Nitrapyrin: A scientific advisory group review of the mode of action and carcinogenicity in B6C3F1 mice Fulltext Access 13 Pages 2008
Physiologically based pharmacokinetic model development and simulations for ethylene dichloride (1,2-dichloroethane) in rats Fulltext Access 13 Pages 2008
Sub-cellular localization of manganese in the basal ganglia of normal and manganese-treated rats: An electron spectroscopy imaging and electron energy-loss spectroscopy study Fulltext Access 13 Pages 2008
Pyrethroid modulation of spontaneous neuronal excitability and neurotransmission in hippocampal neurons in culture Fulltext Access 13 Pages 2008
Microbiological quality of indoor and outdoor swimming pools in Greece: Investigation of the antibiotic resistance of the bacterial isolates Fulltext Access 13 Pages 2008
Comparison of phenotypic and genotypic methods for the detection of environmental isolates of Pseudomonas aeruginosa Fulltext Access 13 Pages 2008
Assessment of dioxin and dioxin-like compounds in mainstream smoke from selected US cigarette brands and reference cigarettes Fulltext Access 13 Pages 2008
The anticancer effect of protein-extract from Bidens alba in human colorectal carcinoma SW480 cells via the reactive oxidative species- and glutathione depletion-dependent apoptosis Fulltext Access 13 Pages 2008
Transcriptome analysis provides new insights into liver changes induced in the rat upon dietary administration of the food additives butylated hydroxytoluene, curcumin, propyl gallate and thiabendazole Fulltext Access 13 Pages 2008
Exposure to airborne amphibole structures and health risks: Libby, Montana Fulltext Access 13 Pages 2008
Subchronic feeding study of herbicide–tolerant soybean DP-356Ø43-5 in Sprague–Dawley rats Fulltext Access 13 Pages 2008
Toxicological evaluation of potassium sorbate added to cigarette tobacco Fulltext Access 13 Pages 2008
Pleurotus ostreatus, an oyster mushroom, decreases the oxidative stress induced by carbon tetrachloride in rat kidneys, heart and brain Fulltext Access 13 Pages 2008
Potential health effects of exposure to carcinogenic compounds in incense smoke in temple workers Fulltext Access 13 Pages 2008
Regulation of endothelial permeability by Src kinase signaling: Vascular leakage versus transcellular transport of drugs and macromolecules Fulltext Access 13 Pages 2008
Copper–adenine complex, a compound, with multi-biochemical targets and potential anti-cancer effect Fulltext Access 13 Pages 2008
Beneficial effect of zinc supplementation on biomechanical properties of femoral distal end and femoral diaphysis of male rats chronically exposed to cadmium Fulltext Access 13 Pages 2008
Insulin secretagogue effect of Ichnocarpus frutescence leaf extract in experimental diabetes: A dose-dependent study Fulltext Access 13 Pages 2008
Effect of gamma irradiated hyaluronic acid on acetaminophen induced acute hepatotoxicity Fulltext Access 13 Pages 2008
Changes of cytoskeletal proteins in nerve tissues and serum of rats treated with 2,5-hexanedione Fulltext Access 13 Pages 2008
An in vitro blood-brain barrier model for high throughput (HTS) toxicological screening Fulltext Access 13 Pages 2008
Evaluation of beneficial and adverse effects of glucocorticoids on a newly developed full-thickness skin model Fulltext Access 13 Pages 2008
Cell types involved in allergic asthma and their use in in vitro models to assess respiratory sensitization Fulltext Access 13 Pages 2008
Novel mammalian cell lines expressing reporter genes for the detection of environmental chemicals activating endogenous aryl hydrocarbon receptors (ArhR) or estrogen receptors (ER) Fulltext Access 13 Pages 2008
Prediction of the health effects of polychlorinated biphenyls (PCBs) and their metabolites using quantitative structure–activity relationship (QSAR) Fulltext Access 13 Pages 2008
Acrolein oxidizes the cytosolic and mitochondrial thioredoxins in human endothelial cells Fulltext Access 13 Pages 2008
Influence of ferulic acid on nicotine-induced lipid peroxidation, DNA damage and inflammation in experimental rats as compared to N-acetylcysteine Fulltext Access 13 Pages 2008
Examination of mRNA expression in rat hearts and lungs for analysis of effects of exposure to concentrated ambient particles on cardiovascular function Fulltext Access 13 Pages 2008
Cardiac troponin is the most effective translational safety biomarker for myocardial injury in cardiotoxicity Fulltext Access 13 Pages 2008
Comparative assessment of early acute lung injury in mice and rats exposed to 1,6-hexamethylene diisocyanate–polyisocyanate aerosols Fulltext Access 13 Pages 2008
Low joining efficiency and non-conservative repair of two distant double-strand breaks in mouse embryonic stem cells Fulltext Access 13 Pages 2008
Perfluorooctane sulfonate-induced changes in fetal rat liver gene expression Fulltext Access 13 Pages 2008
Effect of treatment with cadmium on kinetic properties of Na+, K+-ATPase and glucose-6-phosphatase activity in rat liver microsomes: A correlative study on influence of lipid/phospholipid make-up Fulltext Access 13 Pages 2008
Potential adverse effects of phthalic acid esters on human health: A review of recent studies on reproduction Fulltext Access 13 Pages 2008
Safety assessment of SDA soybean oil: Results of a 28-day gavage study and a 90-day/one generation reproduction feeding study in rats Fulltext Access 13 Pages 2008
Testing REACH draft technical guidance notes for conducting chemical safety assessments—The experience of a downstream user of a preparation Fulltext Access 13 Pages 2008
A review of carcinogenicity studies of asbestos and non-asbestos tremolite and other amphiboles Fulltext Access 13 Pages 2008
Comparative analysis of in vivo interactions between Rev1 protein and other Y-family DNA polymerases in animals and yeasts Fulltext Access 13 Pages 2008
Developmental neurotoxicity of Propylthiouracil (PTU) in rats: Relationship between transient hypothyroxinemia during development and long-lasting behavioural and functional changes Fulltext Access 13 Pages 2008
Adenosine 3â²,5â²-cyclic monophosphate (cAMP)-dependent phosphoregulation of mitochondrial complex I is inhibited by nucleoside reverse transcriptase inhibitors Fulltext Access 13 Pages 2008
Respiratory sensitization and allergy: Current research approaches and needs Fulltext Access 13 Pages 2008
Dithiothreitol abrogates the effect of arsenic trioxide on normal rat liver mitochondria and human hepatocellular carcinoma cells Fulltext Access 13 Pages 2008
Toxicogenomic analysis of the hepatic effects of perfluorooctanoic acid on rare minnows (Gobiocypris rarus) Fulltext Access 13 Pages 2008
The heavy metal cadmium induces valosin-containing protein (VCP)-mediated aggresome formation Fulltext Access 13 Pages 2008
Lipopolysaccharide induces VCAM-1 expression and neutrophil adhesion to human tracheal smooth muscle cells: Involvement of Src/EGFR/PI3-K/Akt pathway Fulltext Access 13 Pages 2008
A new lactoferrin- and iron-dependent lysosomal death pathway is induced by benzo[a]pyrene in hepatic epithelial cells Fulltext Access 13 Pages 2008
Mechanisms by which herpes simplex virus DNA polymerase limits translesion synthesis through abasic sites Fulltext Access 13 Pages 2008
Aclarubicin-induced ROS generation and collapse of mitochondrial membrane potential in human cancer cell lines Fulltext Access 13 Pages 2008
Oxidation of mitochondrial deoxynucleotide pools by exposure to sodium nitroprusside induces cell death Fulltext Access 13 Pages 2008
Growth of persistent foci of DNA damage checkpoint factors is essential for amplification of G1 checkpoint signaling Fulltext Access 13 Pages 2008
Cooperative damage recognition by UvrA and UvrB: Identification of UvrA residues that mediate DNA binding Fulltext Access 13 Pages 2008
Substrate specificity and sequence-dependent activity of the Saccharomyces cerevisiae 3-methyladenine DNA glycosylase (Mag) Fulltext Access 13 Pages 2008
Transcription of DNA containing the 5-guanidino-4-nitroimidazole lesion by human RNA polymerase II and bacteriophage T7 RNA polymerase Fulltext Access 13 Pages 2008
The rate of base excision repair of uracil is controlled by the initiating glycosylase Fulltext Access 13 Pages 2008
Surveillance mechanisms monitoring chromosome breaks during mitosis and meiosis Fulltext Access 13 Pages 2008
The Forensic Science Society Summer Conference “Benefits of Hindsight” Crowne Plaza Hotel, Glasgow, Drug Profiling, 6th-8th July 2007 Fulltext Access 13 Pages 2008
Genotoxicity of intermittent co-exposure to benzene and toluene in male CD-1 mice Fulltext Access 13 Pages 2008
Tumor necrosis factor-α induces MMP-9 expression via p42/p44 MAPK, JNK, and nuclear factor-κB in A549 cells Fulltext Access 13 Pages 2008
Reactive oxygen species-dependent HSP90 protein cleavage participates in arsenical As+ 3- and MMA+ 3-induced apoptosis through inhibition of telomerase activity via JNK activation Fulltext Access 13 Pages 2008
Central role of mitochondria and p53 in PUVA-induced apoptosis in human keratinocytes cell line NCTC-2544 Fulltext Access 13 Pages 2008
Response of human renal tubular cells to cyclosporine and sirolimus: A toxicogenomic study Fulltext Access 13 Pages 2008
Apoptotic death induced by the cyclophosphamide analogue mafosfamide in human lymphoblastoid cells: Contribution of DNA replication, transcription inhibition and Chk/p53 signaling Fulltext Access 13 Pages 2008
Characterization of biliary conjugates of 4,4′-methylenedianiline in male versus female rats Fulltext Access 13 Pages 2008
Transcriptional responses in thyroid tissues from rats treated with a tumorigenic and a non-tumorigenic triazole conazole fungicide Fulltext Access 13 Pages 2008
Gene expression profiles modulated by the human carcinogen aristolochic acid I in human cancer cells and their dependence on TP53 Fulltext Access 13 Pages 2008
Toxicological effects of cinnabar in rats by NMR-based metabolic profiling of urine and serum Fulltext Access 13 Pages 2008
A decisive role of mitochondria in defining rate and intensity of apoptosis induction by different alkaloids Fulltext Access 14 Pages 2008
A 28-day oral dose toxicity study enhanced to detect endocrine effects of a purified technical pentabromodiphenyl ether (pentaBDE) mixture in Wistar rats Fulltext Access 14 Pages 2008
Endocrine effects of tetrabromobisphenol-A (TBBPA) in Wistar rats as tested in a one-generation reproduction study and a subacute toxicity study Fulltext Access 14 Pages 2008
Quantitative evaluation of dichloroacetic acid kinetics in human—a physiologically based pharmacokinetic modeling investigation Fulltext Access 14 Pages 2008
Oxidative stress and DNA damage induced by cadmium in the human keratinocyte HaCaT cell line: Role of glutathione in the resistance to cadmium Fulltext Access 14 Pages 2008
Multiendpoint mechanistic profiling of hepatotoxicants in HepG2/C3A human hepatoma cells and novel statistical approaches for development of a prediction model for acute hepatotoxicity Fulltext Access 14 Pages 2008
A cell-permeable peptide inhibitor TAT-JBD reduces the MPP+-induced caspase-9 activation but does not prevent the dopaminergic degeneration in substantia nigra of rats Fulltext Access 14 Pages 2008
Gene expression profiles in the cerebellum and hippocampus following exposure to a neurotoxicant, Aroclor 1254: Developmental effects Fulltext Access 14 Pages 2008
Potential in vitro antioxidant and protective effects of Soymida febrifuga on ethanol induced oxidative damage in HepG2 cells Fulltext Access 14 Pages 2008
Anticarcinogenesis by dietary phytochemicals: Cytoprotection by Nrf2 in normal cells and cytotoxicity by modulation of transcription factors NF-κB and AP-1 in abnormal cancer cells Fulltext Access 14 Pages 2008
Clofibrate and gemfibrozil induce an embryonic malabsorption syndrome in zebrafish Fulltext Access 14 Pages 2008
Relevance of integrating agricultural practices in pesticide dietary intake indicator Fulltext Access 14 Pages 2008
Androgenic endocrine disruptors in wastewater treatment plant effluents in India: Their influence on reproductive processes and systemic toxicity in male rats Fulltext Access 14 Pages 2008
Overlapping gene expression profiles of model compounds provide opportunities for immunotoxicity screening Fulltext Access 14 Pages 2008
Inhalation carcinogenicity study with nickel metal powder in Wistar rats Fulltext Access 14 Pages 2008
Apigenin inhibits HGF-promoted invasive growth and metastasis involving blocking PI3K/Akt pathway and β4 integrin function in MDA-MB-231 breast cancer cells Fulltext Access 14 Pages 2008
Effects of naturally occurring coumarins on hepatic drug-metabolizing enzymes inmice Fulltext Access 14 Pages 2008
Subchronic effects of valproic acid on gene expression profiles for lipid metabolism in mouse liver Fulltext Access 14 Pages 2008
Intense pseudotransport of a cationic drug mediated by vacuolar ATPase: Procainamide-induced autophagic cell vacuolization Fulltext Access 14 Pages 2008
Environment, diet and CpG island methylation: Epigenetic signals in gastrointestinal neoplasia Fulltext Access 14 Pages 2008
In vitro expression of hard metal dust (WC–Co) — responsive genes in human peripheral blood mononucleated cells Fulltext Access 14 Pages 2008
Arylamine N-acetyltransferases: Structural and functional implications of polymorphisms Fulltext Access 14 Pages 2008
Secretory phospholipase A2 mediates progression of acute liver injury in the absence of sufficient cyclooxygenase-2 Fulltext Access 14 Pages 2008
Dosimetry considerations in the enhanced sensitivity of male Wistar rats to chronic ethylene glycol-induced nephrotoxicity Fulltext Access 14 Pages 2008
Efficacy of a plant extract (Chelidonium majus L.) in combating induced hepatocarcinogenesis in mice Fulltext Access 14 Pages 2008
Aldo-keto reductase 1C2 is essential for 1-nitropyrene's but not for benzo[a]pyrene's induction of p53 phosphorylation and apoptosis Fulltext Access 14 Pages 2008