A risk-based classification scheme for genetically modified foods II: Graded testing Fulltext Access 12 Pages 2008
A toxicogenomics approach for early assessment of potential non-genotoxic hepatocarcinogenicity of chemicals in rats Fulltext Access 12 Pages 2008
Possible role for early-life immune insult including developmental immunotoxicity in chronic fatigue syndrome (CFS) or myalgic encephalomyelitis (ME) Fulltext Access 12 Pages 2008
The environmental pollutant and carcinogen 3-nitrobenzanthrone induces cytochrome P450 1A1 and NAD(P)H:quinone oxidoreductase in rat lung and kidney, thereby enhancing its own genotoxicity Fulltext Access 12 Pages 2008
Ebselen increases cytosolic free Ca2+ concentration, stimulates glutamate release and increases GFAP content in rat hippocampal astrocytes Fulltext Access 12 Pages 2008
Yessotoxin induces the accumulation of altered E-cadherin dimers that are not part of adhesive structures in intact cells Fulltext Access 12 Pages 2008
Protective effect of minocycline, a semi-synthetic second-generation tetracycline against 3-nitropropionic acid (3-NP)-induced neurotoxicity Fulltext Access 12 Pages 2008
Ciglitazone induces caspase-independent apoptosis via p38-dependent AIF nuclear translocation in renal epithelial cells Fulltext Access 12 Pages 2008
Subchronic toxicity and toxicokinetics of LZB, a new proton pump inhibitor, after 13-week repeated oral administration in dogs Fulltext Access 12 Pages 2008
Low-level arsenic exposure in drinking water and bladder cancer: A review and meta-analysis Fulltext Access 12 Pages 2008
Application of PBPK modeling in support of the derivation of toxicity reference values for 1,1,1-trichloroethane Fulltext Access 12 Pages 2008
A retrospective analysis of developmental toxicity studies in rat and rabbit: What is the added value of the rabbit as an additional test species? Fulltext Access 12 Pages 2008
Biomonitoring Equivalents (BE) dossier for 2,4-dichlorophenoxyacetic acid (2,4-D) (CAS No. 94-75-7) Fulltext Access 12 Pages 2008
Guidelines for the derivation of Biomonitoring Equivalents: Report from the Biomonitoring Equivalents Expert Workshop Fulltext Access 12 Pages 2008
Development of good modelling practice for physiologically based pharmacokinetic models for use in risk assessment: The first steps Fulltext Access 12 Pages 2008
Effects of MTBE on the reported incidence of Leydig cell tumors in Sprague-Dawley rats: Range of possible Poly-3 results Fulltext Access 12 Pages 2008
Gestational ethanol and nicotine exposure: Effects on maternal behavior, oxytocin, and offspring ethanol intake in the rat Fulltext Access 12 Pages 2008
How environmental and genetic factors combine to cause autism: A redox/methylation hypothesis Fulltext Access 12 Pages 2008
A neurobehavioral study of current and former welders exposed to manganese Fulltext Access 12 Pages 2008
A novel in vitro metabolomics approach for neurotoxicity testing, proof of principle for methyl mercury chloride and caffeine Fulltext Access 12 Pages 2008
Successful prevalidation of the slug mucosal irritation test to assess the eye irritation potency of chemicals Fulltext Access 12 Pages 2008
Evaluation of in vitro cytotoxicity and paracellular permeability of intact monolayers with mouse embryonic stem cells Fulltext Access 12 Pages 2008
First steps in establishing a developmental toxicity test method based on human embryonic stem cells Fulltext Access 12 Pages 2008
Differential expression of genes associated with cell proliferation and apoptosis induced by okadaic acid during the transformation process of BALB/c 3T3 cells Fulltext Access 12 Pages 2008
Assessment of the content of phenolics and antioxidant actions of the Rubiaceae, Ebenaceae, Celastraceae, Erythroxylaceae and Sterculaceae families of Mauritian endemic plants Fulltext Access 12 Pages 2008
Effects of cell type and culture media on Interleukin-6 secretion in response to environmental particles Fulltext Access 12 Pages 2008
2,4-Dinitrophenol induces G1 phase arrest and apoptosis in human pulmonary adenocarcinoma Calu-6 cells Fulltext Access 12 Pages 2008
Theaflavin-3,3′-digallate, a component of black tea: An inducer of oxidative stress and apoptosis Fulltext Access 12 Pages 2008
Screening and detection of the in vitro agonistic activity of xenobiotics on the retinoic acid receptor Fulltext Access 12 Pages 2008
2-Deoxy-d-ribose-induced oxidative stress causes apoptosis in human monocytic cells: Prevention by pyridoxal-5′-phosphate Fulltext Access 12 Pages 2008
High concentrations of stavudine impair fatty acid oxidation without depleting mitochondrial DNA in cultured rat hepatocytes Fulltext Access 12 Pages 2008
Differences in simulated liver concentrations of toxic coumarin metabolites in rats and different human populations evaluated through physiologically based biokinetic (PBBK) modeling Fulltext Access 12 Pages 2008
Effect of an experimental proteasome inhibitor on the cytoskeleton, cytosolic protein turnover, and induction in the neuronal cells in vitro Fulltext Access 12 Pages 2008
Iron deficiency causes duodenum mucosal hyperplasia in male Wistar rats Fulltext Access 12 Pages 2008
A feasibility study developing an integrated testing strategy assessing skin irritation potential of chemicals Fulltext Access 12 Pages 2008
Identification of formaldehyde-responsive genes by suppression subtractive hybridization Fulltext Access 12 Pages 2008
Effect of Pyrethrins on cytochrome P450 forms in cultured rat and human hepatocytes Fulltext Access 12 Pages 2008
Potential role of cysteine and methionine in the protection against hormonal imbalance and mutagenicity induced by furazolidone in female rats Fulltext Access 12 Pages 2008
Thioacetamide accelerates steatohepatitis, cirrhosis and HCC by expressing HCV core protein in transgenic zebrafish Danio rerio Fulltext Access 12 Pages 2008
Hexavalent chromium causes the oxidation of thioredoxin in human bronchial epithelial cells Fulltext Access 12 Pages 2008
Plastic components affect the activation of the aryl hydrocarbon and the androgen receptor Fulltext Access 12 Pages 2008
Investigation of the effect of a panel of model hepatotoxins on the Nrf2-Keap1 defence response pathway in CD-1 mice Fulltext Access 12 Pages 2008
Possible involvement of gadolinium chelates in the pathophysiology of nephrogenic systemic fibrosis: A critical review Fulltext Access 12 Pages 2008
Community program therapist adherence and competence in motivational enhancement therapy Fulltext Access 12 Pages 2008
Simultaneous application of t-test and fold change criteria to identify acetaminophen and carbon tetrachloride affected genes in mice liver Fulltext Access 12 Pages 2008
Nitrophenols isolated from diesel exhaust particles regulate steroidogenic gene expression and steroid synthesis in the human H295R adrenocortical cell line Fulltext Access 12 Pages 2008
Implication of caspases and subcellular compartments in tert-butylhydroperoxide induced apoptosis Fulltext Access 12 Pages 2008
Fullerene C60 exposure elicits an oxidative stress response in embryonic zebrafish Fulltext Access 12 Pages 2008
Fluoride-induced IL-8 release in human epithelial lung cells: Relationship to EGF-receptor-, SRC- and MAP-kinase activation Fulltext Access 12 Pages 2008
Aneuploidy in upper gastro-intestinal tract cancers—A potential prognostic marker? Fulltext Access 12 Pages 2008
Mutagenic potential of DNA–peptide crosslinks mediated by acrolein-derived DNA adducts Fulltext Access 12 Pages 2008
Polymorphisms in genes involved in the inflammatory response and interaction with NSAID use or smoking in relation to lung cancer risk in a prospective study Fulltext Access 12 Pages 2008
The MAO-A gene, platelet MAO-B activity and psychosocial environment in adolescent female alcohol-related problem behaviour Fulltext Access 12 Pages 2008
Morphine and methadone pre-exposures differently modify brain regional Fos protein expression and locomotor activity responses to morphine challenge in the rat Fulltext Access 12 Pages 2008
Reward-related decision-making deficits and elevated impulsivity among MDMA and other drug users Fulltext Access 12 Pages 2008
Substance use outcomes 5½ years past baseline for partnership-based, family-school preventive interventions Fulltext Access 12 Pages 2008
P38-associated pathway involvement in apoptosis induced by photodynamic therapy with Lonicera japonica in human lung squamous carcinoma CH27 cells Fulltext Access 12 Pages 2008
Age of onset and temporal sequencing of lifetime DSM-IV alcohol use disorders relative to comorbid mood and anxiety disorders Fulltext Access 12 Pages 2008
Long-term psychiatric and medical consequences of anabolic–androgenic steroid abuse: A looming public health concern? Fulltext Access 12 Pages 2008
The relative abuse liability of oral oxycodone, hydrocodone and hydromorphone assessed in prescription opioid abusers Fulltext Access 12 Pages 2008
Family interventions and their effect on adolescent alcohol use in general populations; a meta-analysis of randomized controlled trials Fulltext Access 12 Pages 2008
Chronic ethanol exposure leads to divergent control of dopaminergic synapses in distinct target regions Fulltext Access 12 Pages 2008
Children's hedonic responses to the odors of alcoholic beverages: A window to emotions Fulltext Access 12 Pages 2008
Chemical, physical and mineralogical characterization of soils from the Curitiba Metropolitan Region for forensic purpose Fulltext Access 12 Pages 2008
Some phytochemical, pharmacological and toxicological properties of ginger (Zingiber officinale Roscoe): A review of recent research Fulltext Access 12 Pages 2008
Application of in vitro neurotoxicity testing for regulatory purposes: Symposium III summary and research needs Fulltext Access 12 Pages 2008
The impact of solvent mixtures on neurobehavioral performance—Conclusions from epidemiological data Fulltext Access 12 Pages 2008
The protective effect of neuronal nitric oxide synthase (nNOS) against alcohol toxicity depends upon the NO-cGMP-PKG pathway and NF-κB Fulltext Access 12 Pages 2008
Influence of low level maternal Pb exposure and prenatal stress on offspring stress challenge responsivity Fulltext Access 12 Pages 2008
A comparison of efficiencies of microbiological pollution removal in six sewage treatment plants with different treatment systems Fulltext Access 12 Pages 2008
28-Day oral (gavage) toxicity studies of green tea catechins prepared for beverages in rats Fulltext Access 12 Pages 2008
In vitro and in vivo reduction of sodium arsenite induced toxicity by aqueous garlic extract Fulltext Access 12 Pages 2008
The toxicological effects of petroleum spray oils on insects – Evidence for an alternative mode of action and possible new control options Fulltext Access 12 Pages 2008
Identification of superoxide dismutase as a potential urinary marker of carbon tetrachloride-induced hepatic toxicity Fulltext Access 12 Pages 2008
Role of the p50 subunit of NF-κB in vitamin E-induced changes in mice treated with the peroxisome proliferator, ciprofibrate Fulltext Access 12 Pages 2008
Flavones and flavonols exert cytotoxic effects on a human oesophageal adenocarcinoma cell line (OE33) by causing G2/M arrest and inducing apoptosis Fulltext Access 12 Pages 2008
Acute and repeated dose oral toxicity of N-acetyl-l-aspartic acid in Sprague–Dawley rats Fulltext Access 12 Pages 2008
Cinnamaldehyde inhibits pro-inflammatory cytokines secretion from monocytes/macrophages through suppression of intracellular signaling Fulltext Access 12 Pages 2008
The BIOSAFEPAPER project for in vitro toxicity assessments: Preparation, detailed chemical characterisation and testing of extracts from paper and board samples Fulltext Access 12 Pages 2008
Evaluation of Azadirachta indica leaf fractions for in vitro antioxidant potential and in vivo modulation of biomarkers of chemoprevention in the hamster buccal pouch carcinogenesis model Fulltext Access 12 Pages 2008
Dietary isoflavones in the prevention of cardiovascular disease – A molecular perspective Fulltext Access 12 Pages 2008