysteine Fulltext Access 11 Pages 2015
Cecal inoculum peritonitis: An alternative model for sepsis vascular dysfunction study Fulltext Access 11 Pages 2015
Indigenous knowledge of folk medicines among tribal minorities in Khyber Pakhtunkhwa, northwestern Pakistan Fulltext Access 11 Pages 2015
Some popular medicinal plants and diseases of the Upper Palaeolithic in Western Georgia Fulltext Access 11 Pages 2015
Research PaperMetabolomic and lipidomic study of the protective effect of Chaihuang-Yishen formula on rats with diabetic nephropathy Fulltext Access 11 Pages 2015
Pharmacokinetics and tissue distribution of five bufadienolides from the Shexiang Baoxin pill following oral administration to mice Fulltext Access 11 Pages 2015
What's past is prologue: Chinese medicine and the treatment of recurrent urinary tract infections Fulltext Access 11 Pages 2015
A Chinese medicinal formulation ameliorates dextran sulfate sodium-induced experimental colitis by suppressing the activity of nuclear factor-kappaB signaling Fulltext Access 11 Pages 2015
An ethnobotanical survey of medicinal plants used by communities of Northern Kordofan region, Sudan Fulltext Access 11 Pages 2015
Identification of biosynthetic intermediates of teaghrelins and teaghrelin-like compounds in oolong teas, and their molecular docking to the ghrelin receptor Fulltext Access 11 Pages 2015
The pharmacokinetic study on the mechanism of toxicity attenuation of rhubarb total free anthraquinone oral colon-specific drug delivery system Fulltext Access 11 Pages 2015
Preclinical experimental stress studies: Protocols, assessment and comparison Fulltext Access 11 Pages 2015
Bumetanide is not capable of terminating status epilepticus but enhances phenobarbital efficacy in different rat models Fulltext Access 11 Pages 2015
Adiponectin induces apoptosis in hepatocellular carcinoma through differential modulation of thioredoxin proteins Fulltext Access 11 Pages 2015
Targeting the gyrase of Plasmodium falciparum with topoisomerase poisons Fulltext Access 11 Pages 2015
Duration of opioid receptor blockade determines biotherapeutic response Fulltext Access 11 Pages 2015
Guidelines for manuscript submission in the peer-reviewed pharmacological literature Fulltext Access 11 Pages 2015
Nicotinic ligands as multifunctional agents for the treatment of neuropsychiatric disorders Fulltext Access 11 Pages 2015
Low molecular weight heparin tinzaparin antagonizes cisplatin resistance of ovarian cancer cells Fulltext Access 11 Pages 2015
Metabolomics reveals the formation of aldehydes and iminium in gefitinib metabolism Fulltext Access 11 Pages 2015
Biological effects of interleukin-6: Clinical applications in autoimmune diseases and cancers Fulltext Access 11 Pages 2015
Insights into drug discovery from natural products through structural modification Fulltext Access 11 Pages 2015
Impact of chitosan composites and chitosan nanoparticle composites on various drug delivery systems: A review Fulltext Access 11 Pages 2015
Pharmacological synergism of bee venom and melittin with antibiotics and plant secondary metabolites against multi-drug resistant microbial pathogens Fulltext Access 11 Pages 2015
Development and Application of a Multiroute Physiologically Based Pharmacokinetic Model for Oxytetracycline in Dogs and Humans Fulltext Access 11 Pages 2015
Preparation of Caffeic Acid Phenethyl Ester-Incorporated Nanoparticles and Their Biological Activity Fulltext Access 11 Pages 2015
The Effects of Screw Configuration and Polymeric Carriers on Hot-Melt Extruded Taste-Masked Formulations Incorporated into Orally Disintegrating Tablets Fulltext Access 11 Pages 2015
Primary Packaging Considerations in Developing Medicines for Children: Oral Liquid and Powder for Constitution Fulltext Access 11 Pages 2015
The Granule Porosity Controls the Loss of Compactibility for Both Dry- and Wet-Processed Cellulose Granules but at Different Rate Fulltext Access 11 Pages 2015
Adult emotionality and neural plasticity as a function of adolescent nutrient supplementation in male rats Fulltext Access 11 Pages 2015
Gonadal hormones do not alter the development of antinociceptive tolerance to delta-9-tetrahydrocannabinol in adult rats Fulltext Access 11 Pages 2015
Individual differences in the behavioral effects of nicotine: A review of the preclinical animal literature Fulltext Access 11 Pages 2015
Platelet serotonin studies in hyperserotonemic relatives of children with autistic disorder Fulltext Access 11 Pages 2015
Further development of mathematical description for combined toxicity: A case study of lead–fluoride combination Fulltext Access 11 Pages 2015
Dietary administration of Nexrutine inhibits rat liver tumorigenesis and induces apoptotic cell death in human hepatocellular carcinoma cells Fulltext Access 11 Pages 2015
Data integration reveals key homeostatic mechanisms following low dose radiation exposure Fulltext Access 11 Pages 2015
Prenatal ethanol exposure-induced adrenal developmental abnormality of male offspring rats and its possible intrauterine programming mechanisms Fulltext Access 11 Pages 2015
Effects of amorphous silica coating on cerium oxide nanoparticles induced pulmonary responses Fulltext Access 11 Pages 2015
Differential cellular responses in healthy mice and in mice with established airway inflammation when exposed to hematite nanoparticles Fulltext Access 11 Pages 2015
Susceptibility to quantum dot induced lung inflammation differs widely among the Collaborative Cross founder mouse strains Fulltext Access 11 Pages 2015
Neuronal activity of the prefrontal cortex is reduced in rats selectively bred for deficient sensorimotor gating Fulltext Access 11 Pages 2015
Pharmacological therapy of acute ischaemic stroke: Achievements and problems Fulltext Access 11 Pages 2015
Cardiac fibroblasts as sentinel cells in cardiac tissue: Receptors, signaling pathways and cellular functions Fulltext Access 11 Pages 2015
Gamma-aminobutyric acid and alcohol actions: Neurochemical studies of long sleep and short sleep mice Fulltext Access 11 Pages 2015
Regulation of inflammation and proliferation of human bladder carcinoma cells by type-1 and type-2 cannabinoid receptors Fulltext Access 11 Pages 2015
Target-mediated pharmacokinetic/pharmacodynamic model based meta-analysis and dosing regimen optimization of a long-acting release formulation of exenatide in patients with type 2 diabetes mellitus Fulltext Access 11 Pages 2015
Significance of nitric oxide synthases: Lessons from triple nitric oxide synthases null mice Fulltext Access 11 Pages 2015
Pharmacist-provided diabetes management and education via a telemonitoring program Fulltext Access 11 Pages 2015
Patterns of use and expenses associated with mail-service pharmacy in adults with diabetes Fulltext Access 11 Pages 2015